Identification
HMDB Protein ID CDBP05189
Secondary Accession Numbers Not Available
Name Chromodomain-helicase-DNA-binding protein 1-like
Description Not Available
Synonyms
  1. Amplified in liver cancer protein 1
Gene Name CHD1L
Protein Type Enzyme
Biological Properties
General Function Not Available
Specific Function DNA helicase which plays a role in chromatin-remodeling following DNA damage. Targeted to sites of DNA damage through interaction with poly(ADP-ribose) and functions to regulate chromatin during DNA repair. Able to catalyze nucleosome sliding in an ATP-dependent manner. Helicase activity is strongly stimulated upon poly(ADP-ribose)-binding.
GO Classification
Biological Process
DNA repair
chromatin remodeling
Cellular Component
cytoplasm
plasma membrane
nucleus
Molecular Function
ATP binding
ATP-dependent DNA helicase activity
DNA binding
nucleotide binding
Cellular Location Not Available
Pathways
Gene Properties
Chromosome Location 1
Locus 1q12
SNPs Not Available
Gene Sequence Not Available
Protein Properties
Number of Residues Not Available
Molecular Weight 89974.62
Theoretical pI 7.02
Pfam Domain Function Not Available
Signals Not Available
Transmembrane Regions Not Available
Protein Sequence
>gi|373432615|ref|NP_001243265.1| chromodomain-helicase-DNA-binding protein 1-like isoform 2 [Homo sapiens]
MAVSWEMRWAWGRPARFAPGLSCVTYAGDKEERACLQQDLKQESRFHVLLTTYEICLKDA
SFLKSFPWSV
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID Q86WJ1
UniProtKB/Swiss-Prot Entry Name Not Available
PDB IDs Not Available
GenBank Gene ID Not Available
GeneCard ID Not Available
GenAtlas ID Not Available
HGNC ID HGNC:1916
References
General References Not Available