Identification
HMDB Protein ID CDBP05116
Secondary Accession Numbers Not Available
Name Cyclin-dependent kinase-like 2
Description Not Available
Synonyms
  1. Protein kinase p56 KKIAMRE
  2. Serine/threonine-protein kinase KKIAMRE
Gene Name CDKL2
Protein Type Enzyme
Biological Properties
General Function Involved in protein kinase activity
Specific Function ATP + a protein = ADP + a phosphoprotein
GO Classification
Function
transferase activity
transferase activity, transferring phosphorus-containing groups
kinase activity
nucleoside binding
purine nucleoside binding
adenyl nucleotide binding
adenyl ribonucleotide binding
atp binding
protein kinase activity
protein serine/threonine kinase activity
binding
catalytic activity
Process
phosphorus metabolic process
phosphate metabolic process
metabolic process
cellular metabolic process
protein amino acid phosphorylation
phosphorylation
Cellular Location
  1. Nucleus
  2. Cytoplasm
Pathways
Gene Properties
Chromosome Location Chromosome:4
Locus 4q21.1
SNPs CDKL2
Gene Sequence
>1482 bp
ATGGAAAAATATGAAAACCTGGGTTTGGTTGGAGAAGGGAGTTATGGAATGGTGATGAAG
TGTAGGAATAAAGATACTGGAAGAATTGTGGCCATAAAGAAGTTCTTAGAAAGTGACGAT
GACAAAATGGTTAAAAAGATTGCAATGCGAGAAATCAAGTTACTAAAGCAACTTAGGCAT
GAAAACTTGGTGAATCTCTTGGAAGTGTGTAAGAAAAAAAAACGATGGTACCTAGTCTTT
GAATTTGTTGACCACACAATTCTTGATGACTTGGAGCTCTTTCCAAATGGACTAGACTAC
CAAGTAGTTCAAAAGTATTTGTTTCAGATTATTAATGGAATTGGATTTTGTCACAGTCAC
AATATCATACACAGAGATATAAAGCCAGAGAATATATTAGTCTCCCAGTCTGGCGTTGTC
AAGCTATGCGATTTTGGATTTGCGCGAACATTGGCAGCTCCTGGGGAGGTTTATACTGAT
TATGTGGCAACCCGATGGTACAGAGCTCCAGAACTATTGGTTGGTGATGTCAAGTATGGC
AAGGCTGTTGATGTGTGGGCCATTGGTTGTCTGGTAACTGAAATGTTCATGGGGGAACCC
CTATTTCCTGGAGATTCTGATATTGATCAGCTATATCATATTATGATGTGTTTAGGTAAT
CTAATTCCAAGGCATCAGGAGCTTTTTAATAAAAATCCTGTGTTTGCTGGAGTAAGGTTG
CCTGAAATCAAGGAAAGAGAACCTCTTGAAAGACGCTATCCTAAGCTCTCTGAAGTGGTG
ATAGATTTAGCAAAGAAATGCTTACATATTGACCCCGACAAAAGACCCTTCTGTGCTGAG
CTCCTACACCATGATTTCTTTCAAATGGATGGATTTGCTGAGAGGTTTTCCCAAGAACTA
CAGTTAAAAGTACAGAAAGATGCCAGAAATGTTTCTTTATCTAAAAAATCCCAAAACAGA
AAGAAGGAAAAAGAAAAAGATGATTCCTTAGTTGAAGAAAGAAAAACACTTGTGGTACAG
GATACCAATGCTGATCCCAAAATTAAGGATTATAAACTATTTAAAATAAAAGGCTCAAAA
ATTGATGGAGAAAAAGCTGAAAAAGGCAATAGAGCTTCAAATGCCAGCTGTCTCCATGAC
AGTAGGACAAGCCACAACAAAATAGTGCCTTCAACAAGCCTCAAAGACTGCAGCAATGTC
AGCGTGGACCACACAAGGAATCCAAGCGTGGCAATTCCCCCACTTACACACAATCTTTCT
GCAGTTGCTCCCAGCATTAATTCTGGAATGGGGACTGAGACTATACCAATTCAGGGTTAC
AGAGTGGATGAGAAAACTAAGAAGTGTTCTATTCCATTTGTTAAACCGAACAGACATTCC
CCATCAGGCATTTATAACATTAATGTGACCACATTAGTATCAGGACCTCCCCTGTCAGAT
GATTCAGGGGCTGATTTGCCTCAAATGGAACACCAGCACTGA
Protein Properties
Number of Residues 493
Molecular Weight 56018.1
Theoretical pI 8.34
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["None"]
Protein Sequence
>Cyclin-dependent kinase-like 2
MEKYENLGLVGEGSYGMVMKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRH
ENLVNLLEVCKKKKRWYLVFEFVDHTILDDLELFPNGLDYQVVQKYLFQIINGIGFCHSH
NIIHRDIKPENILVSQSGVVKLCDFGFARTLAAPGEVYTDYVATRWYRAPELLVGDVKYG
KAVDVWAIGCLVTEMFMGEPLFPGDSDIDQLYHIMMCLGNLIPRHQELFNKNPVFAGVRL
PEIKEREPLERRYPKLSEVVIDLAKKCLHIDPDKRPFCAELLHHDFFQMDGFAERFSQEL
QLKVQKDARNVSLSKKSQNRKKEKEKDDSLVEERKTLVVQDTNADPKIKDYKLFKIKGSK
IDGEKAEKGNRASNASCLHDSRTSHNKIVPSTSLKDCSNVSVDHTRNPSVAIPPLTHNLS
AVAPSINSGMGTETIPIQGYRVDEKTKKCSIPFVKPNRHSPSGIYNINVTTLVSGPPLSD
DSGADLPQMEHQH
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID Q92772
UniProtKB/Swiss-Prot Entry Name CDKL2_HUMAN
PDB IDs Not Available
GenBank Gene ID U35146
GeneCard ID CDKL2
GenAtlas ID CDKL2
HGNC ID HGNC:1782
References
General References Not Available