| Identification |
|---|
| HMDB Protein ID
| CDBP05031 |
| Secondary Accession Numbers
| Not Available |
| Name
| T-cell surface glycoprotein CD1a |
| Description
| Not Available |
| Synonyms
|
- CD1a antigen
- T-cell surface antigen T6/Leu-6
- hTa1 thymocyte antigen
|
| Gene Name
| CD1A |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in immune response |
| Specific Function
| Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells |
| GO Classification
|
| Component |
| cell part |
| macromolecular complex |
| protein complex |
| mhc protein complex |
| mhc class i protein complex |
| membrane |
| Process |
| antigen processing and presentation |
| immune system process |
| immune response |
|
| Cellular Location
|
- Cell membrane
- Endosome membrane
- Single-pass type I membrane protein
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 1q22-q23 |
| SNPs
| CD1A |
| Gene Sequence
|
>984 bp
ATGCTGTTTTTGCTACTTCCATTGTTAGCTGTTCTCCCAGGTGATGGCAATGCAGACGGG
CTCAAGGAGCCTCTCTCCTTCCATGTCATCTGGATCGCATCCTTTTACAACCATTCCTGG
AAACAAAATCTGGTCTCAGGTTGGCTGAGTGATTTGCAGACTCATACCTGGGACAGCAAT
TCCAGCACCATCGTTTTCCTGTGGCCCTGGTCCAGGGGAAACTTCAGCAATGAGGAGTGG
AAGGAACTGGAAACATTATTCCGTATACGCACCATTCGGTCATTTGAGGGAATTCGTAGA
TACGCCCATGAATTGCAGTTTGAATATCCTTTTGAGATACAGGTGACAGGAGGCTGTGAG
CTGCACTCTGGAAAGGTCTCAGGAAGCTTCTTGCAGTTAGCTTATCAAGGATCAGACTTT
GTGAGCTTCCAGAACAATTCATGGTTGCCATATCCAGTGGCTGGGAATATGGCCAAGCAT
TTCTGCAAAGTGCTCAATCAGAATCAGCATGAAAATGACATAACACACAATCTTCTCAGT
GACACCTGCCCACGTTTCATCTTGGGTCTTCTTGATGCAGGAAAGGCACATCTCCAGCGG
CAAGTGAAGCCCGAGGCCTGGCTGTCCCATGGCCCCAGTCCTGGCCCTGGCCATCTGCAG
CTTGTGTGCCATGTCTCAGGATTCTACCCAAAGCCCGTGTGGGTGATGTGGATGCGGGGT
GAGCAGGAGCAGCAGGGCACTCAGCGAGGGGACATCTTGCCCAGTGCTGATGGGACATGG
TATCTCCGCGCAACCCTGGAGGTGGCCGCTGGGGAGGCAGCTGACCTGTCCTGTCGGGTG
AAGCACAGCAGTCTAGAGGGCCAGGACATCGTCCTCTACTGGGAGCATCACAGTTCCGTG
GGCTTCATCATCTTGGCGGTGATAGTGCCTTTACTTCTTCTGATAGGTCTTGCGCTTTGG
TTCAGGAAACGCTGTTTCTGTTAA
|
| Protein Properties |
|---|
| Number of Residues
| 327 |
| Molecular Weight
| 37077.1 |
| Theoretical pI
| 6.79 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>T-cell surface glycoprotein CD1a
MLFLLLPLLAVLPGDGNADGLKEPLSFHVTWIASFYNHSWKQNLVSGWLSDLQTHTWDSN
SSTIVFLCPWSRGNFSNEEWKELETLFRIRTIRSFEGIRRYAHELQFEYPFEIQVTGGCE
LHSGKVSGSFLQLAYQGSDFVSFQNNSWLPYPVAGNMAKHFCKVLNQNQHENDITHNLLS
DTCPRFILGLLDAGKAHLQRQVKPEAWLSHGPSPGPGHLQLVCHVSGFYPKPVWVMWMRG
EQEQQGTQRGDILPSADGTWYLRATLEVAAGEAADLSCRVKHSSLEGQDIVLYWEHHSSV
GFIILAVIVPLLLLIGLALWFRKRCFC
|
| External Links |
|---|
| GenBank ID Protein
| 180036 |
| UniProtKB/Swiss-Prot ID
| P06126 |
| UniProtKB/Swiss-Prot Entry Name
| CD1A_HUMAN |
| PDB IDs
|
|
| GenBank Gene ID
| M28825 |
| GeneCard ID
| CD1A |
| GenAtlas ID
| CD1A |
| HGNC ID
| HGNC:1634 |
| References |
|---|
| General References
| Not Available |