Identification |
HMDB Protein ID
| CDBP05635 |
Secondary Accession Numbers
| Not Available |
Name
| Involucrin |
Description
| Not Available |
Synonyms
|
Not Available
|
Gene Name
| IVL |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Not Available |
Specific Function
| Part of the insoluble cornified cell envelope (CE) of stratified squamous epithelia. |
GO Classification
|
Biological Process |
cornification |
response to UV-B |
keratinocyte differentiation |
peptide cross-linking |
isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine |
Cellular Component |
cytoplasm |
extracellular vesicular exosome |
nuclear body |
cornified envelope |
cytosol |
centrosome |
|
Cellular Location
|
- Cytoplasm
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| 1 |
Locus
| 1q21.3 |
SNPs
| Not Available |
Gene Sequence
|
Not Available
|
Protein Properties |
Number of Residues
| 585 |
Molecular Weight
| 68478.89 |
Theoretical pI
| Not Available |
Pfam Domain Function
|
|
Signals
|
Not Available
|
Transmembrane Regions
|
Not Available
|
Protein Sequence
|
>Involucrin
MSQQHTLPVTLSPALSQELLKTVPPPVNTHQEQMKQPTPLPPPCQKVPVELPVEVPSKQE
EKHMTAVKGLPEQECEQQQKEPQEQELQQQHWEQHEEYQKAENPEQQLKQEKTQRDQQLN
KQLEEEKKLLDQQLDQELVKRDEQLGMKKEQLLELPEQQEGHLKHLEQQEGQLKHPEQQE
GQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPQQQE
GQLELSEQQEGQLELSEQQEGQLKHLEHQEGQLEVPEEQMGQLKYLEQQEGQLKHLDQQE
KQPELPEQQMGQLKHLEQQEGQPKHLEQQEGQLEQLEEQEGQLKHLEQQEGQLEHLEHQE
GQLGLPEQQVLQLKQLEKQQGQPKHLEEEEGQLKHLVQQEGQLKHLVQQEGQLEQQERQV
EHLEQQVGQLKHLEEQEGQLKHLEQQQGQLEVPEQQVGQPKNLEQEEKQLELPEQQEGQV
KHLEKQEAQLELPEQQVGQPKHLEQQEKHLEHPEQQDGQLKHLEQQEGQLKDLEQQKGQL
EQPVFAPAPGQVQDIQPALPTKGEVLLPVEHQQQKQEVQWPPKHK
|
External Links |
GenBank ID Protein
| Not Available |
UniProtKB/Swiss-Prot ID
| P07476 |
UniProtKB/Swiss-Prot Entry Name
| INVO_HUMAN |
PDB IDs
|
|
GenBank Gene ID
| Not Available |
GeneCard ID
| Not Available |
GenAtlas ID
| Not Available |
HGNC ID
| HGNC:6187 |
References |
General References
| Not Available |