Identification
HMDB Protein ID CDBP05624
Secondary Accession Numbers Not Available
Name Taste receptor type 2 member 38
Description Not Available
Synonyms Not Available
Gene Name TAS2R38
Protein Type Receptor
Biological Properties
General Function G protein-coupled receptor activity
Specific Function Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity).
GO Classification
Biological Process
G-protein coupled receptor signaling pathway
detection of chemical stimulus involved in sensory perception of bitter taste
Cellular Component
plasma membrane
integral to membrane
Molecular Function
bitter taste receptor activity
G protein-coupled receptor activity
Cellular Location
  1. Membrane
Pathways
Gene Properties
Chromosome Location 7
Locus 7q34
SNPs Not Available
Gene Sequence Not Available
Protein Properties
Number of Residues 333
Molecular Weight 37891.97
Theoretical pI Not Available
Pfam Domain Function
Signals Not Available
Transmembrane Regions
  • ["18-38", "56-76", "95-115", "143-163", "191-211", "252-272", "277-297"]
Protein Sequence
>Taste receptor type 2 member 38
MLTLTRIRTVSYEVRSTFLFISVLEFAVGFLTNAFVFLVNFWDVVKRQALSNSDCVLLCL
SISRLFLHGLLFLSAIQLTHFQKLSEPLNHSYQAIIMLWMIANQANLWLAACLSLLYCSK
LIRFSHTFLICLASWVSRKISQMLLGIILCSCICTVLCVWCFFSRPHFTVTTVLFMNNNT
RLNWQIKDLNLFYSFLFCYLWSVPPFLLFLVSSGMLTVSLGRHMRTMKVYTRNSRDPSLE
AHIKALKSLVSFFCFFVISSCAAFISVPLLILWRDKIGVMVCVGIMAACPSGHAAILISG
NAKLRRAVMTILLWAQSSLKVRADHKADSRTLC
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID P59533
UniProtKB/Swiss-Prot Entry Name T2R38_HUMAN
PDB IDs Not Available
GenBank Gene ID Not Available
GeneCard ID Not Available
GenAtlas ID Not Available
HGNC ID HGNC:9584
References
General References Not Available