Showing Protein Rho guanine nucleotide exchange factor 17 (CDBP05090)
| Identification | ||||||||||||||||||||
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| HMDB Protein ID | CDBP05090 | |||||||||||||||||||
| Secondary Accession Numbers | Not Available | |||||||||||||||||||
| Name | Rho guanine nucleotide exchange factor 17 | |||||||||||||||||||
| Description | Not Available | |||||||||||||||||||
| Synonyms |
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| Gene Name | ARHGEF17 | |||||||||||||||||||
| Protein Type | Enzyme | |||||||||||||||||||
| Biological Properties | ||||||||||||||||||||
| General Function | Involved in Rho guanyl-nucleotide exchange factor activity | |||||||||||||||||||
| Specific Function | Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPases | |||||||||||||||||||
| GO Classification |
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| Cellular Location | Not Available | |||||||||||||||||||
| Pathways | Not Available | |||||||||||||||||||
| Gene Properties | ||||||||||||||||||||
| Chromosome Location | Chromosome:1 | |||||||||||||||||||
| Locus | 11q13.4 | |||||||||||||||||||
| SNPs | ARHGEF17 | |||||||||||||||||||
| Gene Sequence |
>6192 bp ATGGCGGACGGGGCACCCCGGCCCCAGCTTTACCGCAGCGTCTCGTTCAAGCTGCTGGAG CGCTGGAGCGGCGGCCCCGGGCTGAGGGAGGAGGACACGGACACCCCCGGCTTGAGGCGA CGCGCCTCGTGCCGGCCGACCACGGCTGCCCGGGGCCAGCCCTCTCGGCGCGTGTCCAAG CTGGCGTCTGGGCCCCTGGCCGCCCCCGCGCAGCCGCGCCCGCTCCGCAGCCTCTCGCCG TCGGTTCGCCAGCTCTCCCGGCGCTTCGACGCGCCGCGTCTGGACGACGGCTCCGCTGGG ACCCGAGACGGAGGCGTCTTACCCGCGGCCGCGGAAGAAGCGGCCGAGGGCCCAGCGCGA GGAGCCTGGCCCAGCGTCACCGAGATGCGCAAGCTCTTCGGCGGTCCTGGCTCCAGGAGG CCCAGCGCCGACTCTGAATCCCCAGGAACGCCCAGCCCCGACGGTGCCGCGTGGGAGCCT CCGGCTCGGGAGTCGCGGCAGCCACCGACGCCACCCCCTCGGACATGCTTCCCCCTGGCG GGTCTGCGTTCGGCGCGGCCCCTGACCGGGCCGGAGACCGAAGGGAGGCTGCGCCGGCCG CAGCAGCAACAGGAGCGGGCGCAGCGTCCAGCGGATGGTTTACATTCTTGGCATATCTTC TCCCAACCGCAGGCCGGGGCCCGGGCCTCCTGCTCCTCCTCCTCCATCGCCGCCTCCTAT CCTGTCAGCCGCAGTCGTGCTGCCAGCTCCAGCGAGGAGGAAGAGGAGGGCCCGCCGCAG CTGCCTGGAGCCCAGAGTCCGGCCTACCACGGCGGCCACTCCTCGGGCAGTGACGACGAC CGAGACGGTGAGGGCGGCCACCGCTGGGGAGGGAGGCCCGGGCTCAGGCCTGGAAGCTCC CTATTGGATCAGGACTGCAGGCCTGACAGTGATGGGTTAAATCTAAGCAGCATGAACTCA GCAGGGGTTTCTGGGAGCCCTGAGCCCCCAACATCTCCAAGAGCCCCTAGAGAAGAAGGA CTCCGGGAGTGGGGTAGTGGCTCTCCGCCCTGCGTCCCAGGTCCCCAGGAGGGACTTCGG CCTATGTCTGACTCTGTGGGAGGAGCTTTCCGTGTGGCCAAGGTGAGCTTTCCCTCGTAC CTGGCCAGCCCCGCAGGCTCCCGCGGTAGCAGCCGTTATTCCAGCACGGAGACCCTCAAG GACGACGACCTATGGTCTAGTAGGGGTTCTGGGGGCTGGGGCGTGTACCGCTCCCCTAGC TTTGGAGCTGGGGAAGGGCTCCTGCGGTCCCAGGCTCGAACCCGTGCCAAAGGACCTGGA GGCACCTCTAGGGCATTGAGGGATGGAGGATTTGAGCCTGAAAAGAGTCGACAGCGGAAG TCCCTGTCAAATCCAGATATCGCCTCAGAGACCCTGACGCTTCTCAGTTTCCTGCGCTCA GACCTTTCAGAGCTGAGGGTCCGAAAACCTGGTGGGAGCTCCGGGGACCGTGGAAGCAAC CCCCTAGATGGCAGAGACTCACCATCCGCAGGTGGCCCTGTGGGGCAACTTGAACCCATA CCCATCCCAGCCCCAGCATCACCTGGCACGCGCCCCACACTCAAGGACTTGACAGCCACT CTGCGGAGAGCAAAGTCATTCACCTGCTCTGAGAAGCCCATGGCCCGCCGCCTGCCCCGC ACCAGTGCTCTGAAGTCCAGCTCCTCCGAGCTCCTGCTCACAGGCCCTGGTGCCGAGGAG GATCCGCTGCCCCTCATCGTCCAGGACCAATATGTGCAGGAGGCCCGCCAGGTTTTTGAG AAGATCCAGCGCATGGGTGCCCAACAAGATGATGGAAGCGATGCCCCCCCTGGAAGCCCT GACTGGGCAGGGGATGTGACCCGAGGGCAGCGGTCCCAGGAGGAGCTCTCAGGCCCTGAG TCCAGTCTGACAGATGAAGGCATTGGGGCAGACCCTGAGCCTCCTGTTGCAGCATTTTGC GGCCTGGGTACCACAGGGATGTGGCGACCTCTTTCCTCATCCTCGGCCCAGACGAACCAC CATGGCCCTGGGACTGAGGACAGTCTGGGCGGGTGGGCCCTGGTGTCGCCTGAGACCCCT CCCACACCAGGTGCCCTCCGCCGACGACGCAAAGTCCCACCTTCAGGTTCTGGTGGGAGC GAATTGAGCAATGGGGAGGCAGGGGAGGCCTACAGGTCCCTGAGTGACCCAATTCCTCAG CGCCACCGGGCTGCCACCTCTGAAGAGCCTACTGGGTTCTCTGTGGACAGCAACCTCCTG GGCTCACTGAGCCCCAAGACAGGGCTCCCTGCCACCTCAGCCATGGATGAGGGCTTGACC AGTGGTCACAGTGACTGGTCTGTGGGCAGTGAAGAGAGCAAGGGATATCAGGAGGTTATT CAGAGCATAGTTCAGGGGCCTGGCACCCTGGGGCGTGTGGTGGACGACAGGATTGCTGGC AAAGCCCCCAAGAAGAAATCCCTGAGTGACCCCAGCCGCCGTGGGGAGCTGGCTGGGCCT GGATTCGAGGGCCCTGGAGGGGAGCCCATCCGAGAAGTTGAGCCCATGCTGCCTCCATCC AGCAGCGAGCCCATCCTTGTAGAGCAGCGGGCAGAGCCAGAAGAACCTGGTGCCACCAGG AGCCGGGCACAGTCTGAAAGGGCCCTACCTGAGGCTCTGCCTCCCCCTGCCACTGCCCAC CGAAACTTTCACCTTGACCCCAAGCTGGCTGACATTCTGTCCCCGAGGCTAATCCGCCGA GGCTCCAAGAAGCGCCCAGCTCGGAGTAGTCACCAGGAGCTTCGGAGAGACGAGGGCAGT CAGGACCAGACTGGCAGCCTGTCTCGGGCCCGGCCCTCCTCCAGACACGTTCGCCATGCC AGTGTGCCCGCCACATTTATGCCTATTGTGGTGCCTGAGCCACCAACTTCTGTTGGTCCC CCTGTGGCTGTGCCAGAACCCATAGGCTTCCCTACCCGAGCCCATCCCACGTTGCAGGCA CCATCGCTCGAGGACGTCACCAAGCAGTACATGCTGAACCTGCACTCCGGTGAGGTCCCT GCCCCAGTGCCAGTGGACATGCCCTGCTTGCCTCTGGCTGCACCGCCCTCTGCTGAGGCC AAGCCCCCTGAGGCAGCTCGGCCTGCAGATGAGCCTACCCCTGCCAGCAAGTGCTGCAGC AAGCCACAGGTGGACATGCGGAAGCACGTGGCCATGACCCTGCTGGACACAGAGCAGTCG TATGTGGAGTCGCTGCGCACCCTGATGCAGGGCTACATGCAGCCGCTGAAGCAGCCAGAG AACTCCGTGCTCTGTGACCCTTCACTGGTGGACGAGATCTTCGACCAGATCCCCGAGCTC CTGGAGCACCACGAGCAATTCCTGGAGCAGGTTCGGCACTGCATGCAGACCTGGCATGCC CAGCAGAAGGTGGGAGCCCTGCTCGTCCAGTCGTTCTCCAAGGATGTCCTAGTAAACATC TATTCTGCCTATATCGATAACTTCCTCAATGCAAAGGATGCTGTGCGTGTGGCCAAGGAG GCGAGGCCTGCCTTTCTCAAGTTCCTAGAGCAAAGCATGCGTGAGAACAAGGAGAAGCAG GCGCTGTCTGACCTCATGATCAAGCCTGTGCAGCGGATCCCACGCTACGAGCTTCTGGTG AAGGACCTCCTGAAGCATACACCTGAGGACCACCCGGACCATCCACTCCTGCTGGAGGCG CAGCGGAACATCAAGCAGGTGGCTGAGCGCATCAACAAGGGTGTGCGGAGTGCCGAGGAG GCGGAGCGCCATGCCCGTGTGCTGCAGGAGATAGAGGCTCACATCGAGGGCATGGAGGAT CTCCAGGCCCCTCTGCGGCGGTTCCTGAGACAGGAGATGGTCATTGAAGTGAAGGCGATC GGTGGCAAGAAGGACCGGTCTCTCTTCCTGTTCACGGACCTCATCGTCTGCACCACTCTG AAGCGAAAGTCAGGCTCCCTGCGGCGCAGCTCCATGAGCCTGTACACGGCAGCCAGTGTC ATTGACACAGCCAGCAAGTACAAGATGCTGTGGAAGCTGCCGCTGGAAGACGCAGACATC ATCAAAGGGGCATCCCAAGCCACCAATCGGGAGAACATCCAGAAGGCCATCAGCCGCCTT GATGAGGACCTCACCACCCTGGGCCAAATGAGCAAGCTCTCTGAGAGCCTTGGTTTCCCC CACCAGAGCCTGGACGATGCACTGCGGGACCTCTCAGCTGCCATGCACCGGGACCTGTCG GAGAAGCAGGCGCTGTGCTACGCGCTTTCCTTCCCGCCAACCAAGCTGGAGCTGTGCGCC ACTCGGCCCGAGGGCACCGACTCCTACATTTTTGAGTTCCCTCACCCTGACGCCCGCCTT GGTTTTGAACAGGCCTTCGATGAGGCCAAGAGGAAGCTGGCATCCAGCAAAAGCTGTCTA GACCCTGAGTTCCTGAAGGCCATCCCCATCATGAAAACCCGCAGTGGCATGCAGTTCTCC TGTGCGGCTCCCACCCTGAACAGCTGCCCGGAGCCCTCGCCTGAGGTATGGGTCTGCAAC AGCGACGGCTACGTGGGCCAGGTGTGCCTGCTGAGCCTGCGCGCCGAGCCGGACGTGGAG GCCTGCATCGCCGTCTGTTCCGCCCGCATCCTCTGCATCGGGGCGGTGCCCGGGCTGCAG CCTCGCTGCCACCGGGAGCCTCCTCCGTCGCTGAGGAGTCCTCCAGAGACGGCACCGGAG CCCGCCGGGCCGGAGCTGGACGTCGAGGCCGCTGCAGACGAGGAAGCCGCGACGCTCGCG GAGCCGGGGCCGCAGCCCTGCCTTCACATCTCCATTGCAGGCTCGGGCTTGGAGATGACG CCGGGCCTCGGCGAGGGTGACCCCCGCCCAGAGCTGGTGCCCTTTGACAGTGACTCTGAC GATGAGTCTTCGCCCAGCCCCTCGGGGACGCTGCAGAGCCAGGCCAGCCGGTCCACCATC TCCTCCAGCTTTGGCAATGAGGAGACCCCGAGTTCCAAGGAGGCCACGGCAGAGACCACC AGCTCAGAGGAGGAGCAGGAGCCAGGCTTCCTGCCACTGTCTGGCTCCTTTGGGCCTGGT GGTCCCTGCGGCACCAGCCCAATGGATGGGAGAGCCCTTCGCCGCTCCAGCCACGGCTCC TTCACCCGGGGCAGCCTTGAGGACCTGCTGAGTGTCGACCCTGAGGCCTACCAGAGCTCC GTGTGGCTGGGCACTGAGGATGGCTGTGTCCACGTGTACCAGTCCTCCGACAGCATCCGT GACCGCAGGAACAGCATGAAGCTCCAGCATGCGGCCTCTGTGACCTGCATCTTGTATCTG AATAACCAGGTGTTTGTGTCTCTGGCCAATGGAGAGCTTGTGGTCTACCAAAGGGAAGCA GGCCATTTCTGGGACCCCCAGAACTTCAAATCAGTGACCTTGGGCACCCAGGGGAGCCCC ATCACCAAGATGGTATCTGTGGGTGGGCGGCTGTGGTGTGGCTGCCAGAACCGAGTCCTT GTCCTGAGCCCTGACACGCTGCAGCTGGAGCACATGTTTTACGTGGGTCAGGATTCAAGC CGCTGCGTGGCTTGCATGGTGGACTCCAGCCTGGGTGTGTGGGTGACATTGAAAGGTAGT GCCCACGTGTGTCTCTACCATCCAGACACCTTTGAGCAGCTGGCAGAAGTAGACGTCACT CCTCCCGTGCACAGGATGCTGGCAGGCTCGGATGCCATCATCCGGCAGCACAAGGCTGCC TGTCTGCGAATCACAGCGCTGCTGGTGTGTGAGGAGCTGCTGTGGGTGGGCACCAGTGCT GGTGTCGTCCTCACCATGCCCACTTCGCCCGGTACTGTCAGCTGCCCACGGGCACCACTC AGTCCCACAGGCCTCGGCCAGGGACACACCGGCCACGTCCGCTTCTTGGCTGCAGTCCAG CTGCCAGATGGCTTCAACCTGCTCTGCCCAACCCCACCACCTCCCCCAGACACAGGCCCC GAGAAGCTGCCATCACTGGAGCACCGGGACTCCCCTTGGCACCGAGGCCCCGCCCCTGCC AGGCCTAAAATGCTGGTTATCAGTGGAGGTGATGGCTATGAGGACTTCCGACTCAGCAGT GGGGGCGGCAGCAGCAGTGAGACTGTGGGTCGAGACGACAGCACAAACCACCTCCTCCTG TGGAGGGTGTGA |
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| Protein Properties | ||||||||||||||||||||
| Number of Residues | 2063 | |||||||||||||||||||
| Molecular Weight | 221670.1 | |||||||||||||||||||
| Theoretical pI | 6.22 | |||||||||||||||||||
| Pfam Domain Function |
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| Signals |
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| Transmembrane Regions |
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| Protein Sequence |
>Rho guanine nucleotide exchange factor 17 MADGAPRPQLYRSVSFKLLERWSGGPGLREEDTDTPGLRRRASCRPTTAARGQPSRRVSK LASGPLAAPAQPRPLRSLSPSVRQLSRRFDAPRLDDGSAGTRDGGVLPAAAEEAAEGPAR GAWPSVTEMRKLFGGPGSRRPSADSESPGTPSPDGAAWEPPARESRQPPTPPPRTCFPLA GLRSARPLTGPETEGRLRRPQQQQERAQRPADGLHSWHIFSQPQAGARASCSSSSIAASY PVSRSRAASSSEEEEEGPPQLPGAQSPAYHGGHSSGSDDDRDGEGGHRWGGRPGLRPGSS LLDQDCRPDSDGLNLSSMNSAGVSGSPEPPTSPRAPREEGLREWGSGSPPCVPGPQEGLR PMSDSVGGAFRVAKVSFPSYLASPAGSRGSSRYSSTETLKDDDLWSSRGSGGWGVYRSPS FGAGEGLLRSQARTRAKGPGGTSRALRDGGFEPEKSRQRKSLSNPDIASETLTLLSFLRS DLSELRVRKPGGSSGDRGSNPLDGRDSPSAGGPVGQLEPIPIPAPASPGTRPTLKDLTAT LRRAKSFTCSEKPMARRLPRTSALKSSSSELLLTGPGAEEDPLPLIVQDQYVQEARQVFE KIQRMGAQQDDGSDAPPGSPDWAGDVTRGQRSQEELSGPESSLTDEGIGADPEPPVAAFC GLGTTGMWRPLSSSSAQTNHHGPGTEDSLGGWALVSPETPPTPGALRRRRKVPPSGSGGS ELSNGEAGEAYRSLSDPIPQRHRAATSEEPTGFSVDSNLLGSLSPKTGLPATSAMDEGLT SGHSDWSVGSEESKGYQEVIQSIVQGPGTLGRVVDDRIAGKAPKKKSLSDPSRRGELAGP GFEGPGGEPIREVEPMLPPSSSEPILVEQRAEPEEPGATRSRAQSERALPEALPPPATAH RNFHLDPKLADILSPRLIRRGSKKRPARSSHQELRRDEGSQDQTGSLSRARPSSRHVRHA SVPATFMPIVVPEPPTSVGPPVAVPEPIGFPTRAHPTLQAPSLEDVTKQYMLNLHSGEVP APVPVDMPCLPLAAPPSAEAKPPEAARPADEPTPASKCCSKPQVDMRKHVAMTLLDTEQS YVESLRTLMQGYMQPLKQPENSVLCDPSLVDEIFDQIPELLEHHEQFLEQVRHCMQTWHA QQKVGALLVQSFSKDVLVNIYSAYIDNFLNAKDAVRVAKEARPAFLKFLEQSMRENKEKQ ALSDLMIKPVQRIPRYELLVKDLLKHTPEDHPDHPLLLEAQRNIKQVAERINKGVRSAEE AERHARVLQEIEAHIEGMEDLQAPLRRFLRQEMVIEVKAIGGKKDRSLFLFTDLIVCTTL KRKSGSLRRSSMSLYTAASVIDTASKYKMLWKLPLEDADIIKGASQATNRENIQKAISRL DEDLTTLGQMSKLSESLGFPHQSLDDALRDLSAAMHRDLSEKQALCYALSFPPTKLELCA TRPEGTDSYIFEFPHPDARLGFEQAFDEAKRKLASSKSCLDPEFLKAIPIMKTRSGMQFS CAAPTLNSCPEPSPEVWVCNSDGYVGQVCLLSLRAEPDVEACIAVCSARILCIGAVPGLQ PRCHREPPPSLRSPPETAPEPAGPELDVEAAADEEAATLAEPGPQPCLHISIAGSGLEMT PGLGEGDPRPELVPFDSDSDDESSPSPSGTLQSQASRSTISSSFGNEETPSSKEATAETT SSEEEQEPGFLPLSGSFGPGGPCGTSPMDGRALRRSSHGSFTRGSLEDLLSVDPEAYQSS VWLGTEDGCVHVYQSSDSIRDRRNSMKLQHAASVTCILYLNNQVFVSLANGELVVYQREA GHFWDPQNFKSVTLGTQGSPITKMVSVGGRLWCGCQNRVLVLSPDTLQLEHMFYVGQDSS RCVACMVDSSLGVWVTLKGSAHVCLYHPDTFEQLAEVDVTPPVHRMLAGSDAIIRQHKAA CLRITALLVCEELLWVGTSAGVVLTMPTSPGTVSCPRAPLSPTGLGQGHTGHVRFLAAVQ LPDGFNLLCPTPPPPPDTGPEKLPSLEHRDSPWHRGPAPARPKMLVISGGDGYEDFRLSS GGGSSSETVGRDDSTNHLLLWRV |
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| External Links | ||||||||||||||||||||
| GenBank ID Protein | 21361458 | |||||||||||||||||||
| UniProtKB/Swiss-Prot ID | Q96PE2 | |||||||||||||||||||
| UniProtKB/Swiss-Prot Entry Name | ARHGH_HUMAN | |||||||||||||||||||
| PDB IDs | Not Available | |||||||||||||||||||
| GenBank Gene ID | NM_014786.3 | |||||||||||||||||||
| GeneCard ID | ARHGEF17 | |||||||||||||||||||
| GenAtlas ID | ARHGEF17 | |||||||||||||||||||
| HGNC ID | HGNC:21726 | |||||||||||||||||||
| References | ||||||||||||||||||||
| General References | Not Available | |||||||||||||||||||