Showing Protein IQ motif and SEC7 domain-containing protein 3 (CDBP05088)
| Identification | |||||||||||||||||||
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| HMDB Protein ID | CDBP05088 | ||||||||||||||||||
| Secondary Accession Numbers | Not Available | ||||||||||||||||||
| Name | IQ motif and SEC7 domain-containing protein 3 | ||||||||||||||||||
| Description | Not Available | ||||||||||||||||||
| Synonyms | Not Available | ||||||||||||||||||
| Gene Name | IQSEC3 | ||||||||||||||||||
| Protein Type | Enzyme | ||||||||||||||||||
| Biological Properties | |||||||||||||||||||
| General Function | Involved in ARF guanyl-nucleotide exchange factor activity | ||||||||||||||||||
| Specific Function | Acts as a guanine nucleotide exchange factor (GEF) for ARF1 | ||||||||||||||||||
| GO Classification |
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| Cellular Location |
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| Pathways | Not Available | ||||||||||||||||||
| Gene Properties | |||||||||||||||||||
| Chromosome Location | Chromosome:1 | ||||||||||||||||||
| Locus | 12p13.33 | ||||||||||||||||||
| SNPs | IQSEC3 | ||||||||||||||||||
| Gene Sequence |
>3549 bp ATGGAGAGCCTGCTGGAGAATCCGGTGCGCGCCGTGCTCTACCTCAAGGAGCTCACGGCC ATCGTGCAGAACCAGCAGAGCCTCATCCACACCCAGCGAGAGCGTATCGACGAGCTGGAG CGGCGGCTGGACGAGCTGAGCGCTGAGAACCGCAGCCTGTGGGAGCACCAGCAGCTGCTG CAAGCCCAGCCTCCGCCCGGGCTCGTCCCCCCGTCATCGGCCCCGCTGCCGGCCGCTCCG GCCACCGCTCCTGCCGCCGCCGCCAGGGCCCAGGAACCTCTCCAGGACCAGGGACAGCGC TCAGCAGCCGCGCCGCATCCCGCGCCCGATCGGCCGCCGCGTCAGCACCACGGACAGCTC CTGGAGCAGCCCCAGCGGGGCCCTGGCAGCAGGGCTCACACACCCCAGTCGCCCCACAAG CATCTGGGGACACAAGGGGCCGTGACTGACAAGGAGAAGGAGCGTCCCCCGAGTTGCTGC GCTGCTGCCGGAGCCCTCCTTCAGCACAAATCCCCCTCCGCCCTCGGCAAGGGCGTCCTG AGCAGGAGACCTGAGAATGAGACCGTGCTGCACCAGTTCTGCTGCCCAGCCGCCGACGCC TGCTCCGACCTGGCCTCCCAAAGTGATGGCTCCTGCACCCAGGCCGGTGGGGGCATGGAG GACTCCGTGGTGGCAGCGGCGGCGGTGGCAGCCGGCAGACCCAGTGCCCATGCCCCGAAG GCTCAAGCCCAGGAGCTGCAGGAGGAGGAGGAGCGGCCGGGGGCAGGGGCTGCCTCCCCA AGGGCTGGCCCCCAGCACAAGGCCTCCCCCGGCCGGCAGCAGCCTGCCCTGGCGACGGCG CTGTGCCCCCACGCCCCTGCCGCCTCCGATTACGAACTCTCCCTTGACCTAAAGAATAAA CAGATTGAAATGCTAGAACATAAGTACGGCGGTCACCTGGTGTCCCGGCGCGCCGCTTGC ACCATCCAAACCGCCTTCCGCCAATACCAGCTCAGCAAGAACTTCGAGAAAATCCGCAAC TCGCTTCTGGAGAGCCGCCTGCCACGGCGGATCTCCCTGCGCAAGGTGCGGTCACCCACG GCCGAGAGCCTGGCGGCCGAGAAAGCGCTCATGGAGGGCTACGGCCTCGTGGGGCTGCCG CTGGTGCGCTCGCCCTCCCTGCCGCCCACCTTCGCAGGCACCCTCACCGAGCTGGAGGAC TCCTTCACCGAGCAGGTGCAATCCCTGGCCAAGTCCATCGACGACGCGCTCAGCACGTGG AGCCTCAAGACCATGTGCTCCCTGCGGGAGAGTGGCGCTTACCAGCTCCACCAGGCCCTG CAGGCGGCCGCGGGGCCCCCAGGCCTGGAGGCCGAGGGGCGGGCGCCGGAGAGCGCGGGC CCCGGGCCCGGGGATGACGCCGCGGAGACCCCCGGCCTGCCCCCGGCCCACAGCGGGACC CTCATGATGGCTTTCCGGGACGTCACGGTGCAGATCGCCAACCAGAACATATCCGTCTCC TCCTCCACGGCTCTGTCGGTGGCCAACTGCCTGGGCGCTCAGACGGTCCAGGCCCCCGCA GAGCCCGCGGCGGGCAAGGCCGAGCAGGGCGAGACCTCTGGGCGGGAGGCCCCGGAAGCC CCCGCCGTGGGCCGGGAGGACGCGTCAGCCGAGGACTCATGCGCAGAGGCTGCGGCTAGT GGGGCGGCGGATGGGGCCACAGCCCCCAAAACAGAGGAGGAAGAGGAGGAGGAGGAGACG GCGGAGGTGGGGAGAGGGGCCGAGGCCGAGGCAGGCGACTTGGAGCAGCTGAGCAGCAGC AGCACGTCCACCAAGTCCGCCAAGTCAGGCTCGGAGGCGTCGGCCTCCGCCTCCAAGGAC GCCCTGCAGGCCATGATCCTGAGCCTGCCGCGCTACCACTGCGAGAACCCAGCCAGCTGC AAGTCGCCCACGCTCTCCACCGACACCCTGCGCAAGCGGCTCTACCGCATCGGCCTCAAC CTCTTCAACATAAACCCCGACAAGGGCATCCAGTTCCTGATCTCACGCGGCTTCATCCCG GACACCCCCATCGGTGTGGCCCATTTCCTCCTCCAGCGAAAGGGCCTCAGCCGCCAGATG ATTGGAGAGTTCCTGGGCAACAGCAAGAAGCAGTTCAACCGCGACGTGCTGGACTGCGTG GTGGACGAGATGGACTTCTCCAGCATGGAGCTGGACGAGGCCCTGCGCAAGTTCCAGGCA CACATCCGTGTGCAGGGGGAGGCTCAGAAGGTGGAGCGGCTCATTGAGGCCTTCAGCCAG CGCTACTGCATGTGCAACCCCGAAGTGGTTCAGCAGTTCCACAACCCCGACACCATCTTC ATCCTCGCCTTCGCCATCATCCTCCTCAACACCGACATGTACAGCCCCAACATCAAGCCT GACCGGAAGATGATGCTGGAGGACTTCATCCGAAACCTTCGAGGTGTGGACGATGGCGCT GACATCCCCAGGGAGCTGGTGGTAGGCATCTATGAGAGGATACAGCAGAAGGAGCTCAAG TCCAATGAGGACCACGTCACGTACGTCACCAAGGTGGAGAAGTCCATTGTGGGCATGAAG ACAGTGCTGTCCGTGCCCCACCGCCGCCTGGTGTGCTGCAGCCGGCTCTTCGAGGTGACG GATGTGAACAAGCTGCAGAAGCAGGCAGCGCATCAGAGGGAGGTGTTCCTCTTCAATGAC CTGCTGGTGATTCTCAAACTTTGCCCGAAGAAGAAGAGCTCCTCCACGTACACCTTTTGC AAGTCAGTTGGCCTGCTGGGCATGCAGTTCCAGCTCTTTGAGAACGAGTATTACTCTCAT GGCATCACACTGGTGACCCCGCTCTCGGGCTCCGAGAAGAAGCAGGTGCTGCATTTCTGT GCCCTGGGCTCGGACGAGATGCAGAAGTTCGTGGAGGACCTGAAGGAGTCCATTGCTGAG GTGACGGAGCTGGAGCAGATCCGAATAGAGTGGGAGCTGGAGAAGCAGCAGGGAACAAAG ACACTCTCCTTCAAGCCCTGCGGAGCCCAGGGGGACCCACAGTCAAAGCAAGGATCGCCG ACAGCCAAAAGGGAAGCCGCGCTCAGGGAGAGGCCGGCGGAGAGCACGGTGGAGGTGTCA ATTCACAACAGGCTTCAAACGTCCCAGCACAACTCCGGGCTGGGGGCCGAGAGGGGAGCG CCGGTGCCGCCGCCAGACCTGCAGCCTAGCCCCCCGAGACAGCAGACCCCACCACTGCCG CCGCCGCCACCCACGCCCCCGGGCACCCTGGTGCAGTGCCAGCAAATTGTCAAGGTCATT GTCCTGGACAAGCCCTGCCTGGCCCGCATGGAGCCCCTGCTGAGCCAGGCTCTCTCCTGC TACACCTCGTCGTCCTCTGACTCCTGCGGCTCCACACCCCTGGGCGGTCCCGGCTCTCCG GTCAAGGTCACCCACCAGCCTCCGCTGCCCCCGCCCCCACCCCCCTACAACCACCCTCAC CAGTTCTGTCCCCCAGGCTCCCTGCTGCACGGGCACCGCTACTCCAGTGGCTCAAGGAGC CTGGTGTAG |
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| Protein Properties | |||||||||||||||||||
| Number of Residues | 1182 | ||||||||||||||||||
| Molecular Weight | 127619.9 | ||||||||||||||||||
| Theoretical pI | 6.49 | ||||||||||||||||||
| Pfam Domain Function |
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| Signals |
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| Transmembrane Regions |
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| Protein Sequence |
>IQ motif and SEC7 domain-containing protein 3 MESLLENPVRAVLYLKELTAIVQNQQSLIHTQRERIDELERRLDELSAENRSLWEHQQLL QAQPPPGLVPPSSAPLPAAPATAPAAAARAQEPLQDQGQRSAAAPHPAPDRPPRQHHGQL LEQPQRGPGSRAHTPQSPHKHLGTQGAVTDKEKERPPSCCAAAGALLQHKSPSALGKGVL SRRPENETVLHQFCCPAADACSDLASQSDGSCTQAGGGMEDSVVAAAAVAAGRPSAHAPK AQAQELQEEEERPGAGAASPRAGPQHKASPGRQQPALATALCPHAPAASDYELSLDLKNK QIEMLEHKYGGHLVSRRAACTIQTAFRQYQLSKNFEKIRNSLLESRLPRRISLRKVRSPT AESLAAEKALMEGYGLVGLPLVRSPSLPPTFAGTLTELEDSFTEQVQSLAKSIDDALSTW SLKTMCSLRESGAYQLHQALQAAAGPPGLEAEGRAPESAGPGPGDDAAETPGLPPAHSGT LMMAFRDVTVQIANQNISVSSSTALSVANCLGAQTVQAPAEPAAGKAEQGETSGREAPEA PAVGREDASAEDSCAEAAASGAADGATAPKTEEEEEEEETAEVGRGAEAEAGDLEQLSSS STSTKSAKSGSEASASASKDALQAMILSLPRYHCENPASCKSPTLSTDTLRKRLYRIGLN LFNINPDKGIQFLISRGFIPDTPIGVAHFLLQRKGLSRQMIGEFLGNSKKQFNRDVLDCV VDEMDFSSMELDEALRKFQAHIRVQGEAQKVERLIEAFSQRYCMCNPEVVQQFHNPDTIF ILAFAIILLNTDMYSPNIKPDRKMMLEDFIRNLRGVDDGADIPRELVVGIYERIQQKELK SNEDHVTYVTKVEKSIVGMKTVLSVPHRRLVCCSRLFEVTDVNKLQKQAAHQREVFLFND LLVILKLCPKKKSSSTYTFCKSVGLLGMQFQLFENEYYSHGITLVTPLSGSEKKQVLHFC ALGSDEMQKFVEDLKESIAEVTELEQIRIEWELEKQQGTKTLSFKPCGAQGDPQSKQGSP TAKREAALRERPAESTVEVSIHNRLQTSQHNSGLGAERGAPVPPPDLQPSPPRQQTPPLP PPPPTPPGTLVQCQQIVKVIVLDKPCLARMEPLLSQALSCYTSSSSDSCGSTPLGGPGSP VKVTHQPPLPPPPPPYNHPHQFCPPGSLLHGHRYSSGSRSLV |
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| External Links | |||||||||||||||||||
| GenBank ID Protein | 282721018 | ||||||||||||||||||
| UniProtKB/Swiss-Prot ID | Q9UPP2 | ||||||||||||||||||
| UniProtKB/Swiss-Prot Entry Name | IQEC3_HUMAN | ||||||||||||||||||
| PDB IDs | Not Available | ||||||||||||||||||
| GenBank Gene ID | NM_001170738.1 | ||||||||||||||||||
| GeneCard ID | IQSEC3 | ||||||||||||||||||
| GenAtlas ID | IQSEC3 | ||||||||||||||||||
| HGNC ID | HGNC:29193 | ||||||||||||||||||
| References | |||||||||||||||||||
| General References | Not Available | ||||||||||||||||||