Identification |
HMDB Protein ID
| CDBP05082 |
Secondary Accession Numbers
| Not Available |
Name
| GRB2-related adapter protein |
Description
| Not Available |
Synonyms
|
Not Available
|
Gene Name
| GRAP |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in protein binding |
Specific Function
| Couples signals from receptor and cytoplasmic tyrosine kinases to the Ras signaling pathway |
GO Classification
|
Function |
binding |
protein binding |
|
Cellular Location
|
Not Available
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Chromosome:1 |
Locus
| 17p11.2 |
SNPs
| GRAP |
Gene Sequence
|
>654 bp
ATGGAGTCCGTGGCCCTGTACAGCTTTCAGGCTACAGAGAGCGACGAGCTGGCCTTCAAC
AAGGGAGACACACTCAAGATCCTGAACATGGAGGATGACCAGAACTGGTACAAGGCCGAG
CTCCGGGGTGTCGAGGGATTTATTCCCAAGAACTACATCCGCGTCAAGCCCCATCCGTGG
TACTCGGGCAGGATTTCCCGGCAGCTGGCCGAAGAGATTCTGATGAAGCGGAACCATCTG
GGAGCCTTCCTGATCCGGGAGAGTGAGAGCTCCCCAGGGGAGTTCTCTGTGTCTGTGAAC
TATGGAGACCAGGTGCAGCACTTCAAGGTGCTGCGTGAGGCCTCGGGGAAGTACTTCCTG
TGGGAGGAGAAGTTCAACTCCCTCAACGAGCTGGTCGACTTCTACCGCACCACCACCATC
GCCAAGAAGCGGCAGATCTTCCTGCGCGACGAGGAGCCCTTGCTCAAGTCACCTGGGGCC
TGCTTTGCCCAGGCCCAGTTTGACTTCTCAGCCCAGGACCCCTCGCAGCTCAGCTTCCGC
CGTGGCGACATCATTGAGGTCCTGGAGCGCCCAGACCCCCACTGGTGGCGGGGCCGGTCC
TGCGGGCGCGTTGGCTTCTTCCCACGGAGTTACGTGCAGCCCGTGCACCTGTGA
|
Protein Properties |
Number of Residues
| 217 |
Molecular Weight
| 25336.4 |
Theoretical pI
| 7.06 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
|
Protein Sequence
|
>GRB2-related adapter protein
MESVALYSFQATESDELAFNKGDTLKILNMEDDQNWYKAELRGVEGFIPKNYIRVKPHPW
YSGRISRQLAEEILMKRNHLGAFLIRESESSPGEFSVSVNYGDQVQHFKVLREASGKYFL
WEEKFNSLNELVDFYRTTTIAKKRQIFLRDEEPLLKSPGACFAQAQFDFSAQDPSQLSFR
RGDIIEVLERPDPHWWRGRSCGRVGFFPRSYVQPVHL
|
External Links |
GenBank ID Protein
| 5729856 |
UniProtKB/Swiss-Prot ID
| Q13588 |
UniProtKB/Swiss-Prot Entry Name
| GRAP_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| NM_006613.3 |
GeneCard ID
| GRAP |
GenAtlas ID
| GRAP |
HGNC ID
| HGNC:4562 |
References |
General References
| Not Available |