| Identification |
|---|
| HMDB Protein ID
| CDBP05108 |
| Secondary Accession Numbers
| Not Available |
| Name
| Carboxypeptidase N subunit 2 |
| Description
| Not Available |
| Synonyms
|
- Carboxypeptidase N 83 kDa chain
- Carboxypeptidase N large subunit
- Carboxypeptidase N polypeptide 2
- Carboxypeptidase N regulatory subunit
|
| Gene Name
| CPN2 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in protein binding |
| Specific Function
| The 83 kDa subunit binds and stabilizes the catalytic subunit at 37 degrees Celsius and keeps it in circulation. Under some circumstances it may be an allosteric modifier of the catalytic subunit |
| GO Classification
|
| Function |
| binding |
| protein binding |
|
| Cellular Location
|
- Secreted
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:3 |
| Locus
| 3q29 |
| SNPs
| CPN2 |
| Gene Sequence
|
>1638 bp
ATGCTCCCTGGAGCCTGGCTGCTCTGGACCTCCCTCCTGCTCCTGGCCAGGCCTGCCCAG
CCCTGTCCCATGGGTTGTGACTGCTTCGTCCAGGAGGTGTTCTGCTCAGATGAGGAGCTT
GCCACCGTCCCGCTGGACATCCCGCCATATACGAAAAACATCATCTTTGTGGAGACCTCG
TTCACCACATTGGAAACCAGAGCTTTTGGCAGTAACCCCAACTTGACCAAGGTGGTCTTC
CTCAACACTCAGCTCTGCCAGTTTAGGCCGGATGCCTTTGGGGGGCTGCCCAGGCTGGAG
GACCTGGAGGTCACAGGCAGTAGCTTCTTGAACCTCAGCACCAACATCTTCTCCAACCTG
ACCTCGCTGGGCAAGCTCACCCTCAACTTCAACATGCTGGAGGCTCTGCCCGAGGGTCTT
TTCCAGCACCTGGCTGCCCTGGAGTCCCTCCACCTGCAGGGGAACCAGCTCCAGGCCCTG
CCCAGGAGGCTCTTCCAGCCTCTGACCCATCTGAAGACACTCAACCTGGCCCAGAACCTC
CTGGCCCAGCTCCCGGAGGAGCTGTTCCACCCACTCACCAGCCTGCAGACCCTGAAGCTG
AGCAACAACGCGCTCTCTGGTCTCCCCCAGGGTGTGTTTGGCAAACTGGGCAGCCTGCAG
GAGCTCTTCCTGGACAGCAACAACATCTCGGAGCTGCCCCCTCAGGTGTTCTCCCAGCTC
TTCTGCCTAGAGAGGCTGTGGCTGCAACGCAACGCCATCACGCACCTGCCGCTCTCCATC
TTTGCCTCCCTGGGTAATCTGACCTTTCTGAGCTTGCAGTGGAACATGCTTCGGGTCCTG
CCTGCCGGCCTCTTTGCCCACACCCCATGCCTGGTTGGCCTGTCTCTGACCCATAACCAG
CTGGAGACTGTCGCTGAGGGCACCTTTGCCCACCTGTCCAACCTGCGTTCCCTCATGCTC
TCATACAATGCCATTACCCACCTCCCAGCTGGCATCTTCAGAGACCTGGAGGAGTTGGTC
AAACTCTACCTGGGCAGCAACAACCTTACGGCGCTGCACCCAGCCCTCTTCCAGAACCTG
TCCAAGCTGGAGCTGCTCAGCCTCTCCAAGAACCAGCTGACCACACTTCCGGAGGGCATC
TTCGACACCAACTACAACCTGTTCAACCTGGCCCTGCACGGTAACCCCTGGCAGTGCGAC
TGCCACCTGGCCTACCTCTTCAACTGGCTGCAGCAGTACACCGATCGGCTCCTGAACATC
CAGACCTACTGCGCTGGCCCTGCCTACCTCAAAGGCCAGGTGGTGCCCGCCTTGAATGAG
AAGCAGCTGGTGTGTCCCGTCACCCGGGACCACTTGGGCTTCCAGGTCACGTGGCCGGAC
GAAAGCAAGGCAGGGGGCAGCTGGGATCTGGCTGTGCAGGAAAGGGCAGCCCGGAGCCAG
TGCACCTACAGCAACCCCGAGGGCACCGTGGTGCTCGCCTGTGACCAGGCCCAGTGTCGC
TGGCTGAACGTCCAGCTCTCTCCTCGGCAGGGCTCCCTGGGACTGCAGTACAATGCTAGT
CAGGAGTGGGACCTGAGGTCGAGCTGCGGTTCTCTGCGGCTCACCATGTCTATCGAGGCT
CGGGCAGCAGGGCCCTAG
|
| Protein Properties |
|---|
| Number of Residues
| 545 |
| Molecular Weight
| 60614.1 |
| Theoretical pI
| 5.89 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Carboxypeptidase N subunit 2
MLPGAWLLWTSLLLLARPAQPCPMGCDCFVQEVFCSDEELATVPLDIPPYTKNIIFVETS
FTTLETRAFGSNPNLTKVVFLNTQLCQFRPDAFGGLPRLEDLEVTGSSFLNLSTNIFSNL
TSLGKLTLNFNMLEALPEGLFQHLAALESLHLQGNQLQALPRRLFQPLTHLKTLNLAQNL
LAQLPEELFHPLTSLQTLKLSNNALSGLPQGVFGKLGSLQELFLDSNNISELPPQVFSQL
FCLERLWLQRNAITHLPLSIFASLGNLTFLSLQWNMLRVLPAGLFAHTPCLVGLSLTHNQ
LETVAEGTFAHLSNLRSLMLSYNAITHLPAGIFRDLEELVKLYLGSNNLTALHPALFQNL
SKLELLSLSKNQLTTLPEGIFDTNYNLFNLALHGNPWQCDCHLAYLFNWLQQYTDRLLNI
QTYCAGPAYLKGQVVPALNEKQLVCPVTRDHLGFQVTWPDESKAGGSWDLAVQERAARSQ
CTYSNPEGTVVLACDQAQCRWLNVQLSPWQGSLGLQYNASQEWDLRSSCGSLRLTVSIEA
RAAGP
|
| External Links |
|---|
| GenBank ID Protein
| 51173528 |
| UniProtKB/Swiss-Prot ID
| P22792 |
| UniProtKB/Swiss-Prot Entry Name
| CPN2_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| J05158 |
| GeneCard ID
| CPN2 |
| GenAtlas ID
| CPN2 |
| HGNC ID
| HGNC:2313 |
| References |
|---|
| General References
| Not Available |