Cannabis Compound Database: Showing Compound Card for Nicotinic acid (CDB004918)

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Identification Taxonomy Ontology Physical properties Spectra Protein target Pathways Concentrations Links References enzymes (6)transporters (3) Show 12 proteins XML

Record Information

Version

1.0

Created at

2020-04-17 18:50:23 UTC

Updated at

2020-12-07 19:11:16 UTC

CannabisDB ID

CDB004918

Secondary Accession Numbers

Not Available

Cannabis Compound Identification

Common Name

Nicotinic acid

Description

Nicotinic acid, also known as niacin or 3-carboxypyridine, belongs to the class of organic compounds known as pyridinecarboxylic acids. Pyridinecarboxylic acids are compounds containing a pyridine ring bearing a carboxylic acid group. A pyridinemonocarboxylic acid that is pyridine in which the hydrogen at position 3 is replaced by a carboxy group. Nicotinic acid is a strong basic compound (based on its pKa). Nicotinic acid exists in all living species, ranging from bacteria to humans. nicotinic acid and ribose 1-phosphate can be biosynthesized from nicotinate D-ribonucleoside through its interaction with the enzyme purine nucleoside phosphorylase. In humans, nicotinic acid is involved in nicotinate and nicotinamide metabolism. Outside of the human body, Nicotinic acid is found, on average, in the highest concentration within a few different foods, such as beers, leavening agents, and yellowfin tuna and in a lower concentration in greater sturgeons, groundcherries, and muskmelons. Nicotinic acid has also been detected, but not quantified in, several different foods, such as chinese bayberries, pineappple sages, green vegetables, brassicas, and cupuaçus. This could make nicotinic acid a potential biomarker for the consumption of these foods. Nicotinic acid is a potentially toxic compound. Nicotinic acid is expected to be in Cannabis as all living plants are known to produce and metabolize it.

Structure

MOL SDF PDB SMILES InChI

Synonyms

Value	Source
3-Carboxypyridine	ChEBI
3-Pyridinecarboxylic acid	ChEBI
3-Pyridylcarboxylic acid	ChEBI
Acide nicotinique	ChEBI
Acido nicotinico	ChEBI
Acidum nicotinicum	ChEBI
Anti-pellagra vitamin	ChEBI
beta-Pyridinecarboxylic acid	ChEBI
m-Pyridinecarboxylic acid	ChEBI
Niacin	ChEBI
Nikotinsaeure	ChEBI
P.P. factor	ChEBI
Pellagra preventive factor	ChEBI
PP Factor	ChEBI
Pyridine-beta-carboxylic acid	ChEBI
Vitamin b3	ChEBI
Niacor	Kegg
Niaspan	Kegg
3-Pyridinecarboxylate	Generator
3-Pyridylcarboxylate	Generator
b-Pyridinecarboxylate	Generator
b-Pyridinecarboxylic acid	Generator
beta-Pyridinecarboxylate	Generator
Β-pyridinecarboxylate	Generator
Β-pyridinecarboxylic acid	Generator
m-Pyridinecarboxylate	Generator
Pyridine-b-carboxylate	Generator
Pyridine-b-carboxylic acid	Generator
Pyridine-beta-carboxylate	Generator
Pyridine-β-carboxylate	Generator
Pyridine-β-carboxylic acid	Generator
Nicotinate	Generator
3-Carboxylpyridine	HMDB
Akotin	HMDB
Apelagrin	HMDB
Daskil	HMDB
Efacin	HMDB
Enduracin	HMDB
Linic	HMDB
Niac	HMDB
Niacine	HMDB
Nicacid	HMDB
Nicamin	HMDB
Nicangin	HMDB
Nico-span	HMDB
Nicobid	HMDB
Nicocap	HMDB
Nicodelmine	HMDB
Nicolar	HMDB
Niconacid	HMDB
Nicosan 3	HMDB
Nicotinipca	HMDB
Nicyl	HMDB
Nyclin	HMDB
Pellagrin	HMDB
Pelonin	HMDB
Slo-niacin	HMDB
Wampocap	HMDB
Aluminum salt, niacin	HMDB
Induracin	HMDB
Niacin cobalt (2+) salt	HMDB
Niacin iron (2+) salt	HMDB
Niacin lithium salt	HMDB
Niacin magnesium salt	HMDB
Niacin sodium salt	HMDB
Nico-400	HMDB
Potassium salt, niacin	HMDB
Sodium salt, niacin	HMDB
Tosylate, niacin	HMDB
Nicotinate, lithium	HMDB
Hydrochloride, niacin	HMDB
Niacin aluminum salt	HMDB
Niacin calcium salt	HMDB
Niacin copper (2+) salt	HMDB
Niacin hydrochloride	HMDB
Niacin lithium salt, hemihydrate	HMDB
Nico400	HMDB
Tartrate, niacin	HMDB
3 Pyridinecarboxylic acid	HMDB
Lithium nicotinate	HMDB
Niacin ammonium salt	HMDB
Niacin manganese (2+) salt	HMDB
Niacin potassium salt	HMDB
Niacin tartrate	HMDB
Niacin tosylate	HMDB
Niacin zinc salt	HMDB
Nico 400	HMDB

Chemical Formula

C₆H₅NO₂

Average Molecular Weight

123.11

Monoisotopic Molecular Weight

123.032

IUPAC Name

pyridine-3-carboxylic acid

Traditional Name

niacin

CAS Registry Number

59-67-6

SMILES

OC(=O)C1=CN=CC=C1

InChI Identifier

InChI=1S/C6H5NO2/c8-6(9)5-2-1-3-7-4-5/h1-4H,(H,8,9)

InChI Key

PVNIIMVLHYAWGP-UHFFFAOYSA-N

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as pyridinecarboxylic acids. Pyridinecarboxylic acids are compounds containing a pyridine ring bearing a carboxylic acid group.

Kingdom

Organic compounds

Super Class

Organoheterocyclic compounds

Class

Pyridines and derivatives

Sub Class

Pyridinecarboxylic acids and derivatives

Direct Parent

Pyridinecarboxylic acids

Alternative Parents

Substituents

Pyridine carboxylic acid
Heteroaromatic compound
Azacycle
Monocarboxylic acid or derivatives
Carboxylic acid
Carboxylic acid derivative
Organic nitrogen compound
Organic oxygen compound
Organopnictogen compound
Organic oxide
Hydrocarbon derivative
Organooxygen compound
Organonitrogen compound
Aromatic heteromonocyclic compound

Molecular Framework

Aromatic heteromonocyclic compounds

External Descriptors

pyridine alkaloid (CHEBI:15940 )
pyridinemonocarboxylic acid (CHEBI:15940 )
Water-soluble vitamins (C00253 )
Pyridine alkaloids (C00253 )

Ontology

Metabolism and nutrition disorders:

Hyperglycemia

Eye disorders:

Blurred vision

Disposition

Route of exposure:

Enteral:

Ingestion

Parenteral:

Intramuscular

Source:

Synthetic:

Personal care product

Biological:

Animal

Plant:

Biological location:

Role

Industrial application:

Pharmaceutical industry:

Biological role:

Physical Properties

State

Solid

Experimental Properties

Property	Value	Reference
Melting Point	236.6 °C	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	18 mg/mL	Not Available
logP	0.36	SANGSTER (1993)

Predicted Properties

Property	Value	Source
logP	0.29	ALOGPS
logP	-0.17	ChemAxon
logS	-0.17	ALOGPS
pKa (Strongest Acidic)	2.79	ChemAxon
pKa (Strongest Basic)	4.19	ChemAxon
Physiological Charge	-1	ChemAxon
Hydrogen Acceptor Count	3	ChemAxon
Hydrogen Donor Count	1	ChemAxon
Polar Surface Area	50.19 Å²	ChemAxon
Rotatable Bond Count	1	ChemAxon
Refractivity	31.16 m³·mol⁻¹	ChemAxon
Polarizability	11.3 Å³	ChemAxon
Number of Rings	1	ChemAxon
Bioavailability	Yes	ChemAxon
Rule of Five	Yes	ChemAxon
Ghose Filter	No	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	No	ChemAxon

Spectra

EI-MS/GC-MS

Type	Description	Splash Key	View
EI-MS	Mass Spectrum (Electron Ionization)	splash10-0kor-8900000000-7d3f033a49f5fad75f33	2014-09-20	View Spectrum
GC-MS	Nicotinic acid, 1 TMS, GC-MS Spectrum	splash10-053i-0900000000-5daf0093df6c21c7279f	Spectrum
GC-MS	Nicotinic acid, 1 TMS, GC-MS Spectrum	splash10-053i-0900000000-f38b6609b45de8c74565	Spectrum
GC-MS	Nicotinic acid, non-derivatized, GC-MS Spectrum	splash10-0540-0900000000-4f55c81a6cd42f1b961d	Spectrum
GC-MS	Nicotinic acid, 1 TMS, GC-MS Spectrum	splash10-057r-5900000000-00bf3662b5b9db533c0a	Spectrum
GC-MS	Nicotinic acid, 1 TMS, GC-MS Spectrum	splash10-0569-2900000000-7820ea736b03b71d2cb8	Spectrum
GC-MS	Nicotinic acid, non-derivatized, GC-MS Spectrum	splash10-0kmi-7900000000-9e4efda763cce5ddfe57	Spectrum
GC-MS	Nicotinic acid, non-derivatized, GC-MS Spectrum	splash10-053i-0900000000-5daf0093df6c21c7279f	Spectrum
GC-MS	Nicotinic acid, non-derivatized, GC-MS Spectrum	splash10-053i-0900000000-f38b6609b45de8c74565	Spectrum
GC-MS	Nicotinic acid, non-derivatized, GC-MS Spectrum	splash10-0540-0900000000-4f55c81a6cd42f1b961d	Spectrum
GC-MS	Nicotinic acid, non-derivatized, GC-MS Spectrum	splash10-057r-5900000000-00bf3662b5b9db533c0a	Spectrum
GC-MS	Nicotinic acid, non-derivatized, GC-MS Spectrum	splash10-0569-2900000000-7820ea736b03b71d2cb8	Spectrum
GC-MS	Nicotinic acid, non-derivatized, GC-MS Spectrum	splash10-0540-0900000000-a701904fe6ded0abd98f	Spectrum
Predicted GC-MS	Nicotinic acid, non-derivatized, Predicted GC-MS Spectrum - 70eV, Positive	splash10-05i0-9700000000-d7620f1dc8f42d1498b9	Spectrum
Predicted GC-MS	Nicotinic acid, 1 TMS, Predicted GC-MS Spectrum - 70eV, Positive	splash10-05fr-9600000000-c3303cf4e83870b3e656	Spectrum
Predicted GC-MS	Nicotinic acid, non-derivatized, Predicted GC-MS Spectrum - 70eV, Positive	Not Available	Spectrum
Predicted GC-MS	Nicotinic acid, non-derivatized, Predicted GC-MS Spectrum - 70eV, Positive	Not Available	Spectrum

MS/MS

Type	Description	Splash Key	View
MS/MS	LC-MS/MS Spectrum - Quattro_QQQ 10V, Positive (Annotated)	splash10-00di-1900000000-27508608b33f1fb9f221	2012-07-24	View Spectrum
MS/MS	LC-MS/MS Spectrum - Quattro_QQQ 25V, Positive (Annotated)	splash10-003r-9100000000-a2037c9695659dceabd1	2012-07-24	View Spectrum
MS/MS	LC-MS/MS Spectrum - Quattro_QQQ 40V, Positive (Annotated)	splash10-0ufr-9100000000-4a2649a83ad2a40e5194	2012-07-24	View Spectrum
MS/MS	LC-MS/MS Spectrum - EI-B (HITACHI M-80) , Positive	splash10-0kmi-7900000000-1bc47d1b1850f54fb7c2	2012-08-31	View Spectrum
MS/MS	LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 10V, Negative	splash10-00di-1900000000-a352c5ce16d4b682b052	2012-08-31	View Spectrum
MS/MS	LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 20V, Negative	splash10-004i-9000000000-ab23ecb032e387b40bd9	2012-08-31	View Spectrum
MS/MS	LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 30V, Negative	splash10-004i-9000000000-02e37a1cfd3947037579	2012-08-31	View Spectrum
MS/MS	LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 40V, Negative	splash10-004i-9000000000-75d7e6658d2d6eca736e	2012-08-31	View Spectrum
MS/MS	LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 50V, Negative	splash10-0udi-9000000000-21a2d68d4f364c596f1d	2012-08-31	View Spectrum
MS/MS	LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 10V, Positive	splash10-0ab9-0900000000-a74db528f61c435876c8	2012-08-31	View Spectrum
MS/MS	LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 20V, Positive	splash10-00di-6900000000-773c08ab92ace4d48a9c	2012-08-31	View Spectrum
MS/MS	LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 30V, Positive	splash10-00aj-9100000000-07b12fbe942e6c7fb12d	2012-08-31	View Spectrum
MS/MS	LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 40V, Positive	splash10-005a-9000000000-66e0a5ba2ca8dbba1ed5	2012-08-31	View Spectrum
MS/MS	LC-MS/MS Spectrum - LC-ESI-QQ (API3000, Applied Biosystems) 50V, Positive	splash10-004i-9000000000-fbf8ba47b56d7cc7be81	2012-08-31	View Spectrum
MS/MS	LC-MS/MS Spectrum - LC-ESI-QTOF (UPLC Q-Tof Premier, Waters) , Positive	splash10-00di-0900000000-eaf82f6ab0befde118e9	2012-08-31	View Spectrum
MS/MS	LC-MS/MS Spectrum - LC-ESI-QTOF (UPLC Q-Tof Premier, Waters) 30V, Positive	splash10-00di-0900000000-eaf82f6ab0befde118e9	2012-08-31	View Spectrum
MS/MS	LC-MS/MS Spectrum - LC-ESI-QTOF (UPLC Q-Tof Premier, Waters) , Negative	splash10-004i-9300000000-b1a48f694fba565108a1	2012-08-31	View Spectrum
MS/MS	LC-MS/MS Spectrum - LC-ESI-QQ , negative	splash10-00di-1900000000-a352c5ce16d4b682b052	2017-09-14	View Spectrum
MS/MS	LC-MS/MS Spectrum - LC-ESI-QQ , negative	splash10-004i-9000000000-ab23ecb032e387b40bd9	2017-09-14	View Spectrum
Predicted MS/MS	Predicted LC-MS/MS Spectrum - 10V, Positive	splash10-00di-0900000000-25068c42378f72756922	2016-09-12	View Spectrum
Predicted MS/MS	Predicted LC-MS/MS Spectrum - 20V, Positive	splash10-00di-3900000000-6278a1e122005f48fcaf	2016-09-12	View Spectrum
Predicted MS/MS	Predicted LC-MS/MS Spectrum - 40V, Positive	splash10-0ue9-9000000000-e4e41ed9bef32955889e	2016-09-12	View Spectrum
Predicted MS/MS	Predicted LC-MS/MS Spectrum - 10V, Negative	splash10-00di-4900000000-85d44ecd8ad348eeacd1	2016-09-12	View Spectrum
Predicted MS/MS	Predicted LC-MS/MS Spectrum - 20V, Negative	splash10-004i-9300000000-4911305982583ae20895	2016-09-12	View Spectrum
Predicted MS/MS	Predicted LC-MS/MS Spectrum - 40V, Negative	splash10-004i-9000000000-4dea4a2d4a55907605ea	2016-09-12	View Spectrum

NMR

Type	Description	View
1D NMR	¹H NMR Spectrum (1D, 600 MHz, H₂O, experimental)	Spectrum
1D NMR	¹H NMR Spectrum (1D, 400 MHz, DMSO-d6, experimental)	Spectrum
1D NMR	¹³C NMR Spectrum (1D, 22.53 MHz, DMSO-d6, experimental)	Spectrum
1D NMR	¹H NMR Spectrum (1D, D₂O, experimental)	Spectrum
1D NMR	¹³C NMR Spectrum (1D, D₂O, experimental)	Spectrum
1D NMR	¹³C NMR Spectrum (1D, 100 MHz, D₂O, predicted)	Spectrum
1D NMR	¹H NMR Spectrum (1D, 100 MHz, D₂O, predicted)	Spectrum
1D NMR	¹³C NMR Spectrum (1D, 1000 MHz, D₂O, predicted)	Spectrum
1D NMR	¹H NMR Spectrum (1D, 1000 MHz, D₂O, predicted)	Spectrum
1D NMR	¹³C NMR Spectrum (1D, 200 MHz, D₂O, predicted)	Spectrum
1D NMR	¹H NMR Spectrum (1D, 200 MHz, D₂O, predicted)	Spectrum
1D NMR	¹³C NMR Spectrum (1D, 300 MHz, D₂O, predicted)	Spectrum
1D NMR	¹H NMR Spectrum (1D, 300 MHz, D₂O, predicted)	Spectrum
1D NMR	¹³C NMR Spectrum (1D, 400 MHz, D₂O, predicted)	Spectrum
1D NMR	¹H NMR Spectrum (1D, 400 MHz, D₂O, predicted)	Spectrum
1D NMR	¹³C NMR Spectrum (1D, 500 MHz, D₂O, predicted)	Spectrum
1D NMR	¹H NMR Spectrum (1D, 500 MHz, D₂O, predicted)	Spectrum
1D NMR	¹³C NMR Spectrum (1D, 600 MHz, D₂O, predicted)	Spectrum
1D NMR	¹H NMR Spectrum (1D, 600 MHz, D₂O, predicted)	Spectrum
1D NMR	¹³C NMR Spectrum (1D, 700 MHz, D₂O, predicted)	Spectrum
1D NMR	¹H NMR Spectrum (1D, 700 MHz, D₂O, predicted)	Spectrum
1D NMR	¹³C NMR Spectrum (1D, 800 MHz, D₂O, predicted)	Spectrum
1D NMR	¹H NMR Spectrum (1D, 800 MHz, D₂O, predicted)	Spectrum
1D NMR	¹³C NMR Spectrum (1D, 900 MHz, D₂O, predicted)	Spectrum
1D NMR	¹H NMR Spectrum (1D, 900 MHz, D₂O, predicted)	Spectrum
2D NMR	[¹H, ¹H]-TOCSY. Unexported temporarily by An Chi on Oct 15, 2021 until json or nmrML file is generated. 2D NMR Spectrum (experimental)	Spectrum
2D NMR	[¹H, ¹³C]-HSQC NMR Spectrum (2D, 600 MHz, H₂O, experimental)	Spectrum

Pathways

Name	SMPDB/Pathwhiz	KEGG
Nicotinate and Nicotinamide Metabolism

Protein Targets

Enzymes

Protein Name	Gene Name	Locus	Uniprot ID	Details
Nicotinate-nucleotide pyrophosphorylase [carboxylating]	QPRT	16p11.2	Q15274	details
Nicotinamide N-methyltransferase	NNMT	11q23.1	P40261	details
G-protein coupled receptor 109B	GPR109B	12q24.31	P49019	details
G-protein coupled receptor 109A	GPR109A	12q24.31	Q8TDS4	details
Purine nucleoside phosphorylase	PNP	14q13.1	P00491	details
Nicotinate phosphoribosyltransferase	NAPRT1	8q24.3	Q6XQN6	details

Transporters

Protein Name	Gene Name	Locus	Uniprot ID	Details
Monocarboxylate transporter 1	SLC16A1	1p12	P53985	details
Solute carrier family 22 member 5	SLC22A5	5q31	O76082	details
Solute carrier organic anion transporter family member 2B1	SLCO2B1	11q13	O94956	details

Metal Bindings

Protein Name	Gene Name	Locus	Uniprot ID	Details
Cytochrome P450 2D6	CYP2D6	22q13.1	P10635	details

Receptors

Protein Name	Gene Name	Locus	Uniprot ID	Details
G-protein coupled receptor 109B	GPR109B	12q24.31	P49019	details
G-protein coupled receptor 109A	GPR109A	12q24.31	Q8TDS4	details

Transcriptional Factors

Not Available

Concentrations Data

Not Available

External Links

HMDB ID

HMDB0001488

DrugBank ID

DB00627

Phenol Explorer Compound ID

Not Available

FoodDB ID

KNApSAcK ID

Chemspider ID

KEGG Compound ID

BioCyc ID

BiGG ID

Wikipedia Link

METLIN ID

PubChem Compound

PDB ID

Not Available

ChEBI ID

15940

References

General References

Not Available

Only showing the first 10 proteins. There are 12 proteins in total.

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Enzymes

Enzyme Details

1. Nicotinate-nucleotide pyrophosphorylase [carboxylating]

General function:: Involved in catalytic activity
Specific function:: Involved in the catabolism of quinolinic acid (QA).
Gene Name:: QPRT
Uniprot ID:: Q15274
Molecular weight:: 30815.28

Enzyme Details

2. Nicotinamide N-methyltransferase

General function:: Involved in methyltransferase activity
Specific function:: Catalyzes the N-methylation of nicotinamide and other pyridines to form pyridinium ions. This activity is important for biotransformation of many drugs and xenobiotic compounds.
Gene Name:: NNMT
Uniprot ID:: P40261
Molecular weight:: 29573.705

Enzyme Details

3. G-protein coupled receptor 109B

General function:: Involved in G-protein coupled receptor protein signaling pathway
Specific function:: Receptor for 3-OH-octanoid acid mediates a negative feedback regulation of adipocyte lipolysis to counteract prolipolytic influences under conditions of physiological or pathological increases in beta-oxidation rates. Acts as a low affinity receptor for nicotinic acid. This pharmacological effect requires nicotinic acid doses that are much higher than those provided by a normal diet
Gene Name:: GPR109B
Uniprot ID:: P49019
Molecular weight:: 44495.0

Enzyme Details

4. G-protein coupled receptor 109A

General function:: Involved in G-protein coupled receptor protein signaling pathway
Specific function:: Acts as a high affinity receptor for both nicotinic acid (also known as niacin) and (D)-beta-hydroxybutyrate and mediates increased adiponectin secretion and decreased lipolysis through G(i)-protein-mediated inhibition of adenylyl cyclase. This pharmacological effect requires nicotinic acid doses that are much higher than those provided by a normal diet. Mediates nicotinic acid-induced apoptosis in mature neutrophils. Receptor activation by nicotinic acid results in reduced cAMP levels which may affect activity of cAMP-dependent protein kinase A and phosphorylation of target proteins, leading to neutrophil apoptosis. The rank order of potency for the displacement of nicotinic acid binding is 5- methyl pyrazole-3-carboxylic acid = pyridine-3-acetic acid > acifran > 5-methyl nicotinic acid = acipimox >> nicotinuric acid = nicotinamide
Gene Name:: GPR109A
Uniprot ID:: Q8TDS4
Molecular weight:: 41849.1

Enzyme Details

5. Purine nucleoside phosphorylase

General function:: Involved in purine-nucleoside phosphorylase activity
Specific function:: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
Gene Name:: PNP
Uniprot ID:: P00491
Molecular weight:: 32117.69

Enzyme Details

6. Nicotinate phosphoribosyltransferase

General function:: Involved in nicotinate phosphoribosyltransferase activity
Specific function:: Catalyzes the conversion of nicotinic acid (NA) to NA mononucleotide (NaMN). Essential for NA to increase cellular NAD levels and prevent oxidative stress of the cells.
Gene Name:: NAPRT1
Uniprot ID:: Q6XQN6
Molecular weight:: 57577.575

Transporters

Enzyme Details

1. Monocarboxylate transporter 1

General function:: Involved in transmembrane transport
Specific function:: Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate
Gene Name:: SLC16A1
Uniprot ID:: P53985
Molecular weight:: 53957.7

Enzyme Details

2. Solute carrier family 22 member 5

General function:: Involved in ion transmembrane transporter activity
Specific function:: Sodium-ion dependent, high affinity carnitine transporter. Involved in the active cellular uptake of carnitine. Transports one sodium ion with one molecule of carnitine. Also transports organic cations such as tetraethylammonium (TEA) without the involvement of sodium. Also relative uptake activity ratio of carnitine to TEA is 11.3
Gene Name:: SLC22A5
Uniprot ID:: O76082
Molecular weight:: 62751.1

Enzyme Details

3. Solute carrier organic anion transporter family member 2B1

General function:: Involved in transporter activity
Specific function:: Mediates the Na(+)-independent transport of organic anions such as taurocholate, the prostaglandins PGD2, PGE1, PGE2, leukotriene C4, thromboxane B2 and iloprost
Gene Name:: SLCO2B1
Uniprot ID:: O94956
Molecular weight:: 76697.9

Only showing the first 10 proteins. There are 12 proteins in total.

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Showing Compound Card for Nicotinic acid (CDB004918)

Structure for CDB004918 (Nicotinic acid)

Enzymes

Transporters