| Identification |
|---|
| HMDB Protein ID
| CDBP02058 |
| Secondary Accession Numbers
| Not Available |
| Name
| Agmatinase, mitochondrial |
| Description
| Not Available |
| Synonyms
|
- AUH
- Agmatine ureohydrolase
|
| Gene Name
| AGMAT |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in agmatinase activity |
| Specific Function
| Not Available |
| GO Classification
|
| Biological Process |
| putrescine biosynthetic process from arginine |
| polyamine metabolic process |
| spermidine biosynthetic process |
| small molecule metabolic process |
| agmatine biosynthetic process |
| Cellular Component |
| mitochondrion |
| Function |
| ion binding |
| cation binding |
| metal ion binding |
| binding |
| catalytic activity |
| hydrolase activity |
| hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines |
| hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds |
| agmatinase activity |
| Molecular Function |
| metal ion binding |
| agmatinase activity |
| Process |
| cellular metabolic process |
| cellular amino acid derivative metabolic process |
| cellular biogenic amine metabolic process |
| polyamine metabolic process |
| polyamine biosynthetic process |
| cellular amino acid and derivative metabolic process |
| metabolic process |
|
| Cellular Location
|
- Mitochondrion
|
| Pathways
|
| Name | SMPDB/Pathwhiz | KEGG | | putrescine biosynthesis via agmatine pathway | Not Available | Not Available |
|
| Gene Properties |
|---|
| Chromosome Location
| 1 |
| Locus
| 1p36.21 |
| SNPs
| AGMAT |
| Gene Sequence
|
>1059 bp
ATGCTGAGGCTGCTGGCGTCCGGGTGCGCCCGGGGCCCGGGGCCCGGCGTGGGCGCGCGT
CCTGCCGCAGGGCTCTTTCATCCGGGGCGCCGCCAGAGCCGCCAGGCTTCCGATGCGCCC
CGGAACCAGCCCCCCAGCCCCGAGTTCGTGGCCCGGCCGGTGGGCGTCTGCTCCATGATG
CGCCTGCCGGTGCAGACCTCCCCCGAGGGGCTGGACGCTGCCTTCATCGGGGTGCCCCTG
GATACTGGGACCTCCAACCGGCCTGGGGCGAGATTCGGACCTCGCCGCATCCGGGAAGAA
TCAGTGATGCTTCGGACAGTCAATCCTAGCACGGGGGCCCTCCCCTTCCAGTCCCTCATG
GTTGCAGACCTAGGCGATGTGAATGTCAATCTTTACAACCTTCAGGACAGCTGCCGGCGA
ATTCAAGAGGCCTGTGAGAAAATTGTAGCAGCTGGCTGTATTCCTCTGACCTTGGGTGGA
GATCACACAATCACATATCCCATATTGCAAGCGATGGCAAAAAAGCATGGCCCAGTGGGG
CTGCTGCACGTGGATGCGCACACGGACACGACCGACAAGGCCCTAGGAGAGAAGCTCTAC
CACGGGGCGCCCTTCCGCCGGTGTGTGGATGAGGGTCTCCTGGACTGTAAGCGTGTGGTG
CAGATTGGCATCCGGGGCTCTTCCACGACCTTGGATCCCTACAGATACAACCGGAGCCAG
GGCTTCCGGGTAGTCCTGGCTGAAGACTGCTGGATGAAGTCGCTGGTTCCTCTGATGGGG
GAAGTCAGGCAGCAGATGGGAGGCAAACCCATTTATATCAGCTTTGATATTGACGCTCTG
GATCCTGCCTATGCGCCAGGGACAGGGACACCTGAAATTGCTGGTCTCACTCCTAGTCAG
GCTCTGGAGATCATCAGGGGTTGTCAAGGCCTGAACGTGATGGGCTGTGATCTTGTCGAA
GTTTCACCACCGTATGATCTTTCTGGGAACACAGCCCTGCTGGCGGCTAACCTGCTGTTT
GAGATGCTATGTGCTCTCCCCAAAGTGACAACCGTCTGA
|
| Protein Properties |
|---|
| Number of Residues
| 352 |
| Molecular Weight
| 37660.065 |
| Theoretical pI
| 7.597 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Agmatinase, mitochondrial
MLRLLASGCARGPGPGVGARPAAGLFHPGRRQSRQASDAPRNQPPSPEFVARPVGVCSMM
RLPVQTSPEGLDAAFIGVPLDTGTSNRPGARFGPRRIREESVMLGTVNPSTGALPFQSLM
VADLGDVNVNLYNLQDSCRRIQEAYEKIVAAGCIPLTLGGDHTITYPILQAMAKKHGPVG
LLHVDAHTDTTDKALGEKLYHGAPFRRCVDEGLLDCKRVVQIGIRGSSTTLDPYRYNRSQ
GFRVVLAEDCWMKSLVPLMGEVRQQMGGKPIYISFDIDALDPAYAPGTGTPEIAGLTPSQ
ALEIIRGCQGLNVMGCDLVEVSPPYDLSGNTALLAANLLFEMLCALPKVTTV
|
| External Links |
|---|
| GenBank ID Protein
| 10440052 |
| UniProtKB/Swiss-Prot ID
| Q9BSE5 |
| UniProtKB/Swiss-Prot Entry Name
| SPEB_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AK027037 |
| GeneCard ID
| AGMAT |
| GenAtlas ID
| AGMAT |
| HGNC ID
| HGNC:18407 |
| References |
|---|
| General References
| Not Available |