| Identification |
|---|
| HMDB Protein ID
| CDBP05046 |
| Secondary Accession Numbers
| Not Available |
| Name
| Guanine nucleotide-binding protein subunit alpha-14 |
| Description
| Not Available |
| Synonyms
|
- G alpha-14
- G-protein subunit alpha-14
|
| Gene Name
| GNA14 |
| Protein Type
| Receptor |
| Biological Properties |
|---|
| General Function
| Involved in signal transducer activity |
| Specific Function
| Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems |
| GO Classification
|
| Function |
| purine nucleotide binding |
| binding |
| nucleotide binding |
| guanyl nucleotide binding |
| guanyl ribonucleotide binding |
| gtp binding |
| molecular transducer activity |
| signal transducer activity |
| Process |
| signal transduction |
| macromolecule modification |
| protein modification process |
| signaling |
| signaling pathway |
| cell surface receptor linked signaling pathway |
| g-protein coupled receptor protein signaling pathway |
| metabolic process |
| macromolecule metabolic process |
| protein amino acid adp-ribosylation |
| biological regulation |
| regulation of biological process |
| post-translational protein modification |
| regulation of cellular process |
|
| Cellular Location
|
Not Available
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:9 |
| Locus
| 9q21 |
| SNPs
| GNA14 |
| Gene Sequence
|
>1068 bp
ATGGCCGGCTGCTGCTGCCTGTCCGCGGAGGAGAAGGAGTCGCAGCGCATCAGCGCGGAG
ATCGAGCGACAGCTTCGTCGGGACAAGAAGGACGCGCGCCGTGAGCTTAAGCTGCTGCTG
CTGGGAACTGGTGAAAGTGGGAAAAGCACCTTTATCAAGCAGATGAGAATTATCCATGGG
TCTGGTTACAGCGACGAAGACAGAAAGGGGTTCACGAAGCTGGTTTACCAAAACATATTC
ACCGCCATGCAAGCCATGATCAGAGCGATGGACACGCTAAGGATACAGTATGTGTGTGAA
CAGAATAAGGAAAATGCCCAGATAATCAGAGAAGTGGAAGTGGACAAGGTCTCCATGCTC
TCCAGGGAGCAGGTGGAGGCCATCAAGCAGCTCTGGCAAGATCCAGGCATCCAGGAGTGT
TACGACAGGAGGAGGGAGTACCAGCTGTCGGACTCTGCCAAATATTACCTGACTGACATT
GACCGCATCGCCACACCATCATTCGTGCCTACCCAACAAGATGTGCTTCGCGTCCGAGTG
CCCACCACCGGCATCATTGAGTATCCATTTGACTTGGAAAACATCATCTTTCGGATGGTG
GATGTTGGTGGCCAACGATCGGAAAGACGGAAGTGGATTCACTGCTTTGAGAGTGTCACC
TCCATTATTTTCTTGGTTGCTCTGAGTGAATATGACCAGGTCCTGGCTGAGTGTGACAAC
GAGAATCGCATGGAAGAGAGCAAAGCCTTATTTAAAACCATCATCACCTACCCCTGGTTT
CTGAATTCGTCTGTGATTTTATTCTTGAACAAGAAGGATCTTTTGGAAGAGAAAATCATG
TACTCTCATCTAATTAGCTATTTCCCAGAATACACAGGACCGAAACAGGATGTCAGAGCT
GCCAGAGACTTTATCCTGAAGCTTTACCAAGATCAGAATCCTGACAAAGAGAAAGTCATC
TACTCTCACTTCACATGTGCTACAGATACAGACAATATTCGCTTTGTGTTTGCTGCTGTC
AAAGACACAATTCTACAGCTAAACCTAAGGGAATTCAACCTTGTCTAA
|
| Protein Properties |
|---|
| Number of Residues
| 355 |
| Molecular Weight
| 41570.2 |
| Theoretical pI
| 5.86 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Guanine nucleotide-binding protein subunit alpha-14
MAGCCCLSAEEKESQRISAEIERQLRRDKKDARRELKLLLLGTGESGKSTFIKQMRIIHG
SGYSDEDRKGFTKLVYQNIFTAMQAMIRAMDTLRIQYVCEQNKENAQIIREVEVDKVSML
SREQVEAIKQLWQDPGIQECYDRRREYQLSDSAKYYLTDIDRIATPSFVPTQQDVLRVRV
PTTGIIEYPFDLENIIFRMVDVGGQRSERRKWIHCFESVTSIIFLVALSEYDQVLAECDN
ENRMEESKALFKTIITYPWFLNSSVILFLNKKDLLEEKIMYSHLISYFPEYTGPKQDVRA
ARDFILKLYQDQNPDKEKVIYSHFTCATDTDNIRFVFAAVKDTILQLNLREFNLV
|
| External Links |
|---|
| GenBank ID Protein
| 4336774 |
| UniProtKB/Swiss-Prot ID
| O95837 |
| UniProtKB/Swiss-Prot Entry Name
| GNA14_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AF105201 |
| GeneCard ID
| GNA14 |
| GenAtlas ID
| GNA14 |
| HGNC ID
| HGNC:4382 |
| References |
|---|
| General References
| Not Available |