Identification |
HMDB Protein ID
| CDBP05083 |
Secondary Accession Numbers
| Not Available |
Name
| Guanine nucleotide-binding protein G(z) subunit alpha |
Description
| Not Available |
Synonyms
|
- G(x) alpha chain
- Gz-alpha
|
Gene Name
| GNAZ |
Protein Type
| Receptor |
Biological Properties |
General Function
| Involved in signal transducer activity |
Specific Function
| Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems |
GO Classification
|
Function |
purine nucleotide binding |
binding |
nucleotide binding |
guanyl nucleotide binding |
guanyl ribonucleotide binding |
gtp binding |
molecular transducer activity |
signal transducer activity |
Process |
regulation of cellular process |
signal transduction |
signaling |
signaling pathway |
cell surface receptor linked signaling pathway |
g-protein coupled receptor protein signaling pathway |
biological regulation |
regulation of biological process |
|
Cellular Location
|
- Lipid-anchor
- Membrane
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Chromosome:2 |
Locus
| 22q11.22 |
SNPs
| GNAZ |
Gene Sequence
|
>1068 bp
ATGGGATGTCGGCAAAGCTCAGAGGAAAAAGAAGCAGCCCGGCGGTCCCGGAGAATTGAC
CGCCACCTGCGCTCAGAGAGCCAGCGGCAACGCCGCGAAATCAAGCTGCTCCTGCTGGGC
ACCAGCAACTCAGGCAAGAGCACCATCGTCAAACAGATGAAGATCATCCACAGCGGCGGC
TTCAACCTGGAGGCCTGCAAGGAGTACAAGCCCCTCATCATCTACAATGCCATCGACTCG
CTGACCCGCATCATCCGGGCCCTGGCCGCCCTCAGGATCGACTTCCACAACCCCGACCGC
GCCTACGATGCTGTGCAGCTCTTTGCGCTGACGGGCCCCGCTGAGAGCAAGGGCGAGATC
ACACCCGAGCTGCTGGGTGTCATGCGACGGCTCTGGGCCGACCCAGGGGCACAGGCCTGC
TTCAGCCGCTCCAGCGAGTACCACCTGGAGGACAACGCGGCCTACTACCTGAACGACCTG
GAGCGCATCGCCGCAGCTGACTATATCCCCACTGTCGAGGACATCCTGCGCTCCCGGGAC
ATGACCACGGGCATTGTGGAGAACAAGTTCACCTTCAAGGAGCTCACCTTCAAGATGGTG
GACGTGGGGGGGCAGAGGTCAGAGCGCAAAAAGTGGATCCACTGCTTCGAGGGCGTCACA
GCCATCATCTTCTGTGTGGAGCTCAGCGGCTACGACCTGAAACTCTACGAGGATAACCAG
ACAAGTCGGATGGCAGAGAGCTTGCGCCTCTTTGACTCCATCTGCAACAACAACTGGTTC
ATCAACACCTCACTCATCCTCTTCCTGAACAAGAAGGACCTGCTGGCAGAGAAGATCCGC
CGCATCCCGCTCACCATCTGCTTTCCCGAGTACAAGGGCCAGAACACGTACGAGGAGGCC
GCTGTCTACATCCAGCGGCAGTTTGAAGACCTGAACCGCAACAAGGAGACCAAGGAGATC
TACTCCCACTTCACCTGCGCCACCGACACCAGTAACATCCAGTTTGTCTTCGACGCGGTG
ACAGACGTCATCATACAGAACAATCTCAAGTACATTGGCCTTTGCTGA
|
Protein Properties |
Number of Residues
| 355 |
Molecular Weight
| 40923.3 |
Theoretical pI
| 7.69 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
|
Protein Sequence
|
>Guanine nucleotide-binding protein G(z) subunit alpha
MGCRQSSEEKEAARRSRRIDRHLRSESQRQRREIKLLLLGTSNSGKSTIVKQMKIIHSGG
FNLEACKEYKPLIIYNAIDSLTRIIRALAALRIDFHNPDRAYDAVQLFALTGPAESKGEI
TPELLGVMRRLWADPGAQACFSRSSEYHLEDNAAYYLNDLERIAAADYIPTVEDILRSRD
MTTGIVENKFTFKELTFKMVDVGGQRSERKKWIHCFEGVTAIIFCVELSGYDLKLYEDNQ
TSRMAESLRLFDSICNNNWFINTSLILFLNKKDLLAEKIRRIPLTICFPEYKGQNTYEEA
AVYIQRQFEDLNRNKETKEIYSHFTCATDTSNIQFVFDAVTDVIIQNNLKYIGLC
|
External Links |
GenBank ID Protein
| 20147691 |
UniProtKB/Swiss-Prot ID
| P19086 |
UniProtKB/Swiss-Prot Entry Name
| GNAZ_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| AF493899 |
GeneCard ID
| GNAZ |
GenAtlas ID
| GNAZ |
HGNC ID
| HGNC:4395 |
References |
General References
| Not Available |