Identification |
HMDB Protein ID
| CDBP02265 |
Secondary Accession Numbers
| Not Available |
Name
| Solute carrier family 23 member 2 |
Description
| Not Available |
Synonyms
|
- Na(+)/L-ascorbic acid transporter 2
- Nucleobase transporter-like 1 protein
- Sodium-dependent vitamin C transporter 2
- Yolk sac permease-like molecule 2
- hSVCT2
|
Gene Name
| SLC23A2 |
Protein Type
| Transporter |
Biological Properties |
General Function
| Nucleotide transport and metabolism |
Specific Function
| Sodium/ascorbate cotransporter. Mediates electrogenic uptake of vitamin C, with a stoichiometry of 2 Na(+) for each ascorbate |
GO Classification
|
Component |
membrane |
cell part |
Function |
transporter activity |
Process |
establishment of localization |
transport |
transmembrane transport |
|
Cellular Location
|
- Membrane
- Multi-pass membrane protein
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Chromosome:2 |
Locus
| 20p13 |
SNPs
| SLC23A2 |
Gene Sequence
|
>1953 bp
ATGATGGGTATTGGTAAGAATACCACATCCAAATCAATGGAGGCTGGAAGTTCAACAGAA
GGCAAATACGAAGACGAGGCAAAGCACCCAGCTTTCTTCACTCTTCCGGTGGTGATAAAT
GGAGGCGCCACCTCCAGCGGTGAGCAGGACAATGAGGACACTGAGCTCATGGCGATCTAC
ACTACGGAAAACGGCATTGCAGAAAAGAGCTCTCTCGCTGAGACCCTGGATAGCACTGGC
AGTCTGGACCCCCAGCGATCAGACATGATTTATACCATAGAAGATGTTCCTCCCTGGTAC
CTGTGTATATTTCTGGGGCTACAGCACTACCTGACATGCTTCAGCGGCACGATCGCAGTG
CCCTTCCTGTTGGCCGATGCCATGTGTGTGGGGTACGACCAGTGGGCCACCAGCCAGCTC
ATTGGGACCATTTTCTTCTGTGTGGGAATCACTACTTTGCTACAGACAACGTTTGGATGC
AGGTTACCCCTGTTTCAGACCAGTGCTTTTGCATTTTTGGCCCCTGCTCGAGCCATCCTG
TCTTTAGATAAATGGAAATGTAACACCACAGATGTTTCAGTTGCCAATGGAACAGCAGAG
CTGTTGCACACAGAACACATCTGGTATCCCCGGATCCGAGAGATCCAGGGGGCCATCATC
ATGTCCTCACTGATAGAAGTAGTCATCGGCCTCCTCGGCCTGCCTGGGGCTCTACTGAAG
TACATCGGTCCCTTGACCATTACACCCACGGTGGCCCTAATTGGCCTCTCTGGTTTCCAG
GCAGCGGGGGAGAGAGCCGGGAAGCACTGGGGCATTGCCATGCTGACAATATTCCTAGTA
TTACTGTTTTCTCAATACGCCAGAAATGTTAAATTTCCTCTCCCGATTTATAAATCCAAG
AAAGGATGGACTGCGTACAAGTTACAGCTGTTCAAAATGTTCCCTATCATCCTGGCCATC
CTGGTATCCTGGCTGCTCTGCTTCATCTTCACGGTGACAGATGTCTTCCCTCCCGACAGC
ACAAAGTATGGCTTCTATGCTCGCACAGATGCCAGGCAAGGCGTGCTTCTGGTAGCCCCG
TGGTTTAAGGTTCCATACCCATTTCAGTGGGGACTGCCCACCGTGTCTGCGGCCGGTGTC
ATCGGCATGCTCAGTGCCGTGGTCGCCAGCATCATCGAGTCTATTGGTGACTACTACGCC
TGTGCACGGCTGTCCTGTGCCCCACCCCCCCCCATCCACGCAATAAACAGGGGAATTTTC
GTGGAAGGCCTCTCCTGTGTTCTTGATGGCATATTTGGTACTGGGAATGGCTCTACTTCA
TCCAGTCCCAACATTGGAGTTTTGGGAATTACAAAGGTCGGCAGCCGCCGCGTGATACAG
TGCGGAGCAGCCCTCATGCTCGCTCTGGGCATGATCGGGAAGTTCAGCGCCCTCTTTGCG
TCCCTTCCGGATCCTGTGCTGGGAGCCCTGTTCTGCACGCTCTTTGGAATGATCACAGCT
GTTGGCCTCTCTAACCTGCAGTTCATTGATTTAAATTCTTCCCGGAACCTCTTTGTGCTT
GGATTTTCGATCTTCTTTGGGCTCGTCCTTCCAAGTTACCTCAGACAGAACCCTCTGGTC
ACAGGGATAACAGGAATCGATCAAGTGTTGAACGTCCTTCTCACAACTGCTATGTTTGTA
GGGGGCTGTGTGGCTTTTATCCTGGATAACACCATCCCAGGCACTCCAGAGGAAAGAGGA
ATCCGGAAATGGAAGAAGGGTGTGGGCAAAGGGAACAAATCACTCGACGGCATGGAGTCG
TACAATTTGCCATTTGGCATGAACATTATAAAAAAATACAGATGCTTCAGCTACTTACCC
ATCAGCCCAACCTTTGTGGGCTACACATGGAAAGGCCTCAGGAAGAGCGACAACAGCCGG
AGTTCAGATGAAGACTCCCAGGCCACGGGATAG
|
Protein Properties |
Number of Residues
| 650 |
Molecular Weight
| 70336.2 |
Theoretical pI
| 7.74 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
- ["103-123", "140-160", "162-182", "219-239", "242-262", "267-287", "313-333", "372-392", "462-482", "486-506", "514-534", "548-568"]
|
Protein Sequence
|
>Solute carrier family 23 member 2
MMGIGKNTTSKSMEAGSSTEGKYEDEAKHPAFFTLPVVINGGATSSGEQDNEDTELMAIY
TTENGIAEKSSLAETLDSTGSLDPQRSDMIYTIEDVPPWYLCIFLGLQHYLTCFSGTIAV
PFLLADAMCVGYDQWATSQLIGTIFFCVGITTLLQTTFGCRLPLFQASAFAFLAPARAIL
SLDKWKCNTTDVSVANGTAELLHTEHIWYPRIREIQGAIIMSSLIEVVIGLLGLPGALLK
YIGPLTITPTVALIGLSGFQAAGERAGKHWGIAMLTIFLVLLFSQYARNVKFPLPIYKSK
KGWTAYKLQLFKMFPIILAILVSWLLCFIFTVTDVFPPDSTKYGFYARTDARQGVLLVAP
WFKVPYPFQWGLPTVSAAGVIGMLSAVVASIIESIGDYYACARLSCAPPPPIHAINRGIF
VEGLSCVLDGIFGTGNGSTSSSPNIGVLGITKVGSRRVIQCGAALMLALGMIGKFSALFA
SLPDPVLGALFCTLFGMITAVGLSNLQFIDLNSSRNLFVLGFSIFFGLVLPSYLRQNPLV
TGITGIDQVLNVLLTTAMFVGGCVAFILDNTIPGTPEERGIRKWKKGVGKGNKSLDGMES
YNLPFGMNIIKKYRCFSYLPISPTFVGYTWKGLRKSDNSRSSDEDSQATG
|
External Links |
GenBank ID Protein
| 3789789 |
UniProtKB/Swiss-Prot ID
| Q9UGH3 |
UniProtKB/Swiss-Prot Entry Name
| S23A2_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| AF058319 |
GeneCard ID
| SLC23A2 |
GenAtlas ID
| Not Available |
HGNC ID
| Not Available |
References |
General References
| Not Available |