Identification
HMDB Protein ID CDBP05274
Secondary Accession Numbers Not Available
Name Dual specificity protein phosphatase 23
Description Not Available
Synonyms
  1. Low molecular mass dual specificity phosphatase 3
  2. VH1-like phosphatase Z
  3. LDP-3
Gene Name DUSP23
Protein Type Enzyme
Biological Properties
General Function Not Available
Specific Function Protein phosphatase that mediates dephosphorylation of proteins phosphorylated on Tyr and Ser/Thr residues. In vitro, it can dephosphorylate p44-ERK1 (MAPK3) but not p54 SAPK-beta (MAPK10) in vitro. Able to enhance activation of JNK and p38 (MAPK14).
GO Classification
Biological Process
peptidyl-tyrosine dephosphorylation
Cellular Component
cytosol
nucleus
Molecular Function
protein tyrosine/serine/threonine phosphatase activity
protein tyrosine phosphatase activity
Cellular Location Not Available
Pathways
Gene Properties
Chromosome Location 1
Locus 1q23.2
SNPs Not Available
Gene Sequence Not Available
Protein Properties
Number of Residues Not Available
Molecular Weight 16587.985
Theoretical pI 8.213
Pfam Domain Function Not Available
Signals Not Available
Transmembrane Regions Not Available
Protein Sequence
>gi|56786144|ref|NP_060293.2| dual specificity protein phosphatase 23 [Homo sapiens]
MGVQPPNFSWVLPGRLAGLALPRLPAHYQFLLDLGVRHLVSLTERGPPHSDSCPGLTLHR
LRIPDFCPPA
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID Q9BVJ7
UniProtKB/Swiss-Prot Entry Name Not Available
PDB IDs
GenBank Gene ID Not Available
GeneCard ID Not Available
GenAtlas ID Not Available
HGNC ID HGNC:21480
References
General References Not Available