Identification
HMDB Protein ID CDBP05470
Secondary Accession Numbers Not Available
Name DNA-directed RNA polymerase II subunit RPB11-a
Description Not Available
Synonyms
  1. RNA polymerase II subunit B11-a
  2. RPB11a
  3. DNA-directed RNA polymerase II subunit J-1
  4. RNA polymerase II 13.3 kDa subunit
Gene Name POLR2J
Protein Type Enzyme
Biological Properties
General Function Not Available
Specific Function DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB11 is part of the core element with the central large cleft (By similarity).
GO Classification
Biological Process
mRNA splicing, via spliceosome
viral reproduction
protein phosphorylation
positive regulation of viral transcription
transcription elongation from RNA polymerase II promoter
transcription initiation from RNA polymerase II promoter
transcription-coupled nucleotide-excision repair
7-methylguanosine mRNA capping
Cellular Component
DNA-directed RNA polymerase II, core complex
Molecular Function
DNA-directed RNA polymerase activity
DNA binding
Cellular Location Not Available
Pathways
Gene Properties
Chromosome Location 7
Locus 7q22.1
SNPs Not Available
Gene Sequence Not Available
Protein Properties
Number of Residues Not Available
Molecular Weight 13293.19
Theoretical pI 5.861
Pfam Domain Function Not Available
Signals Not Available
Transmembrane Regions Not Available
Protein Sequence
>gi|5453932|ref|NP_006225.1| DNA-directed RNA polymerase II subunit RPB11-a [Homo sapiens]
MNAPPAFESFLLFEGEKKITINKDTKVPNACLFTINKEDHTLGNIIKSQLLKDPQVLFAG
YKVPHPLEHK
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID P52435
UniProtKB/Swiss-Prot Entry Name Not Available
PDB IDs Not Available
GenBank Gene ID Not Available
GeneCard ID Not Available
GenAtlas ID Not Available
HGNC ID HGNC:9197
References
General References Not Available