Cannabis Compound Database: Showing Protein Glycerophosphoinositol inositolphosphodiesterase GDPD2 (CDBP05102)

Identification Biological properties Gene properties Protein properties External links References XML Show 1 compounds

Identification

HMDB Protein ID

CDBP05102

Secondary Accession Numbers

Not Available

Name

Glycerophosphoinositol inositolphosphodiesterase GDPD2

Description

Not Available

Synonyms

Glycerophosphodiester phosphodiesterase 3
Glycerophosphodiester phosphodiesterase domain-containing protein 2
Osteoblast differentiation promoting factor

Gene Name

GDPD2

Protein Type

Enzyme

Biological Properties

General Function

Involved in glycerophosphodiester phosphodiesterase activity

Specific Function

Has glycerophosphoinositol inositolphosphodiesterase activity and specifically hydrolyzes glycerophosphoinositol, with no activity for other substrates such as glycerophosphoinositol 4-phosphate, glycerophosphocholine, glycerophosphoethanolamine, and glycerophosphoserine. Accelerates the program of osteoblast differentiation and growth. May play a role in remodeling of the actin cytoskeleton (By similarity).

GO Classification

Biological Process
lipid metabolic process
glycerol metabolic process
Cellular Component
cytoskeleton
cytoplasm
plasma membrane
integral to membrane
Function
glycerophosphodiester phosphodiesterase activity
hydrolase activity, acting on ester bonds
catalytic activity
hydrolase activity
phosphoric ester hydrolase activity
phosphoric diester hydrolase activity
Molecular Function
metal ion binding
glycerophosphodiester phosphodiesterase activity
glycerophosphoinositol inositolphosphodiesterase activity
Process
small molecule metabolic process
alcohol metabolic process
polyol metabolic process
alditol metabolic process
glycerol metabolic process
lipid metabolic process
metabolic process
primary metabolic process

Cellular Location

Cell membrane
Cytoplasm
Cytoplasm
Multi-pass membrane protein
cytoskeleton

Pathways

Not Available

Gene Properties

Chromosome Location

Locus

Xq13.1

SNPs

GDPD2

Gene Sequence

>1620 bp
ATGGCCGAGTCCCCCGGCTGCTGCTCCGTCTGGGCCCGCTGCCTCCACTGCCTGTATAGC
TGCCACTGGAGGAAATGCCCCAGAGAGAGGATGCAAACCAGCAAGTGCGACTGTATCTGG
TTTGGCCTGCTCTTCCTCACCTTCCTCCTTTCCCTGAGCTGGCTGTACATCGGGCTCGTC
CTTCTCAATGACCTGCACAACTTCAATGAATTCCTCTTCCGCCGCTGGGGACACTGGATG
GACTGGTCCCTGGCATTCCTGCTGGTCATCTCTCTACTGGTCACATATGCATCCTTGCTA
TTGGTCCTGGCCCTGCTCCTGCGGCTTTGTAGACAGCCCCTGCATCTGCACAGCCTCCAC
AAGGTGCTGCTGCTCCTCATTATGCTGCTTGTGGCGGCTGGCCTTGTGGGACTGGACATC
CAATGGCAGCAGGAGTGGCATAGCTTGCGTGTGTCACTGCAGGCCACAGCCCCATTCCTT
CATATTGGAGCAGCCGCTGGAATTGCCCTCCTGGCCTGGCCTGTGGCTGATACCTTCTAC
CGTATCCACCGAAGAGGTCCCAAGATTCTGCTACTGCTCCTATTTTTTGGAGTTGTCCTG
GTCATCTACTTGGCCCCCCTATGCATCTCCTCACCCTGCATCATGGAACCCAGAGACTTA
CCACCCAAGCCTGGGCTGGTGGGACACCGAGGGGCCCCCATGCTGGCTCCCGAGAACACC
CTGATGTCCTTGCGGAAGACAGCTGAATGCGGAGCTACTGTGTTTGAGACTGATGTGATG
GTCAGCTCCGATGGGGTCCCCTTCCTCATGCATGATGAGCACCTCAGCAGGACCACGAAT
GTAGCCTCTGTATTCCCAACCCGAATCACAGCCCACAGCAGTGACTTCTCCTGGACTGAA
CTGAAGAGACTCAATGCTGGATCCTGGTTCCTAGAGAGGCGACCCTTCTGGGGGGCCAAA
CCGCTGGCAGGCCCTGATCAGAAAGAGGCTGAGAGTCAGACGGTACCAGCATTAGAAGAG
CTATTGGAGGAAGCTGCAGCCCTCAACCTTTCCATCATGTTCGACTTGCGCCGACCCCCA
CAGAACCACACATACTATGACACTTTTGTGATCCAGACATTGGAGACTGTGCTGAATGCA
AGGGTGCCCCAAGCCATGGTCTTTTGGCTACCAGATGAAGATCGGGCTAATGTCCAACGA
CGGGCACCTGGAATGCGCCAGATATATGGACGTCAGGGAGGCAACAGAACGGAGAGGCCC
CAGTTTCTTAACCTCCCCTATCAAGATCTGCCACTATTGGATATCAAGGCATTGCATAAG
GATAATGTCTCGGTGAACCTATTTGTAGTGAACAAGCCCTGGCTCTTCTCTCTGCTTTGG
TGTGCAGGGGTGGATTCGGTCACCACCAACGACTGCCAGCTGCTGCAGCAGATGCGTTAC
CCTATCTGGCTTATTACCCCTCAAACCTACCTAATCATATGGGTCATTACCAATTGTGTT
TCCACCATGCTGCTTTTGTGGACCTTCCTCCTCCAAAGGAGATTTGTTAAGAAGAGAGGG
AAAACTGGCTTAGAAACAGCAGTGCTGCTGACAAGGATCAACAATTTCATGATGGAGTGA

Protein Properties

Number of Residues

539

Molecular Weight

52185.905

Theoretical pI

8.528

Pfam Domain Function

GDPD (PF03009 )

Signals

Not Available

Transmembrane Regions

Not Available

Protein Sequence

>Glycerophosphoinositol inositolphosphodiesterase GDPD2
MAESPGCCSVWARCLHCLYSCHWRKCPRERMQTSKCDCIWFGLLFLTFLLSLSWLYIGLV
LLNDLHNFNEFLFRRWGHWMDWSLAFLLVISLLVTYASLLLVLALLLRLCRQPLHLHSLH
KVLLLLIMLLVAAGLVGLDIQWQQEWHSLRVSLQATAPFLHIGAAAGIALLAWPVADTFY
RIHRRGPKILLLLLFFGVVLVIYLAPLCISSPCIMEPRDLPPKPGLVGHRGAPMLAPENT
LMSLRKTAECGATVFETDVMVSSDGVPFLMHDEHLSRTTNVASVFPTRITAHSSDFSWTE
LKRLNAGSWFLERRPFWGAKPLAGPDQKEAESQTVPALEELLEEAAALNLSIMFDLRRPP
QNHTYYDTFVIQTLETVLNARVPQAMVFWLPDEDRANVQRRAPGMRQIYGRQGGNRTERP
QFLNLPYQDLPLLDIKALHKDNVSVNLFVVNKPWLFSLLWCAGVDSVTTNDCQLLQQMRY
PIWLITPQTYLIIWVITNCVSTMLLLWTFLLQRRFVKKRGKTGLETAVLLTRINNFMME

External Links

GenBank ID Protein

10039439

UniProtKB/Swiss-Prot ID

Q9HCC8

UniProtKB/Swiss-Prot Entry Name

GDPD2_HUMAN

PDB IDs

Not Available

GenBank Gene ID

AB048363

GeneCard ID