Identification
HMDB Protein ID CDBP05083
Secondary Accession Numbers Not Available
Name Guanine nucleotide-binding protein G(z) subunit alpha
Description Not Available
Synonyms
  1. G(x) alpha chain
  2. Gz-alpha
Gene Name GNAZ
Protein Type Receptor
Biological Properties
General Function Involved in signal transducer activity
Specific Function Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems
GO Classification
Function
purine nucleotide binding
binding
nucleotide binding
guanyl nucleotide binding
guanyl ribonucleotide binding
gtp binding
molecular transducer activity
signal transducer activity
Process
regulation of cellular process
signal transduction
signaling
signaling pathway
cell surface receptor linked signaling pathway
g-protein coupled receptor protein signaling pathway
biological regulation
regulation of biological process
Cellular Location
  1. Lipid-anchor
  2. Membrane
Pathways
Gene Properties
Chromosome Location Chromosome:2
Locus 22q11.22
SNPs GNAZ
Gene Sequence
>1068 bp
ATGGGATGTCGGCAAAGCTCAGAGGAAAAAGAAGCAGCCCGGCGGTCCCGGAGAATTGAC
CGCCACCTGCGCTCAGAGAGCCAGCGGCAACGCCGCGAAATCAAGCTGCTCCTGCTGGGC
ACCAGCAACTCAGGCAAGAGCACCATCGTCAAACAGATGAAGATCATCCACAGCGGCGGC
TTCAACCTGGAGGCCTGCAAGGAGTACAAGCCCCTCATCATCTACAATGCCATCGACTCG
CTGACCCGCATCATCCGGGCCCTGGCCGCCCTCAGGATCGACTTCCACAACCCCGACCGC
GCCTACGATGCTGTGCAGCTCTTTGCGCTGACGGGCCCCGCTGAGAGCAAGGGCGAGATC
ACACCCGAGCTGCTGGGTGTCATGCGACGGCTCTGGGCCGACCCAGGGGCACAGGCCTGC
TTCAGCCGCTCCAGCGAGTACCACCTGGAGGACAACGCGGCCTACTACCTGAACGACCTG
GAGCGCATCGCCGCAGCTGACTATATCCCCACTGTCGAGGACATCCTGCGCTCCCGGGAC
ATGACCACGGGCATTGTGGAGAACAAGTTCACCTTCAAGGAGCTCACCTTCAAGATGGTG
GACGTGGGGGGGCAGAGGTCAGAGCGCAAAAAGTGGATCCACTGCTTCGAGGGCGTCACA
GCCATCATCTTCTGTGTGGAGCTCAGCGGCTACGACCTGAAACTCTACGAGGATAACCAG
ACAAGTCGGATGGCAGAGAGCTTGCGCCTCTTTGACTCCATCTGCAACAACAACTGGTTC
ATCAACACCTCACTCATCCTCTTCCTGAACAAGAAGGACCTGCTGGCAGAGAAGATCCGC
CGCATCCCGCTCACCATCTGCTTTCCCGAGTACAAGGGCCAGAACACGTACGAGGAGGCC
GCTGTCTACATCCAGCGGCAGTTTGAAGACCTGAACCGCAACAAGGAGACCAAGGAGATC
TACTCCCACTTCACCTGCGCCACCGACACCAGTAACATCCAGTTTGTCTTCGACGCGGTG
ACAGACGTCATCATACAGAACAATCTCAAGTACATTGGCCTTTGCTGA
Protein Properties
Number of Residues 355
Molecular Weight 40923.3
Theoretical pI 7.69
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["None"]
Protein Sequence
>Guanine nucleotide-binding protein G(z) subunit alpha
MGCRQSSEEKEAARRSRRIDRHLRSESQRQRREIKLLLLGTSNSGKSTIVKQMKIIHSGG
FNLEACKEYKPLIIYNAIDSLTRIIRALAALRIDFHNPDRAYDAVQLFALTGPAESKGEI
TPELLGVMRRLWADPGAQACFSRSSEYHLEDNAAYYLNDLERIAAADYIPTVEDILRSRD
MTTGIVENKFTFKELTFKMVDVGGQRSERKKWIHCFEGVTAIIFCVELSGYDLKLYEDNQ
TSRMAESLRLFDSICNNNWFINTSLILFLNKKDLLAEKIRRIPLTICFPEYKGQNTYEEA
AVYIQRQFEDLNRNKETKEIYSHFTCATDTSNIQFVFDAVTDVIIQNNLKYIGLC
GenBank ID Protein 20147691
UniProtKB/Swiss-Prot ID P19086
UniProtKB/Swiss-Prot Entry Name GNAZ_HUMAN
PDB IDs Not Available
GenBank Gene ID AF493899
GeneCard ID GNAZ
GenAtlas ID GNAZ
HGNC ID HGNC:4395
References
General References Not Available