| Identification |
|---|
| HMDB Protein ID
| CDBP05142 |
| Secondary Accession Numbers
| Not Available |
| Name
| Lactadherin |
| Description
| Not Available |
| Synonyms
|
- Breast epithelial antigen BA46
- HMFG
- Lactadherin short form
- MFG-E8
- MFGM
- Medin
- Milk fat globule-EGF factor 8
- SED1
|
| Gene Name
| MFGE8 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in cell adhesion |
| Specific Function
| Medin is the main constituent of aortic medial amyloid |
| GO Classification
|
| Process |
| cell adhesion |
| cellular process |
|
| Cellular Location
|
- Peripheral membrane protein
- Secreted
- Membrane
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 15q25 |
| SNPs
| MFGE8 |
| Gene Sequence
|
>1164 bp
ATGCCGCGCCCCCGCCTGCTGGCCGCGCTGTGCGGCGCGCTGCTCTGCGCCCCCAGCCTC
CTCGTCGCCCTGGATATCTGTTCCAAAAACCCCTGCCACAACGGTGGTTTATGCGAGGAG
ATTTCCCAAGAAGTGCGAGGAGATGTCTTCCCCTCGTACACCTGCACGTGCCTTAAGGGC
TACGCGGGCAACCACTGTGAGACGAAATGTGTCGAGCCACTGGGCCTGGAGAATGGGAAC
ATTGCCAACTCACAGATCGCCGCCTCGTCTGTGCGTGTGACCTTCTTGGGTTTGCAGCAT
TGGGTCCCGGAGCTGGCCCGCCTGAACCGCGCAGGCATGGTCAATGCCTGGACACCCAGC
AGCAATGACGATAACCCCTGGATCCAGGTGAACCTGCTGCGGAGGATGTGGGTAACAGGT
GTGGTGACGCAGGGTGCCAGCCGCTTGGCCAGTCATGAGTACCTGAAGGCCTTCAAGGTG
GCCTACAGCCTTAATGGACACGAATTCGATTTCATCCATGATGTTAATAAAAAACACAAG
GAGTTTGTGGGTAACTGGAACAAAAACGCGGTGCATGTCAACCTGTTTGAGACCCCTGTG
GAGGCTCAGTACGTGAGATTGTACCCCACGAGCTGCCACACGGCCTGCACTCTGCGCTTT
GAGCTACTGGGCTGTGAGCTGAACGGATGCGCCAATCCCCTGGGCCTGAAGAATAACAGC
ATCCCTGACAAGCAGATCACGGCCTCCAGCAGCTACAAGACCTGGGGCTTGCATCTCTTC
AGCTGGAACCCCTCCTATGCACGGCTGGACAAGCAGGGCAACTTCAACGCCTGGGTTGCG
GGGAGCTACGGTAACGATCAGTGGCTGCAGGTGGACCTGGGCTCCTCGAAGGAGGTGACA
GGCATCATCACCCAGGGGGCCCGTAACTTTGGCTCTGTCCAGTTTGTGGCATCCTACAAG
GTTGCCTACAGTAATGACAGTGCGAACTGGACTGAGTACCAGGACCCCAGGACTGGCAGC
AGTAAGATCTTCCCTGGCAACTGGGACAACCACTCCCACAAGAAGAACTTGTTTGAGACG
CCCATCCTGGCTCGCTATGTGCGCATCCTGCCTGTAGCCTGGCACAACCGCATCGCCCTG
CGCCTGGAGCTGCTGGGCTGTTAG
|
| Protein Properties |
|---|
| Number of Residues
| 387 |
| Molecular Weight
| 43122.7 |
| Theoretical pI
| 8.21 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Lactadherin
MPRPRLLAALCGALLCAPSLLVALDICSKNPCHNGGLCEEISQEVRGDVFPSYTCTCLKG
YAGNHCETKCVEPLGMENGNIANSQIAASSVRVTFLGLQHWVPELARLNRAGMVNAWTPS
SNDDNPWIQVNLLRRMWVTGVVTQGASRLASHEYLKAFKVAYSLNGHEFDFIHDVNKKHK
EFVGNWNKNAVHVNLFETPVEAQYVRLYPTSCHTACTLRFELLGCELNGCANPLGLKNNS
IPDKQITASSSYKTWGLHLFSWNPSYARLDKQGNFNAWVAGSYGNDQWLQVDLGSSKEVT
GIITQGARNFGSVQFVASYKVAYSNDSANWTEYQDPRTGSSKIFPGNWDNHSHKKNLFET
PILARYVRILPVAWHNRIALRLELLGC
|
| External Links |
|---|
| GenBank ID Protein
| 62897029 |
| UniProtKB/Swiss-Prot ID
| Q08431 |
| UniProtKB/Swiss-Prot Entry Name
| MFGM_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AK222735 |
| GeneCard ID
| MFGE8 |
| GenAtlas ID
| MFGE8 |
| HGNC ID
| HGNC:7036 |
| References |
|---|
| General References
| Not Available |