Identification
HMDB Protein ID CDBP05650
Secondary Accession Numbers Not Available
Name Neural cell adhesion molecule 1
Description Not Available
Synonyms Not Available
Gene Name NCAM1
Protein Type Receptor
Biological Properties
General Function virus receptor activity
Specific Function This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc.(Microbial infection) Acts as a receptor for rabies virus.
GO Classification
Biological Process
commissural neuron axon guidance
cell adhesion
regulation of semaphorin-plexin signaling pathway
interferon-gamma-mediated signaling pathway
axon guidance
MAPK cascade
Cellular Component
membrane
neuron projection
integral to membrane
Golgi membrane
collagen-containing extracellular matrix
cytosol
cell surface
anchored to membrane
plasma membrane
external side of plasma membrane
Molecular Function
viral receptor activity
identical protein binding
Cellular Location
  1. Cell membrane
  2. Secreted
Pathways
Gene Properties
Chromosome Location 11
Locus 11q23.2
SNPs Not Available
Gene Sequence Not Available
Protein Properties
Number of Residues 848
Molecular Weight 94573.465
Theoretical pI Not Available
Pfam Domain Function
Signals
  • ["1-19"]
Transmembrane Regions
  • ["719-739"]
Protein Sequence
>Neural cell adhesion molecule 1
MLQTKDLIWTLFFLGTAVSLQVDIVPSQGEISVGESKFFLCQVAGDAKDKDISWFSPNGE
KLTPNQQRISVVWNDDSSSTLTIYNANIDDAGIYKCVVTGEDGSESEATVNVKIFQKLMF
KNAPTPQEFREGEDAVIVCDVVSSLPPTIIWKHKGRDVILKKDVRFIVLSNNYLQIRGIK
KTDEGTYRCEGRILARGEINFKDIQVIVNVPPTIQARQNIVNATANLGQSVTLVCDAEGF
PEPTMSWTKDGEQIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAEYICIAENKAGEQDATI
HLKVFAKPKITYVENQTAMELEEQVTLTCEASGDPIPSITWRTSTRNISSEEKASWTRPE
KQETLDGHMVVRSHARVSSLTLKSIQYTDAGEYICTASNTIGQDSQSMYLEVQYAPKLQG
PVAVYTWEGNQVNITCEVFAYPSATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDS
ENDFGNYNCTAVNRIGQESLEFILVQADTPSSPSIDQVEPYSSTAQVQFDEPEATGGVPI
LKYKAEWRAVGEEVWHSKWYDAKEASMEGIVTIVGLKPETTYAVRLAALNGKGLGEISAA
SEFKTQPVQGEPSAPKLEGQMGEDGNSIKVNLIKQDDGGSPIRHYLVRYRALSSEWKPEI
RLPSGSDHVMLKSLDWNAEYEVYVVAENQQGKSKAAHFVFRTSAQPTAIPANGSPTSGLS
TGAIVGILIVIFVLLLVVVDITCYFLNKCGLFMCIAVNLCGKAGPGAKGKDMEEGKAAFS
KDESKEPIVEVRTEEERTPNHDGGKHTEPNETTPLTEPEKGPVEAKPECQETETKPAPAE
VKTVPNDATQTKENESKA
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID P13591
UniProtKB/Swiss-Prot Entry Name NCAM1_HUMAN
PDB IDs
GenBank Gene ID Not Available
GeneCard ID Not Available
GenAtlas ID Not Available
HGNC ID HGNC:7656
References
General References Not Available