Identification
HMDB Protein ID CDBP05024
Secondary Accession Numbers Not Available
Name Lambda-crystallin homolog
Description Not Available
Synonyms
  1. Gul3DH
  2. L-gulonate 3-dehydrogenase
Gene Name CRYL1
Protein Type Enzyme
Biological Properties
General Function Involved in 3-hydroxyacyl-CoA dehydrogenase activity
Specific Function Not Available
GO Classification
Biological Process
fatty acid metabolic process
Cellular Component
cytosol
Function
binding
nucleotide binding
catalytic activity
nad or nadh binding
oxidoreductase activity, acting on the ch-oh group of donors, nad or nadp as acceptor
nad binding
3-hydroxyacyl-coa dehydrogenase activity
oxidoreductase activity, acting on ch-oh group of donors
oxidoreductase activity
Molecular Function
3-hydroxyacyl-CoA dehydrogenase activity
L-gulonate 3-dehydrogenase activity
NAD+ binding
Process
carboxylic acid metabolic process
monocarboxylic acid metabolic process
fatty acid metabolic process
metabolic process
cellular metabolic process
organic acid metabolic process
oxoacid metabolic process
Cellular Location
  1. Cytoplasm
Pathways
Gene Properties
Chromosome Location 13
Locus 13q12.11
SNPs CRYL1
Gene Sequence
>960 bp
ATGGCGTCCTCCGCGGCCGGCTGCGTGGTGATCGTTGGCAGTGGAGTCATTGGGCGAAGC
TGGGCCATGCTGTTTGCCAGTGGAGGCTTCCAGGTGAAACTCTATGACATTGAGCAACAG
CAGATAAGGAACGCCCTGGAAAACATCAGAAAGGAGATGAAGTTGCTGGAGCAGGCAGGT
TCTCTGAAAGGCTCCCTGAGTGTGGAAGAGCAGCTGTCACTCATCAGTGGTTGTCCCAAT
ATCCAAGAAGCAGTAGAGGGTGCCATGCACATTCAGGAATGTGTTCCAGAAGATCTAGAA
CTGAAGAAGAAGATTTTTGCTCAGTTAGATTCCATCATTGATGATCGAGTGATCTTAAGC
AGTTCCACTTCTTGTCTCATGCCTTCCAAGTTGTTTGCTGGCTTGGTCCATGTGAAGCAA
TGCATCGTGGCTCATCCTGTGAATCCGCCATACTACATCCCGCTGGTTGAGCTGGTCCCC
CACCCGGAGACGGCCCCTACGACAGTGGACAGAACCCACGCCCTGATGAAGAAGATTGGA
CAGTGCCCCATGCGAGTCCAGAAGGAGGTGGCCGGCTTCGTTCTGAACCGCCTGCAATAT
GCAATCATCAGCGAGGCCTGGCGGCTAGTGGAGGAAGGAATCGTGTCTCCTAGTGACCTG
GACCTTGTCATGTCAGAAGGGTTGGGCATGCGGTATGCATTCATTGGACCCCTGGAAACC
ATGCATCTCAATGCAGAAGGTATGTTAAGCTACTGCGACAGATACAGCGAAGGCATAAAA
CATGTCCTACAGACTTTTGGACCCATTCCAGAGTTTTCCAGGGCCACTGCTGAGAAGGTT
AACCAGGACATGTGCATGAAGGTCCCTGATGACCCGGAGCACTTAGCTGCCAGGAGGCAG
TGGAGGGACGAGTGCCTCATGAGACTCGCCAAGTTGAAGAGTCAAGTGCAGCCCCAGTGA
Protein Properties
Number of Residues 319
Molecular Weight 35418.91
Theoretical pI 6.175
Pfam Domain Function
Signals Not Available
Transmembrane Regions Not Available
Protein Sequence
>Lambda-crystallin homolog
MASSAAGCVVIVGSGVIGRSWAMLFASGGFQVKLYDIEQQQIRNALENIRKEMKLLEQAG
SLKGSLSVEEQLSLISGCPNIQEAVEGAMHIQECVPEDLELKKKIFAQLDSIIDDRVILS
SSTSCLMPSKLFAGLVHVKQCIVAHPVNPPYYIPLVELVPHPETAPTTVDRTHALMKKIG
QCPMRVQKEVAGFVLNRLQYAIISEAWRLVEEGIVSPSDLDLVMSEGLGMRYAFIGPLET
MHLNAEGMLSYCDRYSEGIKHVLQTFGPIPEFSRATAEKVNQDMCMKVPDDPEHLAARRQ
WRDECLMRLAKLKSQVQPQ
GenBank ID Protein 115430219
UniProtKB/Swiss-Prot ID Q9Y2S2
UniProtKB/Swiss-Prot Entry Name CRYL1_HUMAN
PDB IDs
GenBank Gene ID NM_015974.2
GeneCard ID CRYL1
GenAtlas ID CRYL1
HGNC ID HGNC:18246
References
General References Not Available