Cannabis Compound Database: Showing Compound Card for Glycerol 3-phosphate (CDB004806)

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Record Information

Version

1.0

Created at

2020-04-17 18:38:41 UTC

Updated at

2020-12-07 19:10:59 UTC

CannabisDB ID

CDB004806

Secondary Accession Numbers

Not Available

Cannabis Compound Identification

Common Name

Glycerol 3-phosphate

Description

Glycerol 3-phosphate, also known as glycerophosphoric acid or sn-gro-1-p, belongs to the class of organic compounds known as glycerophosphates. Glycerophosphates are compounds containing a glycerol linked to a phosphate group. Glycerol 3-phosphate is an extremely weak basic (essentially neutral) compound (based on its pKa). Glycerol 3-phosphate is expected to be in Cannabis as all living plants are known to produce and metabolize it.

Structure

MOL SDF 3D-SDF PDB SMILES InChI View 3D Structure

Synonyms

Value	Source
(R)-Glycerol 1-phosphate	ChEBI
D-(Glycerol 1-phosphate)	ChEBI
D-Glycerol 1-phosphate	ChEBI
Glycerol-3-phosphate	ChEBI
Glycerophosphoric acid	ChEBI
L-(Glycerol 3-phosphate)	ChEBI
Phosphoric acid mono-((R)-2,3-dihydroxy-propyl) ester	ChEBI
Phosphorsaeure-mono-((R)-2,3-dihydroxy-propylester)	ChEBI
sn-GLYCEROL-3-phosphATE	ChEBI
sn-Gro-1-p	ChEBI
(R)-Glycerol 1-phosphoric acid	Generator
D-(Glycerol 1-phosphoric acid)	Generator
D-Glycerol 1-phosphoric acid	Generator
Glycerol-3-phosphoric acid	Generator
Glycerophosphate	Generator
L-(Glycerol 3-phosphoric acid)	Generator
Phosphate mono-((R)-2,3-dihydroxy-propyl) ester	Generator
sn-GLYCEROL-3-phosphoric acid	Generator
Glycerol 3-phosphoric acid	Generator
1-(Dihydrogen phosphate) glycerol	HMDB
1-Glycerophosphate	HMDB
1-Glycerophosphorate	HMDB
1-Glycerophosphoric acid	HMDB
3-Glycerophosphate	HMDB
a-Glycerophosphate	HMDB
a-Glycerophosphorate	HMDB
a-Glycerophosphoric acid	HMDB
a-Phosphoglycerol	HMDB
alpha-Glycerophosphate	HMDB
alpha-Glycerophosphorate	HMDB
alpha-Glycerophosphoric acid	HMDB
alpha-Phosphoglycerol	HMDB
Dihydrogen a-glycerophosphate	HMDB
DL-a-Glycerol phosphate	HMDB
DL-a-Glycerophosphate	HMDB
DL-a-Glycerophosphorate	HMDB
DL-a-Glycerophosphoric acid	HMDB
DL-a-Glyceryl phosphate	HMDB
DL-alpha-Glycerol phosphate	HMDB
DL-alpha-Glycerophosphate	HMDB
DL-alpha-Glycerophosphorate	HMDB
DL-alpha-Glycerophosphoric acid	HMDB
DL-alpha-Glyceryl phosphate	HMDB
DL-Glycerol 1-phosphate	HMDB
DL-Glycerol 3-phosphate	HMDB
Glycerol 1-phosphate	HMDB
Glycerol a-phosphate	HMDB
Glycerol monophosphate	HMDB
Glycerophosphorate	HMDB
Glycerophosphoric acid I	HMDB
Glyceryl phosphate	HMDB
sn-Glycerol 3-phosphate	HMDB
1-Phosphoglycerol	HMDB
alpha-Glycerophosphoric acid, (DL)-isomer	HMDB
alpha-Glycerophosphoric acid, (R)-isomer	HMDB
alpha-Glycerophosphoric acid, (S)-isomer	HMDB
alpha-Glycerophosphoric acid, 1,2,3-propanetriol-1-(18)O,3-(dihydrogen phosphate)-labeled	HMDB
alpha-Glycerophosphoric acid, 1,2,3-propanetriol-2-(18)O,3-(dihydrogen phosphate)-labeled	HMDB
alpha-Glycerophosphoric acid, fe salt	HMDB
alpha-Glycerophosphoric acid, fe(+3) salt (3:2)	HMDB
alpha-Glycerophosphoric acid, calcium salt	HMDB
alpha-Glycerophosphoric acid, disodium salt	HMDB
alpha-Glycerophosphoric acid, disodium salt (+-)-isomer	HMDB
alpha-Glycerophosphoric acid, disodium salt hexahydrate(+-)-isomer	HMDB
alpha-Glycerophosphoric acid, monocalcium salt	HMDB
alpha-Glycerophosphoric acid, monocalcium salt (S)-isomer	HMDB
alpha-Glycerophosphoric acid, monomagnesium salt	HMDB
alpha-Glycerophosphoric acid, sodium salt	HMDB
Disodium glycerophosphate	HMDB
Sodium glycerophosphate	HMDB

Chemical Formula

C₃H₉O₆P

Average Molecular Weight

172.07

Monoisotopic Molecular Weight

172.0137

IUPAC Name

[(2R)-2,3-dihydroxypropoxy]phosphonic acid

Traditional Name

3-phosphoglycerol

CAS Registry Number

57-03-4

SMILES

OC[C@@H](O)COP(O)(O)=O

InChI Identifier

InChI=1S/C3H9O6P/c4-1-3(5)2-9-10(6,7)8/h3-5H,1-2H2,(H2,6,7,8)/t3-/m1/s1

InChI Key

AWUCVROLDVIAJX-GSVOUGTGSA-N

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as glycerophosphates. Glycerophosphates are compounds containing a glycerol linked to a phosphate group.

Kingdom

Organic compounds

Super Class

Lipids and lipid-like molecules

Class

Glycerophospholipids

Sub Class

Glycerophosphates

Direct Parent

Glycerophosphates

Alternative Parents

Substituents

Sn-glycerol-3-phosphate
Monoalkyl phosphate
Alkyl phosphate
Phosphoric acid ester
Organic phosphoric acid derivative
Secondary alcohol
1,2-diol
Organic oxygen compound
Organic oxide
Hydrocarbon derivative
Primary alcohol
Organooxygen compound
Alcohol
Aliphatic acyclic compound

Molecular Framework

Aliphatic acyclic compounds

External Descriptors

sn-glycerol 3-phosphates (CHEBI:15978 )
glycerol 1-phosphate (CHEBI:15978 )

Ontology

Physiological effect

Organoleptic effect:

Touch:

Smooth

Disposition

Route of exposure:

Enteral:

Ingestion

Source:

Biological location:

Tissue and substructures:

Placenta

Organ and components:

Prostate

Biofluid and excreta:

Subcellular:

Role

Biological role:

Industrial application:

Food and nutrition:

Pharmaceutical industry:

Pharmaceutical

Physical Properties

State

Solid

Experimental Properties

Property	Value	Reference
Melting Point	102 - 104 °C	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	1000 mg/mL	Not Available
logP	Not Available	Not Available

Predicted Properties

Property	Value	Source
logP	-1.8	ALOGPS
logP	-2	ChemAxon
logS	-0.75	ALOGPS
pKa (Strongest Acidic)	1.51	ChemAxon
pKa (Strongest Basic)	-3	ChemAxon
Physiological Charge	-2	ChemAxon
Hydrogen Acceptor Count	5	ChemAxon
Hydrogen Donor Count	4	ChemAxon
Polar Surface Area	107.22 Å²	ChemAxon
Rotatable Bond Count	4	ChemAxon
Refractivity	31.39 m³·mol⁻¹	ChemAxon
Polarizability	13.58 Å³	ChemAxon
Number of Rings	0	ChemAxon
Bioavailability	Yes	ChemAxon
Rule of Five	Yes	ChemAxon
Ghose Filter	No	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	No	ChemAxon

Spectra

EI-MS/GC-MS

Type	Description	Splash Key	View
GC-MS	Glycerol 3-phosphate, non-derivatized, GC-MS Spectrum	splash10-0uea-0932000000-726f422c76a193edf232	Spectrum
GC-MS	Glycerol 3-phosphate, non-derivatized, GC-MS Spectrum	splash10-0uea-0932000000-726f422c76a193edf232	Spectrum
GC-MS	Glycerol 3-phosphate, 4 TMS, GC-MS Spectrum	splash10-0zgj-1976000000-019de1fa6314b95ef7fe	Spectrum
Predicted GC-MS	Glycerol 3-phosphate, non-derivatized, Predicted GC-MS Spectrum - 70eV, Positive	splash10-01ot-9300000000-a435ec7fb966f8ddc1a2	Spectrum
Predicted GC-MS	Glycerol 3-phosphate, 2 TMS, Predicted GC-MS Spectrum - 70eV, Positive	splash10-0230-9080000000-9f48133c7a08fb549acd	Spectrum
Predicted GC-MS	Glycerol 3-phosphate, non-derivatized, Predicted GC-MS Spectrum - 70eV, Positive	Not Available	Spectrum
Predicted GC-MS	Glycerol 3-phosphate, non-derivatized, Predicted GC-MS Spectrum - 70eV, Positive	Not Available	Spectrum
Predicted GC-MS	Glycerol 3-phosphate, TMS_1_1, Predicted GC-MS Spectrum - 70eV, Positive	Not Available	Spectrum
Predicted GC-MS	Glycerol 3-phosphate, TMS_1_2, Predicted GC-MS Spectrum - 70eV, Positive	Not Available	Spectrum
Predicted GC-MS	Glycerol 3-phosphate, TMS_1_3, Predicted GC-MS Spectrum - 70eV, Positive	Not Available	Spectrum
Predicted GC-MS	Glycerol 3-phosphate, TMS_2_2, Predicted GC-MS Spectrum - 70eV, Positive	Not Available	Spectrum
Predicted GC-MS	Glycerol 3-phosphate, TMS_2_3, Predicted GC-MS Spectrum - 70eV, Positive	Not Available	Spectrum
Predicted GC-MS	Glycerol 3-phosphate, TMS_2_4, Predicted GC-MS Spectrum - 70eV, Positive	Not Available	Spectrum
Predicted GC-MS	Glycerol 3-phosphate, TBDMS_1_1, Predicted GC-MS Spectrum - 70eV, Positive	Not Available	Spectrum
Predicted GC-MS	Glycerol 3-phosphate, TBDMS_1_2, Predicted GC-MS Spectrum - 70eV, Positive	Not Available	Spectrum
Predicted GC-MS	Glycerol 3-phosphate, TBDMS_1_3, Predicted GC-MS Spectrum - 70eV, Positive	Not Available	Spectrum
Predicted GC-MS	Glycerol 3-phosphate, TBDMS_2_1, Predicted GC-MS Spectrum - 70eV, Positive	Not Available	Spectrum
Predicted GC-MS	Glycerol 3-phosphate, TBDMS_2_2, Predicted GC-MS Spectrum - 70eV, Positive	Not Available	Spectrum
Predicted GC-MS	Glycerol 3-phosphate, TBDMS_2_3, Predicted GC-MS Spectrum - 70eV, Positive	Not Available	Spectrum
Predicted GC-MS	Glycerol 3-phosphate, TBDMS_2_4, Predicted GC-MS Spectrum - 70eV, Positive	Not Available	Spectrum

MS/MS

Type	Description	Splash Key	View
MS/MS	LC-MS/MS Spectrum - Quattro_QQQ 10V, Positive (Annotated)	splash10-0002-9200000000-bf06c1d1e56cb8853243	2012-07-24	View Spectrum
MS/MS	LC-MS/MS Spectrum - Quattro_QQQ 25V, Positive (Annotated)	splash10-00kr-9200000000-ffce45222cab00a0c302	2012-07-24	View Spectrum
MS/MS	LC-MS/MS Spectrum - Quattro_QQQ 40V, Positive (Annotated)	splash10-001j-9000000000-7689cca8f9c9a12d9e75	2012-07-24	View Spectrum
MS/MS	LC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Positive	splash10-00di-0902000000-00e3a7e1ee10fbd8b03e	2012-08-31	View Spectrum
MS/MS	LC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Positive	splash10-000i-9000000000-1a40c90fd2eb656ddf5c	2012-08-31	View Spectrum
MS/MS	LC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Positive	splash10-0002-9000000000-f9bc5f552db38767c437	2012-08-31	View Spectrum
MS/MS	LC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Positive	splash10-0002-0920000000-72f8b96355726dd3a5b1	2012-08-31	View Spectrum
MS/MS	LC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Positive	splash10-00di-0901000000-2c3a8ed438d7ca0fa049	2012-08-31	View Spectrum
MS/MS	LC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Positive	splash10-000i-9000000000-a3549fb5ec2675fbf615	2012-08-31	View Spectrum
MS/MS	LC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Positive	splash10-0002-9000000000-096e2ba9a6ef6fd20d88	2012-08-31	View Spectrum
MS/MS	LC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Positive	splash10-0002-0930000000-171708905bad289d6031	2012-08-31	View Spectrum
MS/MS	LC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Negative	splash10-00di-0925110000-c1ced10d34f533b3fa1f	2012-08-31	View Spectrum
MS/MS	LC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Negative	splash10-03di-0900000000-4ee8a36492a451beda75	2012-08-31	View Spectrum
MS/MS	LC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Negative	splash10-004i-9000000000-de2aacfb81476c7755e5	2012-08-31	View Spectrum
MS/MS	LC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Negative	splash10-00di-0900000000-dd342482ade09e9ce749	2012-08-31	View Spectrum
MS/MS	LC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Negative	splash10-0fkc-0917520000-d61e6034525ac5f7588d	2012-08-31	View Spectrum
MS/MS	LC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Negative	splash10-004i-9000000000-d537d3f23f3d9a789c20	2012-08-31	View Spectrum
MS/MS	LC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Negative	splash10-00di-0900000000-2f1ca45b50402f6e62df	2012-08-31	View Spectrum
MS/MS	LC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Negative	splash10-0udi-0009000000-5606781224d6ab5caed3	2012-08-31	View Spectrum
MS/MS	LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 10V, Positive	splash10-0pi0-1900000000-75b6ed57a4c9cd6378b4	2012-08-31	View Spectrum
MS/MS	LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 20V, Positive	splash10-0a59-6900000000-1c46fbda1468f6fd803c	2012-08-31	View Spectrum
MS/MS	LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 30V, Positive	splash10-0a5c-9400000000-305e9a2554d8c3274f32	2012-08-31	View Spectrum
MS/MS	LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 40V, Positive	splash10-007o-9000000000-d11ad04a048c3dca25de	2012-08-31	View Spectrum
MS/MS	LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 50V, Positive	splash10-00mo-9000000000-7b779b4be184b5b26b6a	2012-08-31	View Spectrum
Predicted MS/MS	Predicted LC-MS/MS Spectrum - 10V, Positive	splash10-00di-5900000000-297dbde751110233eca5	2016-09-12	View Spectrum

NMR

Type	Description	View
1D NMR	¹H NMR Spectrum (1D, 600 MHz, H₂O, experimental)	Spectrum
1D NMR	¹H NMR Spectrum (1D, 100 MHz, D₂O, predicted)	Spectrum
1D NMR	¹³C NMR Spectrum (1D, 100 MHz, D₂O, predicted)	Spectrum
1D NMR	¹H NMR Spectrum (1D, 200 MHz, D₂O, predicted)	Spectrum
1D NMR	¹³C NMR Spectrum (1D, 200 MHz, D₂O, predicted)	Spectrum
1D NMR	¹H NMR Spectrum (1D, 300 MHz, D₂O, predicted)	Spectrum
1D NMR	¹³C NMR Spectrum (1D, 300 MHz, D₂O, predicted)	Spectrum
1D NMR	¹H NMR Spectrum (1D, 400 MHz, D₂O, predicted)	Spectrum
1D NMR	¹³C NMR Spectrum (1D, 400 MHz, D₂O, predicted)	Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, D₂O, predicted)	Spectrum
1D NMR	¹³C NMR Spectrum (1D, 500 MHz, D₂O, predicted)	Spectrum
1D NMR	¹H NMR Spectrum (1D, 600 MHz, D₂O, predicted)	Spectrum
1D NMR	¹³C NMR Spectrum (1D, 600 MHz, D₂O, predicted)	Spectrum
1D NMR	¹H NMR Spectrum (1D, 700 MHz, D₂O, predicted)	Spectrum
1D NMR	¹³C NMR Spectrum (1D, 700 MHz, D₂O, predicted)	Spectrum
1D NMR	¹H NMR Spectrum (1D, 800 MHz, D₂O, predicted)	Spectrum
1D NMR	¹³C NMR Spectrum (1D, 800 MHz, D₂O, predicted)	Spectrum
1D NMR	¹H NMR Spectrum (1D, 900 MHz, D₂O, predicted)	Spectrum
1D NMR	¹³C NMR Spectrum (1D, 900 MHz, D₂O, predicted)	Spectrum
1D NMR	¹H NMR Spectrum (1D, 1000 MHz, D₂O, predicted)	Spectrum
1D NMR	¹³C NMR Spectrum (1D, 1000 MHz, D₂O, predicted)	Spectrum
2D NMR	[¹H, ¹H]-TOCSY. Unexported temporarily by An Chi on Oct 15, 2021 until json or nmrML file is generated. 2D NMR Spectrum (experimental)	Spectrum
2D NMR	[¹H, ¹³C]-HSQC NMR Spectrum (2D, 600 MHz, H₂O, experimental)	Spectrum

Pathways

Name	SMPDB/Pathwhiz	KEGG
Glycerol Phosphate Shuttle		Not Available
Mitochondrial Electron Transport Chain
Phospholipid Biosynthesis
Glycerolipid Metabolism
Glycerol Kinase Deficiency		Not Available

Protein Targets

Enzymes

Protein Name	Gene Name	Locus	Uniprot ID	Details
Glycerol-3-phosphate dehydrogenase, mitochondrial	GPD2	2q24.1	P43304	details
Glycerol kinase 2	GK2	4q13	Q14410	details
Glycerol kinase	GK	Xp21.3	P32189	details
Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic	GPD1	12q12-q13	P21695	details
Glycerol-3-phosphate acyltransferase 1, mitochondrial	GPAM	10q25.2	Q9HCL2	details
Putative glycerol kinase 3	GK3P		Q14409	details
Glycerol-3-phosphate acyltransferase 4	AGPAT6	8p11.21	Q86UL3	details
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial	PGS1	17q25.3	Q32NB8	details
Glycerol-3-phosphate dehydrogenase 1-like protein	GPD1L	3p22.3	Q8N335	details
Glycerol-3-phosphate acyltransferase 3	AGPAT9	4q21.23	Q53EU6	details
Putative uncharacterized protein DKFZp451B1115	DKFZp451B1115		Q86T70	details
Glycerophosphodiester phosphodiesterase 1	GDE1	16p12-p11.2	Q9NZC3	details
Glycerol-3-phosphate acyltransferase 2, mitochondrial	GPAT2	2q11.1	Q6NUI2	details
Putative glycerol kinase 5	GK5	3q23	Q6ZS86	details
N-acetyltransferase ESCO1	ESCO1	18q11.2	Q5FWF5	details
Manganese-dependent ADP-ribose/CDP-alcohol diphosphatase	ADPRM	17p13.1	Q3LIE5	details
Glycerophosphocholine phosphodiesterase GPCPD1	GPCPD1	20p12.3	Q9NPB8	details

Transporters

Protein Name	Gene Name	Locus	Uniprot ID	Details
Glycerol-3-phosphate dehydrogenase 1-like protein	GPD1L	3p22.3	Q8N335	details

Metal Bindings

Protein Name	Gene Name	Locus	Uniprot ID	Details
Glycerol-3-phosphate dehydrogenase, mitochondrial	GPD2	2q24.1	P43304	details
Glycerophosphodiester phosphodiesterase 1	GDE1	16p12-p11.2	Q9NZC3	details
Manganese-dependent ADP-ribose/CDP-alcohol diphosphatase	ADPRM	17p13.1	Q3LIE5	details

Receptors

Not Available

Transcriptional Factors

Not Available

Concentrations Data

Not Available

External Links

HMDB ID

HMDB0000126

DrugBank ID

DB02515

Phenol Explorer Compound ID

Not Available

FoodDB ID

KNApSAcK ID

Chemspider ID

KEGG Compound ID

BioCyc ID

BiGG ID

Wikipedia Link

METLIN ID

PubChem Compound

PDB ID

Not Available

ChEBI ID

15978

References

General References

Not Available

Only showing the first 10 proteins. There are 21 proteins in total.

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Enzymes

Enzyme Details

1. Glycerol-3-phosphate dehydrogenase, mitochondrial

General function:: Involved in calcium ion binding
Specific function:: Not Available
Gene Name:: GPD2
Uniprot ID:: P43304
Molecular weight:: 80851.99

Enzyme Details

2. Glycerol kinase 2

General function:: Involved in phosphotransferase activity, alcohol group as acceptor
Specific function:: Key enzyme in the regulation of glycerol uptake and metabolism (By similarity).
Gene Name:: GK2
Uniprot ID:: Q14410
Molecular weight:: 60593.32

Enzyme Details

3. Glycerol kinase

General function:: Involved in phosphotransferase activity, alcohol group as acceptor
Specific function:: Key enzyme in the regulation of glycerol uptake and metabolism.
Gene Name:: GK
Uniprot ID:: P32189
Molecular weight:: 57488.675

Enzyme Details

4. Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic

General function:: Involved in oxidoreductase activity
Specific function:: Not Available
Gene Name:: GPD1
Uniprot ID:: P21695
Molecular weight:: 37567.4

Enzyme Details

5. Glycerol-3-phosphate acyltransferase 1, mitochondrial

General function:: Involved in acyltransferase activity
Specific function:: Esterifies acyl-group from acyl-ACP to the sn-1 position of glycerol-3-phosphate, an essential step in glycerolipid biosynthesis.
Gene Name:: GPAM
Uniprot ID:: Q9HCL2
Molecular weight:: 93793.895

Enzyme Details

6. Putative glycerol kinase 3

General function:: Involved in phosphotransferase activity, alcohol group as acceptor
Specific function:: Key enzyme in the regulation of glycerol uptake and metabolism.
Gene Name:: GK3P
Uniprot ID:: Q14409
Molecular weight:: Not Available

Enzyme Details

7. Glycerol-3-phosphate acyltransferase 4

General function:: Involved in acyltransferase activity
Specific function:: Esterifies acyl-group from acyl-ACP to the sn-1 position of glycerol-3-phosphate, an essential step in glycerolipid biosynthesis. Active against both saturated and unsaturated long-chain fatty acyl-CoAs.
Gene Name:: AGPAT6
Uniprot ID:: Q86UL3
Molecular weight:: 52070.605

Enzyme Details

8. CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial

General function:: Involved in phosphotransferase activity, for other substituted phosphate groups
Specific function:: Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin (By similarity).
Gene Name:: PGS1
Uniprot ID:: Q32NB8
Molecular weight:: 62729.745

Enzyme Details

9. Glycerol-3-phosphate dehydrogenase 1-like protein

General function:: Involved in oxidoreductase activity
Specific function:: Plays a role in regulating cardiac sodium current; decreased enzymatic activity with resulting increased levels of glycerol 3-phosphate activating the DPD1L-dependent SCN5A phosphorylation pathway, may ultimately lead to decreased sodium current; cardiac sodium current may also be reduced due to alterations of NAD(H) balance induced by DPD1L.
Gene Name:: GPD1L
Uniprot ID:: Q8N335
Molecular weight:: 38418.44

Enzyme Details

10. Glycerol-3-phosphate acyltransferase 3

General function:: Involved in acyltransferase activity
Specific function:: Esterifies acyl-group from acyl-ACP to the sn-1 position of glycerol-3-phosphate, an essential step in glycerolipid biosynthesis. Overexpression activates the mTOR pathway.
Gene Name:: AGPAT9
Uniprot ID:: Q53EU6
Molecular weight:: 48704.805

Transporters

Enzyme Details

1. Glycerol-3-phosphate dehydrogenase 1-like protein

General function:: Involved in oxidoreductase activity
Specific function:: Plays a role in regulating cardiac sodium current; decreased enzymatic activity with resulting increased levels of glycerol 3-phosphate activating the DPD1L-dependent SCN5A phosphorylation pathway, may ultimately lead to decreased sodium current; cardiac sodium current may also be reduced due to alterations of NAD(H) balance induced by DPD1L.
Gene Name:: GPD1L
Uniprot ID:: Q8N335
Molecular weight:: 38418.44

Only showing the first 10 proteins. There are 21 proteins in total.

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Showing Compound Card for Glycerol 3-phosphate (CDB004806)

Structure for CDB004806 (Glycerol 3-phosphate)

Enzymes

Transporters