Identification |
HMDB Protein ID
| CDBP05216 |
Secondary Accession Numbers
| Not Available |
Name
| Probable ATP-dependent RNA helicase DDX20 |
Description
| Not Available |
Synonyms
|
- Component of gems 3
- DEAD box protein 20
- DEAD box protein DP 103
- Gemin-3
|
Gene Name
| DDX20 |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Not Available |
Specific Function
| The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus. It may also play a role in the metabolism of snoRNPs.
|
GO Classification
|
Biological Process |
positive regulation of apoptotic process |
assembly of spliceosomal tri-snRNP |
induction of apoptosis |
ncRNA metabolic process |
negative regulation of transcription from RNA polymerase II promoter |
Cellular Component |
cytosol |
cytoskeleton |
nucleoplasm |
Cajal body |
spliceosomal complex |
transcriptional repressor complex |
Molecular Function |
ATP-dependent RNA helicase activity |
ATP binding |
DNA binding |
|
Cellular Location
|
Not Available
|
Pathways
|
Name | SMPDB/Pathwhiz | KEGG | RNA transport | Not Available | |
|
Gene Properties |
Chromosome Location
| 1 |
Locus
| 1p21.1-p13.2 |
SNPs
| Not Available |
Gene Sequence
|
Not Available
|
Protein Properties |
Number of Residues
| Not Available |
Molecular Weight
| 92239.715 |
Theoretical pI
| 6.952 |
Pfam Domain Function
|
Not Available |
Signals
|
Not Available
|
Transmembrane Regions
|
Not Available
|
Protein Sequence
|
>gi|256223453|ref|NP_009135.4| probable ATP-dependent RNA helicase DDX20 [Homo sapiens]
MAAAFEASGALAAVATAMPAEHVAVQVPAPEPTPGPVRILRTAQDLSSPRTRTGDVLLAE
PADFESLLLS
|
External Links |
GenBank ID Protein
| Not Available |
UniProtKB/Swiss-Prot ID
| Q9UHI6 |
UniProtKB/Swiss-Prot Entry Name
| Not Available |
PDB IDs
|
|
GenBank Gene ID
| Not Available |
GeneCard ID
| Not Available |
GenAtlas ID
| Not Available |
HGNC ID
| HGNC:2743 |
References |
General References
| Not Available |