Identification
HMDB Protein ID CDBP05635
Secondary Accession Numbers Not Available
Name Involucrin
Description Not Available
Synonyms Not Available
Gene Name IVL
Protein Type Enzyme
Biological Properties
General Function Not Available
Specific Function Part of the insoluble cornified cell envelope (CE) of stratified squamous epithelia.
GO Classification
Biological Process
cornification
response to UV-B
keratinocyte differentiation
peptide cross-linking
isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine
Cellular Component
cytoplasm
extracellular vesicular exosome
nuclear body
cornified envelope
cytosol
centrosome
Cellular Location
  1. Cytoplasm
Pathways
Gene Properties
Chromosome Location 1
Locus 1q21.3
SNPs Not Available
Gene Sequence Not Available
Protein Properties
Number of Residues 585
Molecular Weight 68478.89
Theoretical pI Not Available
Pfam Domain Function
Signals Not Available
Transmembrane Regions Not Available
Protein Sequence
>Involucrin
MSQQHTLPVTLSPALSQELLKTVPPPVNTHQEQMKQPTPLPPPCQKVPVELPVEVPSKQE
EKHMTAVKGLPEQECEQQQKEPQEQELQQQHWEQHEEYQKAENPEQQLKQEKTQRDQQLN
KQLEEEKKLLDQQLDQELVKRDEQLGMKKEQLLELPEQQEGHLKHLEQQEGQLKHPEQQE
GQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPQQQE
GQLELSEQQEGQLELSEQQEGQLKHLEHQEGQLEVPEEQMGQLKYLEQQEGQLKHLDQQE
KQPELPEQQMGQLKHLEQQEGQPKHLEQQEGQLEQLEEQEGQLKHLEQQEGQLEHLEHQE
GQLGLPEQQVLQLKQLEKQQGQPKHLEEEEGQLKHLVQQEGQLKHLVQQEGQLEQQERQV
EHLEQQVGQLKHLEEQEGQLKHLEQQQGQLEVPEQQVGQPKNLEQEEKQLELPEQQEGQV
KHLEKQEAQLELPEQQVGQPKHLEQQEKHLEHPEQQDGQLKHLEQQEGQLKDLEQQKGQL
EQPVFAPAPGQVQDIQPALPTKGEVLLPVEHQQQKQEVQWPPKHK
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID P07476
UniProtKB/Swiss-Prot Entry Name INVO_HUMAN
PDB IDs
GenBank Gene ID Not Available
GeneCard ID Not Available
GenAtlas ID Not Available
HGNC ID HGNC:6187
References
General References Not Available