Cannabis Compound Database: Showing Compound Card for ethanolamine (CDB000232)

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Identification Taxonomy Ontology Physical properties Spectra Protein target Pathways Concentrations Links References enzymes (16) Show 23 proteins XML

Record Information

Version

1.0

Created at

2020-03-19 00:25:51 UTC

Updated at

2020-12-07 19:07:16 UTC

CannabisDB ID

CDB000232

Secondary Accession Numbers

Not Available

Cannabis Compound Identification

Common Name

ethanolamine

Description

Ethanolamine, also known as aminoethanol or glycinol, belongs to the class of organic compounds known as 1,2-aminoalcohols. These are organic compounds containing an alkyl chain with an amine group bound to the C1 atom and an alcohol group bound to the C2 atom. Ethanolamine is a weak basic compound (based on its pKa). Ethanolamine exists in all living species, ranging from bacteria to humans and it is also present in Cannabis sativa plants (PMID: 6991645 ). Ethanolamine can be converted into O-phosphoethanolamine through the action of the enzyme choline/ethanolamine kinase. In humans, ethanolamine is involved in phosphatidylcholine biosynthesis. Ethanolamine has been detected in several different foods, such as millets, chickpea, abalones, common salsifies, and oriental wheats. Like other amines, monoethanolamine is a weak base and this property is exploited in its use in gas scrubbing. The ratio of the products can be controlled by the stoichiometry of the reactants. Reacting ethanolamine with ammonia gives ethylenediamine, a precursor of the commonly used chelating agent EDTA. It is also used in messenger molecules such as palmitoylethanolamide, which has an effect on CB1 receptors.

Structure

MOL SDF PDB SMILES InChI

Synonyms

Value	Source
1-Amino-2-hydroxyethane	ChEBI
2-Amino-1-ethanol	ChEBI
2-Amino-ethanol	ChEBI
2-Aminoethan-1-ol	ChEBI
2-Aminoethyl alcohol	ChEBI
2-Hydroxyethylamine	ChEBI
Aethanolamin	ChEBI
Aminoethanol	ChEBI
beta-Aminoethanol	ChEBI
beta-Aminoethyl alcohol	ChEBI
beta-Ethanolamine	ChEBI
beta-Hydroxyethylamine	ChEBI
Colamine	ChEBI
ETA	ChEBI
Glycinol	ChEBI
Hea	ChEBI
MEA	ChEBI
MONOETHANOLAMINE	ChEBI
b-Aminoethanol	Generator
Β-aminoethanol	Generator
b-Aminoethyl alcohol	Generator
Β-aminoethyl alcohol	Generator
b-Ethanolamine	Generator
Β-ethanolamine	Generator
b-Hydroxyethylamine	Generator
Β-hydroxyethylamine	Generator
2-Aminoethanol	HMDB
2-Ethanolamine	HMDB
2-Hydroxyethanamine	HMDB
Envision conditioner PDD 9020	HMDB
Ethylolamine	HMDB
H-Glycinol	HMDB
Monoaethanolamin	HMDB
Olamine	HMDB
2 Aminoethanol	HMDB
Ethanolamine	PhytoBank
Kolamin	PhytoBank

Chemical Formula

C₂H₇NO

Average Molecular Weight

61.08

Monoisotopic Molecular Weight

61.0528

IUPAC Name

2-aminoethan-1-ol

Traditional Name

ethanolamine

CAS Registry Number

9007-33-4

SMILES

NCCO

InChI Identifier

InChI=1S/C2H7NO/c3-1-2-4/h4H,1-3H2

InChI Key

HZAXFHJVJLSVMW-UHFFFAOYSA-N

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as 1,2-aminoalcohols. These are organic compounds containing an alkyl chain with an amine group bound to the C1 atom and an alcohol group bound to the C2 atom.

Kingdom

Organic compounds

Super Class

Organic nitrogen compounds

Class

Organonitrogen compounds

Sub Class

Amines

Direct Parent

1,2-aminoalcohols

Alternative Parents

Substituents

1,2-aminoalcohol
Organic oxygen compound
Organopnictogen compound
Hydrocarbon derivative
Primary amine
Primary alcohol
Organooxygen compound
Primary aliphatic amine
Alcohol
Aliphatic acyclic compound

Molecular Framework

Aliphatic acyclic compounds

External Descriptors

primary alcohol (CHEBI:16000 )
primary amine (CHEBI:16000 )
ethanolamines (CHEBI:16000 )
Biogenic amines (C00189 )
a small molecule (ETHANOL-AMINE )

Ontology

Disposition

Route of exposure:

Enteral:

Ingestion

Source:

Synthetic:

Personal care product

Biological:

Animal

Plant:

Biological location:

Organ and components:

Cell and elements:

Cell:

Nerve cell

Tissue and substructures:

Biofluid and excreta:

Subcellular:

Role

Industrial application:

Pharmaceutical industry:

Pharmaceutical

Physical Properties

State

Solid

Experimental Properties

Property	Value	Reference
Melting Point	10.5 °C	Not Available
Boiling Point	170 °C	Wikipedia
Water Solubility	1000 mg/mL	Not Available
logP	-1.31	HANSCH,C ET AL. (1995)

Predicted Properties

Property	Value	Source
logP	-1.5	ALOGPS
logP	-1.3	ChemAxon
logS	1.14	ALOGPS
pKa (Strongest Acidic)	15.61	ChemAxon
pKa (Strongest Basic)	9.55	ChemAxon
Physiological Charge	1	ChemAxon
Hydrogen Acceptor Count	2	ChemAxon
Hydrogen Donor Count	2	ChemAxon
Polar Surface Area	46.25 Å²	ChemAxon
Rotatable Bond Count	1	ChemAxon
Refractivity	16.21 m³·mol⁻¹	ChemAxon
Polarizability	6.63 Å³	ChemAxon
Number of Rings	0	ChemAxon
Bioavailability	Yes	ChemAxon
Rule of Five	Yes	ChemAxon
Ghose Filter	No	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	No	ChemAxon

Spectra

EI-MS/GC-MS

Type	Description	Splash Key	View
EI-MS	Mass Spectrum (Electron Ionization)	splash10-001i-9000000000-b8e7ed9f5ad724511431	2014-09-20	View Spectrum
GC-MS	ethanolamine, 3 TMS, GC-MS Spectrum	splash10-00di-1900000000-b64e859a0bfc46cdfcbf	Spectrum
GC-MS	ethanolamine, 3 TMS, GC-MS Spectrum	splash10-00di-1900000000-384c99d021f0303a9d78	Spectrum
GC-MS	ethanolamine, non-derivatized, GC-MS Spectrum	splash10-00di-1900000000-d731dd07c2dfa0287f5f	Spectrum
GC-MS	ethanolamine, 3 TMS, GC-MS Spectrum	splash10-00di-8900000000-ec4268b6041043d15437	Spectrum
GC-MS	ethanolamine, 3 TMS, GC-MS Spectrum	splash10-00di-2900000000-02697b8ce238020537aa	Spectrum
GC-MS	ethanolamine, non-derivatized, GC-MS Spectrum	splash10-001i-9000000000-7160c3fea0c0159e447a	Spectrum
GC-MS	ethanolamine, non-derivatized, GC-MS Spectrum	splash10-001i-9000000000-2af16a98e43fadfa86a3	Spectrum
GC-MS	ethanolamine, non-derivatized, GC-MS Spectrum	splash10-00di-1900000000-b64e859a0bfc46cdfcbf	Spectrum
GC-MS	ethanolamine, non-derivatized, GC-MS Spectrum	splash10-00di-1900000000-384c99d021f0303a9d78	Spectrum
GC-MS	ethanolamine, non-derivatized, GC-MS Spectrum	splash10-00di-1900000000-d731dd07c2dfa0287f5f	Spectrum
GC-MS	ethanolamine, non-derivatized, GC-MS Spectrum	splash10-00di-8900000000-ec4268b6041043d15437	Spectrum
GC-MS	ethanolamine, non-derivatized, GC-MS Spectrum	splash10-00di-2900000000-02697b8ce238020537aa	Spectrum
GC-MS	ethanolamine, non-derivatized, GC-MS Spectrum	splash10-0fki-2900000000-37831b0ceb554ca4edd2	Spectrum
Predicted GC-MS	ethanolamine, non-derivatized, Predicted GC-MS Spectrum - 70eV, Positive	splash10-001i-9000000000-e06e8502ffb0d4113432	Spectrum
Predicted GC-MS	ethanolamine, 1 TMS, Predicted GC-MS Spectrum - 70eV, Positive	splash10-001i-9100000000-e2cbdef448451ceae424	Spectrum
Predicted GC-MS	ethanolamine, non-derivatized, Predicted GC-MS Spectrum - 70eV, Positive	Not Available	Spectrum
Predicted GC-MS	ethanolamine, TMS_1_2, Predicted GC-MS Spectrum - 70eV, Positive	Not Available	Spectrum
Predicted GC-MS	ethanolamine, TBDMS_1_1, Predicted GC-MS Spectrum - 70eV, Positive	Not Available	Spectrum
Predicted GC-MS	ethanolamine, TBDMS_1_2, Predicted GC-MS Spectrum - 70eV, Positive	Not Available	Spectrum

MS/MS

Type	Description	Splash Key	View
MS/MS	LC-MS/MS Spectrum - Quattro_QQQ 10V, Positive (Annotated)	splash10-03dl-9000000000-17dee0c07bf5cddb79ce	2012-07-24	View Spectrum
MS/MS	LC-MS/MS Spectrum - Quattro_QQQ 25V, Positive (Annotated)	splash10-03di-9000000000-04f4c1792f8ab4f4646f	2012-07-24	View Spectrum
MS/MS	LC-MS/MS Spectrum - Quattro_QQQ 40V, Positive (Annotated)	splash10-03di-9000000000-761836be8f1018081210	2012-07-24	View Spectrum
MS/MS	LC-MS/MS Spectrum - EI-B (HITACHI RMU-7M) , Positive	splash10-001i-9000000000-7160c3fea0c0159e447a	2012-08-31	View Spectrum
MS/MS	LC-MS/MS Spectrum - EI-B (HITACHI M-68) , Positive	splash10-001i-9000000000-2af16a98e43fadfa86a3	2012-08-31	View Spectrum
MS/MS	LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 10V, Positive	splash10-03di-9000000000-ae5b80bd3c5c11914ea6	2012-08-31	View Spectrum
MS/MS	LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 20V, Positive	splash10-0006-9000000000-6abb3d0944e188778c65	2012-08-31	View Spectrum
MS/MS	LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 30V, Positive	splash10-0007-9000000000-e477e52f411d933a30b7	2012-08-31	View Spectrum
MS/MS	LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 40V, Positive	splash10-0006-9000000000-d7979261a3716365d5ae	2012-08-31	View Spectrum
MS/MS	LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 50V, Positive	splash10-03di-9000000000-5c0261b2dcc6ae1291a1	2012-08-31	View Spectrum
MS/MS	LC-MS/MS Spectrum - LC-ESI-QQ , positive	splash10-03di-9000000000-ae5b80bd3c5c11914ea6	2017-09-14	View Spectrum
MS/MS	LC-MS/MS Spectrum - LC-ESI-QQ , positive	splash10-0006-9000000000-6abb3d0944e188778c65	2017-09-14	View Spectrum
MS/MS	LC-MS/MS Spectrum - LC-ESI-QQ , positive	splash10-0007-9000000000-e477e52f411d933a30b7	2017-09-14	View Spectrum
MS/MS	LC-MS/MS Spectrum - LC-ESI-QQ , positive	splash10-0006-9000000000-d7979261a3716365d5ae	2017-09-14	View Spectrum
MS/MS	LC-MS/MS Spectrum - LC-ESI-QQ , positive	splash10-03di-9000000000-5c0261b2dcc6ae1291a1	2017-09-14	View Spectrum
MS/MS	LC-MS/MS Spectrum - 0V, Positive	splash10-03di-9000000000-f09b61222ca342d2835c	2021-09-20	View Spectrum
MS/MS	LC-MS/MS Spectrum - 10V, Positive	splash10-03di-9000000000-3f9346b7fb6fdd5c5ce8	2021-09-20	View Spectrum
MS/MS	LC-MS/MS Spectrum - 30V, Positive	splash10-03di-9000000000-f73d8d00f0f234521971	2021-09-20	View Spectrum
MS/MS	LC-MS/MS Spectrum - 10V, Positive	splash10-03di-9000000000-eec6f92ad146ef43c111	2021-09-20	View Spectrum
Predicted MS/MS	Predicted LC-MS/MS Spectrum - 10V, Positive	splash10-03di-9000000000-9e6d219a7fbd8624cd6b	2015-05-26	View Spectrum
Predicted MS/MS	Predicted LC-MS/MS Spectrum - 20V, Positive	splash10-01ox-9000000000-fb9020ee9b301ec7766f	2015-05-26	View Spectrum
Predicted MS/MS	Predicted LC-MS/MS Spectrum - 40V, Positive	splash10-0006-9000000000-a4ae359cfcc0245b4d19	2015-05-26	View Spectrum
Predicted MS/MS	Predicted LC-MS/MS Spectrum - 10V, Negative	splash10-03di-9000000000-b6ed81bc049b8d3042f6	2015-05-27	View Spectrum
Predicted MS/MS	Predicted LC-MS/MS Spectrum - 20V, Negative	splash10-03dl-9000000000-78c77096ed599182b5bb	2015-05-27	View Spectrum
Predicted MS/MS	Predicted LC-MS/MS Spectrum - 40V, Negative	splash10-0006-9000000000-f199cbf8312e0b466f1b	2015-05-27	View Spectrum

NMR

Type	Description	View
1D NMR	¹H NMR Spectrum (1D, 600 MHz, H₂O, experimental)	Spectrum
1D NMR	¹³C NMR Spectrum (1D, 125 MHz, H₂O, experimental)	Spectrum
1D NMR	¹H NMR Spectrum (1D, 90 MHz, CDCl₃, experimental)	Spectrum
1D NMR	¹³C NMR Spectrum (1D, 15.09 MHz, CDCl₃, experimental)	Spectrum
1D NMR	¹H NMR Spectrum (1D, D₂O, experimental)	Spectrum
1D NMR	¹H NMR Spectrum (1D, D₂O, experimental)	Spectrum
1D NMR	¹³C NMR Spectrum (1D, D₂O, experimental)	Spectrum
1D NMR	¹³C NMR Spectrum (1D, 100 MHz, D₂O, predicted)	Spectrum
1D NMR	¹H NMR Spectrum (1D, 100 MHz, D₂O, predicted)	Spectrum
1D NMR	¹³C NMR Spectrum (1D, 200 MHz, D₂O, predicted)	Spectrum
1D NMR	¹H NMR Spectrum (1D, 200 MHz, D₂O, predicted)	Spectrum
1D NMR	¹³C NMR Spectrum (1D, 300 MHz, D₂O, predicted)	Spectrum
1D NMR	¹H NMR Spectrum (1D, 300 MHz, D₂O, predicted)	Spectrum
1D NMR	¹³C NMR Spectrum (1D, 400 MHz, D₂O, predicted)	Spectrum
1D NMR	¹H NMR Spectrum (1D, 400 MHz, D₂O, predicted)	Spectrum
1D NMR	¹³C NMR Spectrum (1D, 500 MHz, D₂O, predicted)	Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, D₂O, predicted)	Spectrum
1D NMR	¹³C NMR Spectrum (1D, 600 MHz, D₂O, predicted)	Spectrum
1D NMR	¹H NMR Spectrum (1D, 600 MHz, D₂O, predicted)	Spectrum
1D NMR	¹³C NMR Spectrum (1D, 700 MHz, D₂O, predicted)	Spectrum
1D NMR	¹H NMR Spectrum (1D, 700 MHz, D₂O, predicted)	Spectrum
1D NMR	¹³C NMR Spectrum (1D, 800 MHz, D₂O, predicted)	Spectrum
1D NMR	¹H NMR Spectrum (1D, 800 MHz, D₂O, predicted)	Spectrum
1D NMR	¹³C NMR Spectrum (1D, 900 MHz, D₂O, predicted)	Spectrum
1D NMR	¹H NMR Spectrum (1D, 900 MHz, D₂O, predicted)	Spectrum
2D NMR	[¹H, ¹H]-TOCSY. Unexported temporarily by An Chi on Oct 15, 2021 until json or nmrML file is generated. 2D NMR Spectrum (experimental)	Spectrum
2D NMR	[¹H, ¹³C]-HSQC NMR Spectrum (2D, 600 MHz, H₂O, experimental)	Spectrum

Pathways

Name	SMPDB/Pathwhiz	KEGG
Phospholipid Biosynthesis
Phosphatidylcholine Biosynthesis		Not Available
Phosphatidylcholine Biosynthesis PC(14:0/14:0)		Not Available
Phosphatidylcholine Biosynthesis PC(14:0/14:1(9Z))		Not Available
Phosphatidylcholine Biosynthesis PC(14:0/15:0)		Not Available

Protein Targets

Enzymes

Protein Name	Gene Name	Locus	Uniprot ID	Details
Phospholipase D2	PLD2	17p13.1	O14939	details
Phospholipase D1	PLD1	3q26	Q13393	details
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2	ENPP2	8q24.1	Q13822	details
Choline/ethanolamine kinase	CHKB	22q13.33	Q9Y259	details
Choline kinase alpha	CHKA	11q13.2	P35790	details
Ethanolamine kinase 1	ETNK1	12p12.1	Q9HBU6	details
Phosphatidylserine synthase 1	PTDSS1	8q22	P48651	details
Fatty-acid amide hydrolase 1	FAAH	1p35-p34	O00519	details
Phosphatidylserine synthase 2	PTDSS2	11p15.5	Q9BVG9	details
Phosphoethanolamine/phosphocholine phosphatase	PHOSPHO1	17q21.32	Q8TCT1	details
Ethanolamine kinase 2	ETNK2	1q32.1	Q9NVF9	details
Phospholipase D3	PLD3	19q13.2	Q8IV08	details
Phospholipase D4	PLD4	14q32.33	Q96BZ4	details
Glycerophosphodiester phosphodiesterase 1	GDE1	16p12-p11.2	Q9NZC3	details
Fatty-acid amide hydrolase 2	FAAH2	Xp11.21	Q6GMR7	details
Phospholipase D1 variant			Q59EA4	details

Transporters

Not Available

Metal Bindings

Protein Name	Gene Name	Locus	Uniprot ID	Details
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2	ENPP2	8q24.1	Q13822	details
Annexin A3	ANXA3	4q21.21	P12429	details
Phosphoethanolamine/phosphocholine phosphatase	PHOSPHO1	17q21.32	Q8TCT1	details
Glycerophosphodiester phosphodiesterase 1	GDE1	16p12-p11.2	Q9NZC3	details

Receptors

Protein Name	Gene Name	Locus	Uniprot ID	Details
Phospholipase D2	PLD2	17p13.1	O14939	details
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2	ENPP2	8q24.1	Q13822	details

Transcriptional Factors

Protein Name	Gene Name	Locus	Uniprot ID	Details
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2	ENPP2	8q24.1	Q13822	details

Concentrations Data

Not Available

External Links

HMDB ID

HMDB0000149

DrugBank ID

DB03994

Phenol Explorer Compound ID

Not Available

FoodDB ID

KNApSAcK ID

Chemspider ID

KEGG Compound ID

BioCyc ID

BiGG ID

Wikipedia Link

METLIN ID

PubChem Compound

PDB ID

Not Available

ChEBI ID

16000

References

General References

Turner CE, Elsohly MA, Boeren EG: Constituents of Cannabis sativa L. XVII. A review of the natural constituents. J Nat Prod. 1980 Mar-Apr;43(2):169-234. doi: 10.1021/np50008a001. [PubMed:6991645 ]

Only showing the first 10 proteins. There are 23 proteins in total.

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Enzymes

Enzyme Details

1. Phospholipase D2

General function:: Involved in protein binding
Specific function:: May have a role in signal-induced cytoskeletal regulation and/or endocytosis (By similarity).
Gene Name:: PLD2
Uniprot ID:: O14939
Molecular weight:: 104656.485

Enzyme Details

2. Phospholipase D1

General function:: Involved in protein binding
Specific function:: Implicated as a critical step in numerous cellular pathways, including signal transduction, membrane trafficking, and the regulation of mitosis. May be involved in the regulation of perinuclear intravesicular membrane traffic (By similarity).
Gene Name:: PLD1
Uniprot ID:: Q13393
Molecular weight:: 124183.135

Enzyme Details

3. Ectonucleotide pyrophosphatase/phosphodiesterase family member 2

General function:: Involved in catalytic activity
Specific function:: Hydrolyzes lysophospholipids to produce lysophosphatidic acid (LPA) in extracellular fluids. Major substrate is lysophosphatidylcholine. Also can act on sphingosylphosphphorylcholine producing sphingosine-1-phosphate, a modulator of cell motility. Can hydrolyze, in vitro, bis-pNPP, to some extent pNP-TMP, and barely ATP. Involved in several motility-related processes such as angiogenesis and neurite outgrowth. Acts as an angiogenic factor by stimulating migration of smooth muscle cells and microtubule formation. Stimulates migration of melanoma cells, probably via a pertussis toxin-sensitive G protein. May have a role in induction of parturition. Possible involvement in cell proliferation and adipose tissue development. Tumor cell motility-stimulating factor.
Gene Name:: ENPP2
Uniprot ID:: Q13822
Molecular weight:: 98992.78

Enzyme Details

4. Choline/ethanolamine kinase

General function:: Cell wall/membrane/envelope biogenesis
Specific function:: Has a key role in phospholipid biosynthesis. Catalyzes the first step in phosphatidylethanolamine biosynthesis. Phosphorylates ethanolamine, and can also act on choline (in vitro). Has higher activity with ethanolamine. May not significantly contribute to in vivo phosphatidylcholine biosynthesis.
Gene Name:: CHKB
Uniprot ID:: Q9Y259
Molecular weight:: 45270.99

Enzyme Details

5. Choline kinase alpha

General function:: Cell wall/membrane/envelope biogenesis
Specific function:: Has a key role in phospholipid biosynthesis and may contribute to tumor cell growth. Catalyzes the first step in phosphatidylcholine biosynthesis. Contributes to phosphatidylethanolamine biosynthesis. Phosphorylates choline and ethanolamine. Has higher activity with choline.
Gene Name:: CHKA
Uniprot ID:: P35790
Molecular weight:: 52248.53

Enzyme Details

6. Ethanolamine kinase 1

General function:: Cell wall/membrane/envelope biogenesis
Specific function:: Highly specific for ethanolamine phosphorylation. May be a rate-controlling step in phosphatidylethanolamine biosynthesis.
Gene Name:: ETNK1
Uniprot ID:: Q9HBU6
Molecular weight:: 27994.955

Enzyme Details

7. Phosphatidylserine synthase 1

General function:: Involved in phosphatidylserine biosynthetic process
Specific function:: Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) or phosphatidylcholine (PC) is replaced by L-serine. In membranes, PTDSS1 catalyzes mainly the conversion of phosphatidylcholine. Also converts, in vitro and to a lesser extent, phosphatidylethanolamine.
Gene Name:: PTDSS1
Uniprot ID:: P48651
Molecular weight:: 55527.18

Enzyme Details

8. Fatty-acid amide hydrolase 1

General function:: Involved in carbon-nitrogen ligase activity, with glutamine as amido-N-donor
Specific function:: Degrades bioactive fatty acid amides like oleamide, the endogenous cannabinoid, anandamide and myristic amide to their corresponding acids, thereby serving to terminate the signaling functions of these molecules. Hydrolyzes polyunsaturated substrate anandamide preferentially as compared to monounsaturated substrates.
Gene Name:: FAAH
Uniprot ID:: O00519
Molecular weight:: 63065.28

Enzyme Details

9. Phosphatidylserine synthase 2

General function:: Involved in phosphatidylserine biosynthetic process
Specific function:: Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) or phosphatidylcholine (PC) is replaced by L-serine. PTDSS2 is specific for phosphatatidylethanolamine and does not act on phosphatidylcholine.
Gene Name:: PTDSS2
Uniprot ID:: Q9BVG9
Molecular weight:: 56252.55

Enzyme Details

10. Phosphoethanolamine/phosphocholine phosphatase

General function:: Involved in phosphatase activity
Specific function:: Phosphatase that has a high activity toward phosphoethanolamine (PEA) and phosphocholine (PCho). Involved in the generation of inorganic phosphate for bone mineralization.
Gene Name:: PHOSPHO1
Uniprot ID:: Q8TCT1
Molecular weight:: 32350.505

Only showing the first 10 proteins. There are 23 proteins in total.

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Showing Compound Card for ethanolamine (CDB000232)

Structure for CDB000232 (ethanolamine)

Enzymes