Cannabis Compound Database: Showing Compound Card for Ascorbic acid (CDB004789)

Jump To Section:

Identification Taxonomy Ontology Physical properties Spectra Protein target Pathways Concentrations Links References enzymes (26)transporters (3) Show 53 proteins XML

Record Information

Version

1.0

Created at

2020-04-17 18:36:56 UTC

Updated at

2020-12-07 19:10:56 UTC

CannabisDB ID

CDB004789

Secondary Accession Numbers

Not Available

Cannabis Compound Identification

Common Name

Ascorbic acid

Description

Ascorbic acid, also known as acide ascorbique or L-ascorbate, belongs to the class of organic compounds known as butenolides. These are dihydrofurans with a carbonyl group at the C2 carbon atom. Ascorbic acid is a drug which is used to treat vitamin c deficiency, scurvy, delayed wound and bone healing, urine acidification, and in general as an antioxidant. it has also been suggested to be an effective antiviral agent. Ascorbic acid is an extremely weak basic (essentially neutral) compound (based on its pKa). dopamine and ascorbic acid can be converted into norepinephrine and dehydroascorbic acid through the action of the enzyme dopamine beta-hydroxylase. In humans, ascorbic acid is involved in the metabolic disorder called tyrosinemia, transient, of the newborn. Ascorbic acid is a very mild and grassy tasting compound. Outside of the human body, Ascorbic acid is found, on average, in the highest concentration within a few different foods, such as acerola, pepper (c. frutescens), and orange bell peppers and in a lower concentration in yogurts, yardlong beans, and peanuts. Ascorbic acid has also been detected, but not quantified in, several different foods, such as deerberries, cetacea (dolphin, porpoise, whale), acorns, lemon balms, and gelatins. This could make ascorbic acid a potential biomarker for the consumption of these foods. The L-enantiomer of ascorbic acid and conjugate acid of L-ascorbate. Ascorbic acid is expected to be in Cannabis as all living plants are known to produce and metabolize it.

Structure

MOL SDF 3D-SDF PDB SMILES InChI View 3D Structure

Synonyms

Value	Source
Acide ascorbique	ChEBI
Acido ascorbico	ChEBI
Acidum ascorbicum	ChEBI
Acidum ascorbinicum	ChEBI
Ascoltin	ChEBI
Ascorbicap	ChEBI
Ascorbinsaeure	ChEBI
e 300	ChEBI
e-300	ChEBI
e300	ChEBI
L-(+)-Ascorbic acid	ChEBI
L-Ascorbate	ChEBI
Vitamin C	ChEBI
Monodehydroascorbate radical	Kegg
Ascorbate radical	Kegg
Semidehydroascorbic acid	Kegg
ASCOR	Kegg
L-(+)-Ascorbate	Generator
L-Ascorbic acid	Generator
Monodehydroascorbic acid radical	Generator
Ascorbic acid radical	Generator
Semidehydroascorbate	Generator
Ascorbate	Generator
(+)-Ascorbate	HMDB
(+)-Ascorbic acid	HMDB
(+)-Sodium L-ascorbate	HMDB
3-keto-L-Gulofuranolactone	HMDB
3-oxo-L-Gulofuranolactone	HMDB
Adenex	HMDB
Allercorb	HMDB
Antiscorbic vitamin	HMDB
Antiscorbutic vitamin	HMDB
arco-Cee	HMDB
Ascor-b.i.d.	HMDB
Ascorb	HMDB
Ascorbajen	HMDB
Ascorbicab	HMDB
Ascorbicin	HMDB
Ascorbin	HMDB
Ascorbutina	HMDB
Ascorin	HMDB
Ascorteal	HMDB
Ascorvit	HMDB
C-Level	HMDB
C-Long	HMDB
C-Quin	HMDB
C-Span	HMDB
C-Vimin	HMDB
Cantan	HMDB
Cantaxin	HMDB
Catavin C	HMDB
Ce lent	HMDB
Ce-mi-lin	HMDB
Ce-vi-sol	HMDB
Cebicure	HMDB
Cebid	HMDB
Cebion	HMDB
Cebione	HMDB
Cecon	HMDB
Cee-caps TD	HMDB
Cee-vite	HMDB
Cegiolan	HMDB
Ceglion	HMDB
Ceklin	HMDB
Celaskon	HMDB
Celin	HMDB
Cell C	HMDB
Cemagyl	HMDB
Cemill	HMDB
Cenetone	HMDB
Cenolate	HMDB
Cereon	HMDB
Cergona	HMDB
Cescorbat	HMDB
Cetamid	HMDB
Cetane	HMDB
Cetane-caps TC	HMDB
Cetane-caps TD	HMDB
Cetebe	HMDB
Cetemican	HMDB
Cevalin	HMDB
Cevatine	HMDB
Cevex	HMDB
Cevi-bid	HMDB
Cevimin	HMDB
Cevital	HMDB
Cevitamate	HMDB
Cevitamic acid	HMDB
Cevitamin	HMDB
Cevitan	HMDB
Cevitex	HMDB
Cewin	HMDB
Chewcee	HMDB
Ciamin	HMDB
Cipca	HMDB
Citriscorb	HMDB
Citrovit	HMDB
Colascor	HMDB
Concemin	HMDB
Davitamon C	HMDB
Dora-C-500	HMDB
Duoscorb	HMDB
Ferrous ascorbate	HMDB, MeSH
gamma-Lactone L-threo-hex-2-enonate	HMDB
gamma-Lactone L-threo-hex-2-enonic acid	HMDB
HiCee	HMDB
Hybrin	HMDB, MeSH
ido-C	HMDB
Juvamine	HMDB
Kangbingfeng	HMDB
Kyselina askorbova	HMDB
L(+)-Ascorbate	HMDB
L(+)-Ascorbic acid	HMDB
L-3-Ketothreohexuronic acid lactone	HMDB
L-Lyxoascorbate	HMDB
L-Lyxoascorbic acid	HMDB
L-threo-Ascorbic acid	HMDB
L-Xyloascorbate	HMDB
L-Xyloascorbic acid	HMDB
Laroscorbine	HMDB
Lemascorb	HMDB
Liqui-cee	HMDB
Meri-c	HMDB
Natrascorb	HMDB
Natrascorb injectable	HMDB
Planavit C	HMDB
Proscorbin	HMDB
Redoxon	HMDB
Ribena	HMDB
Ronotec 100	HMDB
Rontex 100	HMDB
Roscorbic	HMDB
Rovimix C	HMDB
Scorbacid	HMDB
Scorbu C	HMDB
Scorbu-C	HMDB
Secorbate	HMDB
Sodascorbate	HMDB
Suncoat VC 40	HMDB
Testascorbic	HMDB
VASC	HMDB
Vicelat	HMDB
Vicin	HMDB
Vicomin C	HMDB
Viforcit	HMDB
Viscorin	HMDB
Viscorin 100m	HMDB
Vitace	HMDB
Vitacee	HMDB
Vitacimin	HMDB
Vitacin	HMDB
Vitamisin	HMDB
Vitascorbol	HMDB
Xitix	HMDB
L Ascorbic acid	MeSH, HMDB
Acid, ascorbic	MeSH, HMDB
Ascorbate, ferrous	MeSH, HMDB
Ascorbate, sodium	MeSH, HMDB
Magnesium ascorbate	MeSH, HMDB
Magnesium ascorbicum	MeSH, HMDB
Magnesium di-L-ascorbate	MeSH, HMDB
Di-L-ascorbate, magnesium	MeSH, HMDB
Ascorbic acid, monosodium salt	MeSH, HMDB
Magnesium di L ascorbate	MeSH, HMDB
Magnorbin	MeSH, HMDB
Sodium ascorbate	MeSH, HMDB
Acid, L-ascorbic	MeSH, HMDB
Ascorbate, magnesium	MeSH, HMDB
ASCORBIC ACID	ChEBI

Chemical Formula

C₆H₈O₆

Average Molecular Weight

176.12

Monoisotopic Molecular Weight

176.0321

IUPAC Name

(5R)-5-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-2,5-dihydrofuran-2-one

Traditional Name

vitamin C

CAS Registry Number

50-81-7

SMILES

[H][C@@]1(OC(=O)C(O)=C1O)[C@@H](O)CO

InChI Identifier

InChI=1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1

InChI Key

CIWBSHSKHKDKBQ-JLAZNSOCSA-N

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as butenolides. These are dihydrofurans with a carbonyl group at the C2 carbon atom.

Kingdom

Organic compounds

Super Class

Organoheterocyclic compounds

Class

Dihydrofurans

Sub Class

Furanones

Direct Parent

Butenolides

Alternative Parents

Substituents

2-furanone
Vinylogous acid
Alpha,beta-unsaturated carboxylic ester
Enoate ester
1,2-diol
Carboxylic acid ester
Enediol
Secondary alcohol
Lactone
Carboxylic acid derivative
Oxacycle
Monocarboxylic acid or derivatives
Alcohol
Hydrocarbon derivative
Organic oxygen compound
Carbonyl group
Organic oxide
Primary alcohol
Organooxygen compound
Aliphatic heteromonocyclic compound

Molecular Framework

Aliphatic heteromonocyclic compounds

External Descriptors

ascorbic acid (CHEBI:29073 )
Water-soluble vitamins (C00072 )

Ontology

Physiological effect

Health effect:

Health condition:

Infections and infestations:

Meningitis

Disposition

Route of exposure:

Enteral:

Ingestion

Source:

Food

Biological:

Animal

Microbe:

Ketogulonicigenium:

Ketogulonicigenium vulgare

Industrial application:

Physical Properties

State

Solid

Experimental Properties

Property	Value	Reference
Melting Point	191 °C	PhysProp
Boiling Point	Not Available	Not Available
Water Solubility	400 mg/mL at 40 °C	MERCK INDEX (1996)
logP	-1.85	AVDEEF,A (1997)

Predicted Properties

Property	Value	Source
logP	-1.6	ALOGPS
logP	-1.9	ChemAxon
logS	0.14	ALOGPS
pKa (Strongest Acidic)	4.36	ChemAxon
pKa (Strongest Basic)	-3	ChemAxon
Physiological Charge	-1	ChemAxon
Hydrogen Acceptor Count	5	ChemAxon
Hydrogen Donor Count	4	ChemAxon
Polar Surface Area	107.22 Å²	ChemAxon
Rotatable Bond Count	2	ChemAxon
Refractivity	37.03 m³·mol⁻¹	ChemAxon
Polarizability	14.93 Å³	ChemAxon
Number of Rings	1	ChemAxon
Bioavailability	Yes	ChemAxon
Rule of Five	Yes	ChemAxon
Ghose Filter	No	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	No	ChemAxon

Spectra

EI-MS/GC-MS

Type	Description	Splash Key	View
GC-MS	Ascorbic acid, non-derivatized, GC-MS Spectrum	splash10-004i-4900000000-e99089fd55560fb70cfe	Spectrum
GC-MS	Ascorbic acid, non-derivatized, GC-MS Spectrum	splash10-0002-0912000000-baa8cffda0478e1bc197	Spectrum
GC-MS	Ascorbic acid, non-derivatized, GC-MS Spectrum	splash10-00di-9400000000-8ff8f48bfa2dd4fd3cf5	Spectrum
GC-MS	Ascorbic acid, non-derivatized, GC-MS Spectrum	splash10-00di-9400000000-c1dc72c6cbc49fbf3454	Spectrum
GC-MS	Ascorbic acid, non-derivatized, GC-MS Spectrum	splash10-00di-9400000000-b207f4024993c5a74769	Spectrum
GC-MS	Ascorbic acid, non-derivatized, GC-MS Spectrum	splash10-0002-0911000000-9af0c08e85e0c51a25c4	Spectrum
GC-MS	Ascorbic acid, non-derivatized, GC-MS Spectrum	splash10-004i-4900000000-e99089fd55560fb70cfe	Spectrum
GC-MS	Ascorbic acid, non-derivatized, GC-MS Spectrum	splash10-0002-0912000000-baa8cffda0478e1bc197	Spectrum
GC-MS	Ascorbic acid, non-derivatized, GC-MS Spectrum	splash10-00di-9400000000-8ff8f48bfa2dd4fd3cf5	Spectrum
GC-MS	Ascorbic acid, non-derivatized, GC-MS Spectrum	splash10-00di-9400000000-c1dc72c6cbc49fbf3454	Spectrum
GC-MS	Ascorbic acid, non-derivatized, GC-MS Spectrum	splash10-00di-9400000000-b207f4024993c5a74769	Spectrum
GC-MS	Ascorbic acid, non-derivatized, GC-MS Spectrum	splash10-0002-0911000000-9af0c08e85e0c51a25c4	Spectrum
Predicted GC-MS	Ascorbic acid, non-derivatized, Predicted GC-MS Spectrum - 70eV, Positive	splash10-0560-9700000000-ab53eee999ee7fee672d	Spectrum
Predicted GC-MS	Ascorbic acid, 4 TMS, Predicted GC-MS Spectrum - 70eV, Positive	splash10-0kkj-9357500000-5c2c439f726b729dd50d	Spectrum
Predicted GC-MS	Ascorbic acid, non-derivatized, Predicted GC-MS Spectrum - 70eV, Positive	Not Available	Spectrum
Predicted GC-MS	Ascorbic acid, non-derivatized, Predicted GC-MS Spectrum - 70eV, Positive	Not Available	Spectrum
Predicted GC-MS	Ascorbic acid, TMS_1_1, Predicted GC-MS Spectrum - 70eV, Positive	Not Available	Spectrum
Predicted GC-MS	Ascorbic acid, TMS_1_2, Predicted GC-MS Spectrum - 70eV, Positive	Not Available	Spectrum
Predicted GC-MS	Ascorbic acid, TMS_1_3, Predicted GC-MS Spectrum - 70eV, Positive	Not Available	Spectrum
Predicted GC-MS	Ascorbic acid, TMS_1_4, Predicted GC-MS Spectrum - 70eV, Positive	Not Available	Spectrum
Predicted GC-MS	Ascorbic acid, TMS_2_1, Predicted GC-MS Spectrum - 70eV, Positive	Not Available	Spectrum
Predicted GC-MS	Ascorbic acid, TMS_2_2, Predicted GC-MS Spectrum - 70eV, Positive	Not Available	Spectrum
Predicted GC-MS	Ascorbic acid, TMS_2_3, Predicted GC-MS Spectrum - 70eV, Positive	Not Available	Spectrum
Predicted GC-MS	Ascorbic acid, TMS_2_4, Predicted GC-MS Spectrum - 70eV, Positive	Not Available	Spectrum
Predicted GC-MS	Ascorbic acid, TMS_2_5, Predicted GC-MS Spectrum - 70eV, Positive	Not Available	Spectrum

MS/MS

Type	Description	Splash Key	View
MS/MS	LC-MS/MS Spectrum - NA , positive	splash10-0002-9300000000-d8c8254ad1dd4de2674c	2020-07-21	View Spectrum
MS/MS	LC-MS/MS Spectrum - LC-ESI-QTOF 35V, positive	splash10-004i-1900000000-da5bc92501d37735007f	2020-07-21	View Spectrum
MS/MS	LC-MS/MS Spectrum - NA , positive	splash10-0006-0900000000-b653774b8718c29fe97a	2020-07-21	View Spectrum
MS/MS	LC-MS/MS Spectrum - LC-ESI-QFT , negative	splash10-000i-9200000000-5d1ea04ef6404f5ecf7c	2020-07-21	View Spectrum
MS/MS	LC-MS/MS Spectrum - LC-ESI-QTOF 35V, negative	splash10-000i-9000000000-0371d7191fa8a89176f3	2020-07-21	View Spectrum
MS/MS	LC-MS/MS Spectrum - QqQ 6V, negative	splash10-004i-0900000000-76825c62319d5f4cbed9	2020-07-21	View Spectrum
MS/MS	LC-MS/MS Spectrum - QqQ 10V, negative	splash10-016r-2900000000-700d5d6247efb36c48d7	2020-07-21	View Spectrum
MS/MS	LC-MS/MS Spectrum - QqQ 13V, negative	splash10-014i-8900000000-4d76fc951d56a75a025e	2020-07-21	View Spectrum
MS/MS	LC-MS/MS Spectrum - QqQ 16V, negative	splash10-05tr-9300000000-0967cf71e141f71c2e00	2020-07-21	View Spectrum
MS/MS	LC-MS/MS Spectrum - QqQ 20V, negative	splash10-052r-9100000000-2bca6a943255612f1e7d	2020-07-21	View Spectrum
MS/MS	LC-MS/MS Spectrum - n/a 12V, negative	splash10-000i-9000000000-804b40cc657a43d298fb	2020-07-22	View Spectrum
MS/MS	LC-MS/MS Spectrum - n/a 12V, negative	splash10-0a4i-9000000000-cad0cc415c906a783cfc	2020-07-22	View Spectrum
MS/MS	LC-MS/MS Spectrum - n/a 12V, negative	splash10-0a4r-9000000000-f79a7dfc866621b3c926	2020-07-22	View Spectrum
MS/MS	LC-MS/MS Spectrum - Orbitrap 2V, negative	splash10-004i-0900000000-707796161cd4fae98f67	2020-07-22	View Spectrum
MS/MS	LC-MS/MS Spectrum - Orbitrap 2V, negative	splash10-004i-0900000000-035a78987127cc9f23f5	2020-07-22	View Spectrum
MS/MS	LC-MS/MS Spectrum - Orbitrap 2V, negative	splash10-004i-0900000000-dac785ef05051971e946	2020-07-22	View Spectrum
MS/MS	LC-MS/MS Spectrum - Orbitrap 3V, negative	splash10-00or-1900000000-a91dc1a29cb724a17811	2020-07-22	View Spectrum
MS/MS	LC-MS/MS Spectrum - Orbitrap 4V, negative	splash10-016r-3900000000-78f1f46067d2459f17c7	2020-07-22	View Spectrum
MS/MS	LC-MS/MS Spectrum - Orbitrap 5V, negative	splash10-014i-6900000000-8044f242bb90f54a595a	2020-07-22	View Spectrum
Predicted MS/MS	Predicted LC-MS/MS Spectrum - 10V, Positive	splash10-0kdi-2900000000-f05a720e6e6361c97e5f	2016-08-03	View Spectrum
Predicted MS/MS	Predicted LC-MS/MS Spectrum - 20V, Positive	splash10-0bvl-5900000000-6ca3f37a74403d8495c9	2016-08-03	View Spectrum
Predicted MS/MS	Predicted LC-MS/MS Spectrum - 40V, Positive	splash10-0a4i-9100000000-5625440c512f60760fdf	2016-08-03	View Spectrum
Predicted MS/MS	Predicted LC-MS/MS Spectrum - 10V, Negative	splash10-0o90-2900000000-b7c897849334927f5bf5	2016-08-03	View Spectrum
Predicted MS/MS	Predicted LC-MS/MS Spectrum - 20V, Negative	splash10-0bvi-4900000000-1f1fa10e7e06a79c028a	2016-08-03	View Spectrum
Predicted MS/MS	Predicted LC-MS/MS Spectrum - 40V, Negative	splash10-08fu-9300000000-b98375c0cd3a54b61ef7	2016-08-03	View Spectrum

NMR

Not Available

Pathways

Name	SMPDB/Pathwhiz	KEGG
Catecholamine Biosynthesis
Carnitine Synthesis		Not Available
Aromatic L-Aminoacid Decarboxylase Deficiency		Not Available
Tyrosine hydroxylase deficiency		Not Available
Phytanic Acid Peroxisomal Oxidation		Not Available

Protein Targets

Enzymes

Protein Name	Gene Name	Locus	Uniprot ID	Details
Peptidyl-glycine alpha-amidating monooxygenase	PAM	5q14-q21	P19021	details
Dopamine beta-hydroxylase	DBH	9q34	P09172	details
Phytanoyl-CoA dioxygenase, peroxisomal	PHYH	10p13	O14832	details
Prolyl 4-hydroxylase subunit alpha-2	P4HA2	5q31	O15460	details
Prolyl 4-hydroxylase subunit alpha-1	P4HA1	10q21.3-q23.1	P13674	details
Lactase-phlorizin hydrolase	LCT	2q21	P09848	details
Gamma-butyrobetaine dioxygenase	BBOX1	11p14.2	O75936	details
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1	PLOD1	1p36.22	Q02809	details
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2	PLOD2	3q24	O00469	details
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3	PLOD3	7q22	O60568	details
Glutathione S-transferase omega-1	GSTO1	10q25.1	P78417	details
Glutathione S-transferase omega-2	GSTO2	10q25.1	Q9H4Y5	details
Protein disulfide-isomerase	P4HB	17q25	P07237	details
Trimethyllysine dioxygenase, mitochondrial	TMLHE	Xq28	Q9NVH6	details
Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2	ALKBH2	12q24.11	Q6NS38	details
Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3	ALKBH3	11p11.2	Q96Q83	details
Prolyl 3-hydroxylase 1	LEPRE1	1p34.1	Q32P28	details
Prolyl 3-hydroxylase 2	LEPREL1	3q28	Q8IVL5	details
Prolyl 3-hydroxylase 3	LEPREL2	12q13	Q8IVL6	details
Prolyl 4-hydroxylase subunit alpha-3	P4HA3	11q13.4	Q7Z4N8	details
Egl nine homolog 1	EGLN1	1q42.1	Q9GZT9	details
Egl nine homolog 2	EGLN2	19q13.2	Q96KS0	details
Egl nine homolog 3	EGLN3	14q13.1	Q9H6Z9	details
Transmembrane prolyl 4-hydroxylase	P4HTM	3p21.3	Q9NXG6	details
2-oxoglutarate and iron-dependent oxygenase domain-containing protein 1	OGFOD1	16q12.2	Q8N543	details
2-oxoglutarate and iron-dependent oxygenase domain-containing protein 2	OGFOD2	12q24.31	Q6N063	details

Transporters

Protein Name	Gene Name	Locus	Uniprot ID	Details
Solute carrier family 23 member 1	SLC23A1	5q31.2	Q9UHI7	details
Solute carrier family 23 member 2	SLC23A2	20p13	Q9UGH3	details
Solute carrier family 23 member 3	SLC23A3	2q35	Q6PIS1	details

Metal Bindings

Protein Name	Gene Name	Locus	Uniprot ID	Details
Peptidyl-glycine alpha-amidating monooxygenase	PAM	5q14-q21	P19021	details
Dopamine beta-hydroxylase	DBH	9q34	P09172	details
Phytanoyl-CoA dioxygenase, peroxisomal	PHYH	10p13	O14832	details
Prolyl 4-hydroxylase subunit alpha-2	P4HA2	5q31	O15460	details
Prolyl 4-hydroxylase subunit alpha-1	P4HA1	10q21.3-q23.1	P13674	details
Gamma-butyrobetaine dioxygenase	BBOX1	11p14.2	O75936	details
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1	PLOD1	1p36.22	Q02809	details
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2	PLOD2	3q24	O00469	details
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3	PLOD3	7q22	O60568	details
Trimethyllysine dioxygenase, mitochondrial	TMLHE	Xq28	Q9NVH6	details
Prolyl 3-hydroxylase 1	LEPRE1	1p34.1	Q32P28	details
Prolyl 3-hydroxylase 2	LEPREL1	3q28	Q8IVL5	details
Prolyl 3-hydroxylase 3	LEPREL2	12q13	Q8IVL6	details
Prolyl 4-hydroxylase subunit alpha-3	P4HA3	11q13.4	Q7Z4N8	details
Egl nine homolog 1	EGLN1	1q42.1	Q9GZT9	details
Egl nine homolog 2	EGLN2	19q13.2	Q96KS0	details
Egl nine homolog 3	EGLN3	14q13.1	Q9H6Z9	details
Transmembrane prolyl 4-hydroxylase	P4HTM	3p21.3	Q9NXG6	details
2-oxoglutarate and iron-dependent oxygenase domain-containing protein 1	OGFOD1	16q12.2	Q8N543	details
2-oxoglutarate and iron-dependent oxygenase domain-containing protein 2	OGFOD2	12q24.31	Q6N063	details

Receptors

Protein Name	Gene Name	Locus	Uniprot ID	Details
Egl nine homolog 2	EGLN2	19q13.2	Q96KS0	details

Transcriptional Factors

Protein Name	Gene Name	Locus	Uniprot ID	Details
Egl nine homolog 1	EGLN1	1q42.1	Q9GZT9	details
Egl nine homolog 2	EGLN2	19q13.2	Q96KS0	details
Egl nine homolog 3	EGLN3	14q13.1	Q9H6Z9	details

Concentrations Data

Not Available

External Links

HMDB ID

HMDB0014273

DrugBank ID

DB00126

Phenol Explorer Compound ID

Not Available

FoodDB ID

KNApSAcK ID

Chemspider ID

KEGG Compound ID

BioCyc ID

BiGG ID

Not Available

Wikipedia Link

Ascorbic_Acid

METLIN ID

Not Available

PubChem Compound

Not Available

PDB ID

Not Available

ChEBI ID

29073

References

General References

Not Available

Only showing the first 10 proteins. There are 53 proteins in total.

Show All

Enzymes

Enzyme Details

1. Peptidyl-glycine alpha-amidating monooxygenase

General function:: Involved in monooxygenase activity
Specific function:: Bifunctional enzyme that catalyzes 2 sequential steps in C-terminal alpha-amidation of peptides. The monooxygenase part produces an unstable peptidyl(2-hydroxyglycine) intermediate that is dismutated to glyoxylate and the corresponding desglycine peptide amide by the lyase part. C-terminal amidation of peptides such as neuropeptides is essential for full biological activity.
Gene Name:: PAM
Uniprot ID:: P19021
Molecular weight:: 108402.425

Enzyme Details

2. Dopamine beta-hydroxylase

General function:: Involved in monooxygenase activity
Specific function:: Conversion of dopamine to noradrenaline.
Gene Name:: DBH
Uniprot ID:: P09172
Molecular weight:: 69064.45

Enzyme Details

3. Phytanoyl-CoA dioxygenase, peroxisomal

General function:: Involved in electron carrier activity
Specific function:: Converts phytanoyl-CoA to 2-hydroxyphytanoyl-CoA.
Gene Name:: PHYH
Uniprot ID:: O14832
Molecular weight:: 38538.065

Enzyme Details

4. Prolyl 4-hydroxylase subunit alpha-2

General function:: Involved in oxidoreductase activity
Specific function:: Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
Gene Name:: P4HA2
Uniprot ID:: O15460
Molecular weight:: 60632.19

Enzyme Details

5. Prolyl 4-hydroxylase subunit alpha-1

General function:: Involved in oxidoreductase activity
Specific function:: Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
Gene Name:: P4HA1
Uniprot ID:: P13674
Molecular weight:: 60966.645

Enzyme Details

6. Lactase-phlorizin hydrolase

General function:: Involved in hydrolase activity, hydrolyzing O-glycosyl compounds
Specific function:: LPH splits lactose in the small intestine.
Gene Name:: LCT
Uniprot ID:: P09848
Molecular weight:: 218584.77

Enzyme Details

7. Gamma-butyrobetaine dioxygenase

General function:: Involved in iron ion binding
Specific function:: Catalyzes the formation of L-carnitine from gamma-butyrobetaine.
Gene Name:: BBOX1
Uniprot ID:: O75936
Molecular weight:: 44714.6

Enzyme Details

8. Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1

General function:: Involved in oxidoreductase activity
Specific function:: Forms hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens. These hydroxylysines serve as sites of attachment for carbohydrate units and are essential for the stability of the intermolecular collagen cross-links.
Gene Name:: PLOD1
Uniprot ID:: Q02809
Molecular weight:: 83549.55

Enzyme Details

9. Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2

General function:: Involved in oxidoreductase activity
Specific function:: Forms hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens. These hydroxylysines serve as sites of attachment for carbohydrate units and are essential for the stability of the intermolecular collagen cross-links.
Gene Name:: PLOD2
Uniprot ID:: O00469
Molecular weight:: 84685.07

Enzyme Details

10. Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3

General function:: Involved in oxidoreductase activity
Specific function:: Forms hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens. These hydroxylysines serve as sites of attachment for carbohydrate units and are essential for the stability of the intermolecular collagen cross-links.
Gene Name:: PLOD3
Uniprot ID:: O60568
Molecular weight:: 84784.505

Transporters

Enzyme Details

1. Solute carrier family 23 member 1

General function:: Involved in transporter activity
Specific function:: Sodium/ascorbate cotransporter. Mediates electrogenic uptake of vitamin C, with a stoichiometry of 2 Na(+) for each ascorbate
Gene Name:: SLC23A1
Uniprot ID:: Q9UHI7
Molecular weight:: 64830.4

Enzyme Details

2. Solute carrier family 23 member 2

General function:: Nucleotide transport and metabolism
Specific function:: Sodium/ascorbate cotransporter. Mediates electrogenic uptake of vitamin C, with a stoichiometry of 2 Na(+) for each ascorbate
Gene Name:: SLC23A2
Uniprot ID:: Q9UGH3
Molecular weight:: 70336.2

Enzyme Details

3. Solute carrier family 23 member 3

General function:: Involved in transporter activity
Specific function:: Not Available
Gene Name:: SLC23A3
Uniprot ID:: Q6PIS1
Molecular weight:: 64529.9

Only showing the first 10 proteins. There are 53 proteins in total.

Show All

Showing Compound Card for Ascorbic acid (CDB004789)

Structure for CDB004789 (Ascorbic acid)

Enzymes

Transporters