Showing Protein Ribosomal protein S6 kinase beta-2 (CDBP05133)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 2 compounds
Identification
HMDB Protein ID CDBP05133
Secondary Accession Numbers Not Available
Name Ribosomal protein S6 kinase beta-2
Description Not Available
Synonyms
  1. 70 kDa ribosomal protein S6 kinase 2
  2. P70S6K2
  3. S6 kinase-related kinase
  4. S6K-beta
  5. S6K-beta-2
  6. S6K2
  7. SRK
  8. Serine/threonine-protein kinase 14B
  9. p70 S6 kinase beta
  10. p70 S6K-beta
  11. p70 S6KB
  12. p70 ribosomal S6 kinase beta
  13. p70-S6K 2
  14. p70-beta
Gene Name RPS6KB2
Protein Type Enzyme
Biological Properties
General Function Involved in protein serine/threonine kinase activity
Specific Function Phosphorylates specifically ribosomal protein S6
GO Classification
Function
nucleoside binding
purine nucleoside binding
adenyl nucleotide binding
adenyl ribonucleotide binding
atp binding
protein kinase activity
protein serine/threonine kinase activity
binding
catalytic activity
transferase activity
transferase activity, transferring phosphorus-containing groups
kinase activity
Process
phosphorylation
phosphorus metabolic process
phosphate metabolic process
metabolic process
biological regulation
regulation of biological process
cellular metabolic process
regulation of cellular process
signal transduction
protein amino acid phosphorylation
Cellular Location Not Available
Pathways
Gene Properties
Chromosome Location Chromosome:1
Locus 11q13.2
SNPs RPS6KB2
Gene Sequence 
>1449 bp
ATGGCGGCCGTGTTTGATTTGGATTTGGAGACGGAGGAAGGCAGCGAGGGCGAGGGCGAG
CCAGAGCTCAGCCCCGCGGACGCATGTCCCCTTGCCGAGTTGAGGGCAGCTGGCCTAGAG
CCTGTGGGACACTATGAAGAGGTGGAGCTGACTGAGACCAGCGTGAACGTTGGCCCAGAG
CGCATCGGGCCCCACTGCTTTGAGCTGCTGCGTGTGCTGGGCAAGGGGGGCTATGGCAAG
GTGTTCCAGGTGCGAAAGGTGCAAGGCACCAACTTGGGCAAAATATATGCCATGAAAGTC
CTAAGGAAGGCCAAAATTGTGCGCAATGCCAAGGACACAGCACACACACGGGCTGAGCGG
AACATTCTAGAGTCAGTGAAGCACCCCTTTATTGTGGAACTGGCCTATGCCTTCCAGACT
GGTGGCAAACTCTACCTCATCCTTGAGTGCCTCAGTGGTGGCGAGCTCTTCACGCATCTG
GAGCGAGAGGGCATCTTCCTGGAAGATACGGCCTGCTTCTACCTGGCTGAGATCACGCTG
GCCCTGGGCCATCTCCACTCCCAGGGCATCATCTACCGGGACCTCAAGCCCGAGAACATC
ATGCTCAGCAGCCAGGGCCACATCAAACTGACCGACTTTGGACTCTGCAAGGAGTCTATC
CATGAGGGCGCCGTCACTCACACCTTCTGCGGCACCATTGAGTACATGGCCCCTGAGATT
CTGGTGCGCAGTGGCCACAACCGGGCTGTGGACTGGTGGAGCCTGGGGGCCCTGATGTAC
GACATGCTCACTGGATCGCCGCCCTTCACCGCAGAGAACCGGAAGAAAACCATGGATAAG
ATCATCAGGGGCAAGCTGGCACTGCCCCCCTACCTCACCCCAGATGCCCGGGACCTTGTC
AAAAAGTTTCTGAAACGGAATCCCAGCCAGCGGATTGGGGGTGGCCCAGGGGATGCTGCT
GATGTGCAGAGACATCCCTTTTTCCGGCACATGAATTGGGACGACCTTCTGGCCTGGCGT
GTGGACCCCCCTTTCAGGCCCTGTCTGCAGTCAGAGGAGGACGTGAGCCAGTTTGATACC
CGCTTCACACGGCAGACGCCGGTGGACAGTCCTGATGACACAGCCCTCAGCGAGAGTGCC
AACCAGGCCTTCCTGGGCTTCACATACGTGGCGCCGTCTGTCCTGGACAGCATCAAGGAG
GGCTTCTCCTTCCAGCCCAAGCTGCGCTCACCCAGGCGCCTCAACAGTAGCCCCCGGGCC
CCCGTCAGCCCCCTCAAGTTCTCCCCTTTTGAGGGGTTTCGGCCCAGCCCCAGCCTGCCG
GAGCCCACGGAGCTACCTCTACCTCCACTCCTGCCACCGCCGCCGCCCTCGACCACCGCC
CCTCTCCCCATCCGTCCCCCCTCAGGGACCAAGAAGTCCAAGAGGGGCCGTGGGCGTCCA
GGGCGCTAG
Protein Properties
Number of Residues 482
Molecular Weight 53454.7
Theoretical pI 7.37
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["None"]
Protein Sequence 
>Ribosomal protein S6 kinase beta-2
MAAVFDLDLETEEGSEGEGEPELSPADACPLAELRAAGLEPVGHYEEVELTETSVNVGPE
RIGPHCFELLRVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVRNAKDTAHTRAER
NILESVKHPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLAEITL
ALGHLHSQGIIYRDLKPENIMLSSQGHIKLTDFGLCKESIHEGAVTHTFCGTIEYMAPEI
LVRSGHNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIRGKLALPPYLTPDARDLV
KKFLKRNPSQRIGGGPGDAADVQRHPFFRHMNWDDLLAWRVDPPFRPCLQSEEDVSQFDT
RFTRQTPVDSPDDTALSESANQAFLGFTYVAPSVLDSIKEGFSFQPKLRSPRRLNSSPRA
PVSPLKFSPFEGFRPSPSLPEPTELPLPPLLPPPPPSTTAPLPIRPPSGTKKSKRGRGRP
GR
GenBank ID Protein 55953117
UniProtKB/Swiss-Prot ID Q9UBS0
UniProtKB/Swiss-Prot Entry Name KS6B2_HUMAN
PDB IDs Not Available
GenBank Gene ID NM_003952.2
GeneCard ID RPS6KB2
GenAtlas ID RPS6KB2
HGNC ID HGNC:10437
References
General References Not Available