| Identification |
|---|
| HMDB Protein ID
| CDBP01860 |
| Secondary Accession Numbers
| Not Available |
| Name
| Phosphatidylserine decarboxylase proenzyme |
| Description
| Not Available |
| Synonyms
|
- Phosphatidylserine decarboxylase alpha chain
- Phosphatidylserine decarboxylase beta chain
- SubName: Phosphatidylserine decarboxylase, isoform CRA_a
|
| Gene Name
| PISD |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in phosphatidylserine decarboxylase activity |
| Specific Function
| Not Available |
| GO Classification
|
| Biological Process |
| small molecule metabolic process |
| phosphatidylethanolamine biosynthetic process |
| Cellular Component |
| mitochondrion |
| nucleus |
| Function |
| catalytic activity |
| lyase activity |
| carbon-carbon lyase activity |
| carboxy-lyase activity |
| phosphatidylserine decarboxylase activity |
| Molecular Function |
| phosphatidylserine decarboxylase activity |
| Process |
| metabolic process |
| phospholipid biosynthetic process |
| organophosphate metabolic process |
| phospholipid metabolic process |
|
| Cellular Location
|
- Mitochondrion
|
| Pathways
|
| Name | SMPDB/Pathwhiz | KEGG | | Phospholipid Biosynthesis |    |  | | Glycerophospholipid metabolism | Not Available | | | Phosphatidylcholine Biosynthesis |    | Not Available | | Phosphatidylcholine Biosynthesis PC(14:0/14:0) |    | Not Available | | Phosphatidylcholine Biosynthesis PC(14:0/14:1(9Z)) |    | Not Available |
|
| Gene Properties |
|---|
| Chromosome Location
| 22 |
| Locus
| 22q12.2 |
| SNPs
| PISD |
| Gene Sequence
|
>1128 bp
ATGATGTGTCAGTCAGAGGCGCGGCAAGGACCAGAGCTCCGCGCGGCGAAATGGTTGCAC
TTCCCCCAGCTGGCCCTGAGGCGGAGGCTGGGGCAGCTGAGCTGCATGTCCAGACCCGCT
CTGAAACTGCGCTCCTGGCCCTTGACCGTCCTCTACTACCTCCTGCCCTTCGGCGCCCTC
AGACCGCTCAGCCGGGTGGGATGGAGGCCCGTAAGCAGGGTGGCTTTGTACAAGTCAGTG
CCAACGCGCTTGCTGTCACGGGCCTGGGGTCGCCTCAATCAGGTGGAGCTGCCACACTGG
CTGCGCAGGCCCGTCTACAGCCTGTACATCTGGACGTTTGGGGTGAACATGAAAGAGGCC
GCTGTGGAGGACCTGCATCACTACCGCAACCTCAGCGAGTTCTTCCGGCGCAAGCTGAAG
CCGCAGGCCCGGCCTGTCTGTGGCCTGCACAGCGTGATTAGCCCATCGGATGGAAGGATC
CTCAACTTTGGGCAGGTGAAGAACTGTGAGGTGGAGCAGGTAAAGGGGGTCACCTACTCC
CTGGAGTCGTTCCTGGGCCCGCGTATGTGCACAGAGGACCTGCCCTTCCCACCAGCCGCG
TCGTGTGACTCCTTCAAGAACCAGCTGGTCACCCGGGAAGGGAATGAGCTCTATCACTGT
GTCATCTACCTGGCCCCTGGGGACTACCACTGCTTCCACTCCCCCACCGACTGGACTGTG
TCCCACCGGCGCCACTTCCCAGGCTCCCTGATGTCAGTGAACCCTGGCATGGCTCGCTGG
ATCAAAGAGCTCTTCTGCCATAACGAGCGGGTGGTCCTGACGGGGGACTGGAAACATGGC
TTCTTCTCACTGACAGCTGTGGGGGCCACCAACGTGGGCTCCATTCGCATCTACTTTGAC
CGGGACCTGCACACAAACAGCCCAAGGCACAGCAAGGGCTCCTACAATGACTTCAGCTTC
GTGACGCACACCAATAGAGAGGGCGTCCCCATGCGTAAGGGCGAGCACCTGGGCGAGTTC
AACCTGGGCTCCACCATCGTGCTCATCTTCGAGGCCCCCAAGGACTTCAATTTCCAGCTG
AAAACAGGACAGAAAATCCGCTTTGGGGAAGCCCTGGGCTCGCTCTAG
|
| Protein Properties |
|---|
| Number of Residues
| 408 |
| Molecular Weight
| 43046.33 |
| Theoretical pI
| 9.703 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Phosphatidylserine decarboxylase proenzyme
MATSVGHRCLGLLHGVAPWRSSLHPCEITALSQSLQPLRKLPFRAFRTDARKIHTAPART
MFLLRPLPILLVTGGGYAGYRQYEKYRERELEKLGLEIPPKLAGHWEVALYKSVPTRLLS
RAWGRLNQVELPHWLRRPVYSLYIWTFGVNMKEAAVEDLHHYRNLSEFFRRKLKPQARPV
CGLHSISPSDGRILNFGQVKNCEVEQVKGVTYSLESFLGPRMCTEDLPFPPAASCDSFKN
QLVTREGNELYHCVIYLAPGDYHCFHSPTDWTVSHRRHFPGSLMSVNPGMARWIKELFCH
NERVVLTGDWKHGFFSLTAVGATNVGSIRIYFDRDLHTNSPRHSKGSYNDFSFVTHTNRE
GVPMRKGEHLGEFNLGSTIVLIFEAPKDFNFQLKTGQKIRFGEALGSL
|
| External Links |
|---|
| GenBank ID Protein
| 13489112 |
| UniProtKB/Swiss-Prot ID
| Q9UG56 |
| UniProtKB/Swiss-Prot Entry Name
| PISD_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_014338 |
| GeneCard ID
| PISD |
| GenAtlas ID
| PISD |
| HGNC ID
| HGNC:8999 |
| References |
|---|
| General References
| Not Available |