Identification |
HMDB Protein ID
| CDBP05049 |
Secondary Accession Numbers
| Not Available |
Name
| Guanine nucleotide-binding protein G(k) subunit alpha |
Description
| Not Available |
Synonyms
|
- G(i) alpha-3
|
Gene Name
| GNAI3 |
Protein Type
| Receptor |
Biological Properties |
General Function
| Involved in signal transducer activity |
Specific Function
| Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. G(k) is the stimulatory G protein of receptor- regulated K(+) channels |
GO Classification
|
Function |
guanyl ribonucleotide binding |
gtp binding |
molecular transducer activity |
signal transducer activity |
purine nucleotide binding |
binding |
nucleotide binding |
guanyl nucleotide binding |
Process |
biological regulation |
regulation of biological process |
regulation of cellular process |
signal transduction |
signaling |
signaling pathway |
cell surface receptor linked signaling pathway |
g-protein coupled receptor protein signaling pathway |
|
Cellular Location
|
Not Available
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Chromosome:1 |
Locus
| 1p13 |
SNPs
| GNAI3 |
Gene Sequence
|
>1065 bp
ATGGGCTGCACGTTGAGCGCCGAAGACAAGGCGGCAGTGGAGCGAAGCAAGATGATCGAC
CGCAACTTACGGGAGGACGGGGAAAAAGCGGCCAAAGAAGTGAAGCTGCTGCTACTCGGT
GCTGGAGAATCTGGTAAAAGCACCATTGTGAAACAGATGAAAATCATTCATGAGGATGGC
TATTCAGAGGATGAATGTAAACAATATAAAGTAGTTGTCTACAGCAATACTATACAGTCC
ATCATTGCAATCATAAGAGCCATGGGACGGCTAAAGATTGACTTTGGGGAAGCTGCCAGG
GCAGATGATGCCCGGCAATTATTTGTTTTAGCTGGCAGTGCTGAAGAAGGAGTCATGACT
CCAGAACTAGCAGGAGTGATTAAACGGTTATGGCGAGATGGTGGGGTACAAGCTTGCTTC
AGCAGATCCAGGGAATATCAGCTCAATGATTCTGCTTCATATTATCTAAATGATCTGGAT
AGAATATCCCAGTCTAACTACATTCCAACTCAGCAAGATGTTCTTCGGACGAGAGTGAAG
ACCACAGGCATTGTAGAAACACATTTCACCTTCAAAGACCTATACTTCAAGATGTTTGAT
GTAGGTGGCCAAAGATCAGAACGAAAAAAGTGGATTCACTGTTTTGAGGGAGTGACAGCA
ATTATCTTCTGTGTGGCCCTCAGTGATTATGACCTTGTTCTGGCTGAGGACGAGGAGATG
AACCGAATGCATGAAAGCATGAAACTGTTTGACAGCATTTGTAATAACAAATGGTTTACA
GAAACTTCAATCATTCTCTTCCTTAACAAGAAAGACCTTTTTGAGGAAAAAATAAAGAGG
AGTCCGTTAACTATCTGTTATCCAGAATACACAGGTTCCAATACATATGAAGAGGCAGCT
GCCTATATTCAATGCCAGTTTGAAGATCTGAACAGAAGAAAAGATACCAAGGAGATCTAT
ACTCACTTCACCTGTGCCACAGACACGAAGAATGTGCAGTTTGTTTTTGATGCTGTTACA
GATGTCATCATTAAAAACAACTTAAAGGAATGTGGACTTTATTGA
|
Protein Properties |
Number of Residues
| 354 |
Molecular Weight
| 40531.8 |
Theoretical pI
| 5.37 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
|
Protein Sequence
|
>Guanine nucleotide-binding protein G(k) subunit alpha
MGCTLSAEDKAAVERSKMIDRNLREDGEKAAKEVKLLLLGAGESGKSTIVKQMKIIHEDG
YSEDECKQYKVVVYSNTIQSIIAIIRAMGRLKIDFGEAARADDARQLFVLAGSAEEGVMT
PELAGVIKRLWRDGGVQACFSRSREYQLNDSASYYLNDLDRISQSNYIPTQQDVLRTRVK
TTGIVETHFTFKDLYFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEM
NRMHESMKLFDSICNNKWFTETSIILFLNKKDLFEEKIKRSPLTICYPEYTGSNTYEEAA
AYIQCQFEDLNRRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKECGLY
|
External Links |
GenBank ID Protein
| 20147707 |
UniProtKB/Swiss-Prot ID
| P08754 |
UniProtKB/Swiss-Prot Entry Name
| GNAI3_HUMAN |
PDB IDs
|
|
GenBank Gene ID
| AF493907 |
GeneCard ID
| GNAI3 |
GenAtlas ID
| GNAI3 |
HGNC ID
| HGNC:4387 |
References |
General References
| Not Available |