Identification |
HMDB Protein ID
| CDBP05539 |
Secondary Accession Numbers
| Not Available |
Name
| U5 small nuclear ribonucleoprotein 200 kDa helicase |
Description
| Not Available |
Synonyms
|
- Activating signal cointegrator 1 complex subunit 3-like 1
- BRR2 homolog
- U5 snRNP-specific 200 kDa protein
- U5-200KD
|
Gene Name
| SNRNP200 |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Not Available |
Specific Function
| Putative RNA helicase involved in the second step of RNA splicing. May promote one or more conformational changes in the dynamic network of RNA-RNA interactions in the spliceosome. Appears to catalyze an ATP-dependent unwinding of U4/U6 RNA duplices.
|
GO Classification
|
Biological Process |
cis assembly of pre-catalytic spliceosome |
Cellular Component |
nucleoplasm |
catalytic step 2 spliceosome |
U5 snRNP |
Molecular Function |
nucleic acid binding |
ATP binding |
ATP-dependent helicase activity |
|
Cellular Location
|
Not Available
|
Pathways
|
Name | SMPDB/Pathwhiz | KEGG | Spliceosome | Not Available | |
|
Gene Properties |
Chromosome Location
| 2 |
Locus
| 2q11.2 |
SNPs
| Not Available |
Gene Sequence
|
Not Available
|
Protein Properties |
Number of Residues
| Not Available |
Molecular Weight
| 244505.465 |
Theoretical pI
| 6.067 |
Pfam Domain Function
|
Not Available |
Signals
|
Not Available
|
Transmembrane Regions
|
Not Available
|
Protein Sequence
|
>gi|40217847|ref|NP_054733.2| U5 small nuclear ribonucleoprotein 200 kDa helicase [Homo sapiens]
MADVTARSLQYEYKANSNLVLQADRSLIDRTRRDEPTGEVLSLVGKLEGTRMGDKAQRTK
PQMQEERRAK
|
External Links |
GenBank ID Protein
| Not Available |
UniProtKB/Swiss-Prot ID
| O75643 |
UniProtKB/Swiss-Prot Entry Name
| Not Available |
PDB IDs
|
|
GenBank Gene ID
| Not Available |
GeneCard ID
| Not Available |
GenAtlas ID
| Not Available |
HGNC ID
| HGNC:30859 |
References |
General References
| Not Available |