| Identification |
|---|
| HMDB Protein ID
| CDBP01060 |
| Secondary Accession Numbers
| Not Available |
| Name
| Acyl-CoA:lysophosphatidylglycerol acyltransferase 1 |
| Description
| Not Available |
| Synonyms
|
Not Available
|
| Gene Name
| LPGAT1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in acyltransferase activity |
| Specific Function
| Lysophoshatidylglycerol (LPG) specific acyltransferase that recognizes various acyl-CoAs and LPGs as substrates but demonstrates a clear preference for long chain saturated fatty acyl-CoAs and oleoyl-CoA as acyl donors. Prefers oleoyl-LPG over palmitoyl-LPG as an acyl receptor and oleoyl-CoA over lauroyl-CoA as an acyl donor |
| GO Classification
|
| Function |
| catalytic activity |
| transferase activity |
| transferase activity, transferring acyl groups |
| transferase activity, transferring acyl groups other than amino-acyl groups |
| acyltransferase activity |
| Process |
| metabolic process |
|
| Cellular Location
|
- Endoplasmic reticulum membrane
- Multi-pass membrane protein
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 1q32 |
| SNPs
| LPGAT1 |
| Gene Sequence
|
>1113 bp
ATGGCTATAACTTTGGAAGAAGCTCCGTGGCTGGGCTGGCTCTTGGTGAAAGCACTGATG
AGGTTTGCCTTCATGGTCGTCAACAACCTGGTTGCTATTCCATCCTACATCTGCTATGTA
ATTATACTTCAGCCCCTTCGAGTGCTGGACAGTAAGCGGTTCTGGTATATCGAAGGAATC
ATGTATAAATGGCTTTTAGGAATGGTAGCTTCCTGGGGATGGTATGCTGGATATACAGTG
ATGGAATGGGGAGAAGATATTAAAGCAGTTTCAAAAGATGAAGCAGTGATGTTGGTGAAT
CATCAGGCAACAGGAGATGTGTGCACACTGATGATGTGCCTCCAGGACAAAGGACTGGTT
GTTGCTCAGATGATGTGGTTGATGGATCATATTTTTAAGTACACAAACTTTGGAATTGTT
TCTCTAGTTCATGGAGACTTCTTTATAAGACAGGGAAGATCTTATCGTGACCAACAGCTG
CTGCTTCTCAAGAAGCACTTAGAAAATAATTACAGGAGCAGAGATCGAAAATGGATTGTT
TTGTTTCCAGAAGGGGGCTTCCTCAGGAAGAGGCGAGAAACAAGTCAGGCATTTGCCAAG
AAAAATAACTTGCCATTTCTTACAAATGTTACTCTGCCAAGGTCTGGGGCAACAAAAATT
ATTTTGAATGCACTTGTAGCACAACAGAAAAATGGAAGTCCAGCAGGAGGAGATGCTAAA
GAATTAGACAGCAAATCAAAAGGCCTCCAGTGGATAATAGATACAACGATAGCTTATCCC
AAAGCTGAACCTATAGATATTCAAACCTGGATCCTTGGATACAGGAAACCAACAGTCACA
CATGTACATTACAGGATCTTTCCAATTAAAGATGTACCCCTGGAGACTGATGACCTTACC
ACTTGGCTCTATCAGCGGTTTGTTGAAAAAGAAGACCTCTTATCACATTTTTATGAAACA
GGAGCTTTTCCACCTTCCAAGGGCCATAAGGAAGCTGTTTCCAGGGAGATGACCCTCAGC
AACTTGTGGATATTTCTCATACAGTCTTTTGCATTTTTGTCAGGCTATATGTGGTACAAC
ATCATTCAGTATTTTTACCATTGCCTGTTTTAG
|
| Protein Properties |
|---|
| Number of Residues
| 370 |
| Molecular Weight
| 43089.1 |
| Theoretical pI
| 9.24 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Acyl-CoA:lysophosphatidylglycerol acyltransferase 1
MAITLEEAPWLGWLLVKALMRFAFMVVNNLVAIPSYICYVIILQPLRVLDSKRFWYIEGI
MYKWLLGMVASWGWYAGYTVMEWGEDIKAVSKDEAVMLVNHQATGDVCTLMMCLQDKGLV
VAQMMWLMDHIFKYTNFGIVSLVHGDFFIRQGRSYRDQQLLLLKKHLENNYRSRDRKWIV
LFPEGGFLRKRRETSQAFAKKNNLPFLTNVTLPRSGATKIILNALVAQQKNGSPAGGDAK
ELDSKSKGLQWIIDTTIAYPKAEPIDIQTWILGYRKPTVTHVHYRIFPIKDVPLETDDLT
TWLYQRFVEKEDLLSHFYETGAFPPSKGHKEAVSREMTLSNLWIFLIQSFAFLSGYMWYN
IIQYFYHCLF
|
| External Links |
|---|
| GenBank ID Protein
| 22902215 |
| UniProtKB/Swiss-Prot ID
| Q92604 |
| UniProtKB/Swiss-Prot Entry Name
| LGAT1_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC034621 |
| GeneCard ID
| LPGAT1 |
| GenAtlas ID
| LPGAT1 |
| HGNC ID
| HGNC:28985 |
| References |
|---|
| General References
| Not Available |