Identification |
HMDB Protein ID
| CDBP05024 |
Secondary Accession Numbers
| Not Available |
Name
| Lambda-crystallin homolog |
Description
| Not Available |
Synonyms
|
- Gul3DH
- L-gulonate 3-dehydrogenase
|
Gene Name
| CRYL1 |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in 3-hydroxyacyl-CoA dehydrogenase activity |
Specific Function
| Not Available |
GO Classification
|
Biological Process |
fatty acid metabolic process |
Cellular Component |
cytosol |
Function |
binding |
nucleotide binding |
catalytic activity |
nad or nadh binding |
oxidoreductase activity, acting on the ch-oh group of donors, nad or nadp as acceptor |
nad binding |
3-hydroxyacyl-coa dehydrogenase activity |
oxidoreductase activity, acting on ch-oh group of donors |
oxidoreductase activity |
Molecular Function |
3-hydroxyacyl-CoA dehydrogenase activity |
L-gulonate 3-dehydrogenase activity |
NAD+ binding |
Process |
carboxylic acid metabolic process |
monocarboxylic acid metabolic process |
fatty acid metabolic process |
metabolic process |
cellular metabolic process |
organic acid metabolic process |
oxoacid metabolic process |
|
Cellular Location
|
- Cytoplasm
|
Pathways
|
Name | SMPDB/Pathwhiz | KEGG | Pentose and glucuronate interconversions | Not Available | |
|
Gene Properties |
Chromosome Location
| 13 |
Locus
| 13q12.11 |
SNPs
| CRYL1 |
Gene Sequence
|
>960 bp
ATGGCGTCCTCCGCGGCCGGCTGCGTGGTGATCGTTGGCAGTGGAGTCATTGGGCGAAGC
TGGGCCATGCTGTTTGCCAGTGGAGGCTTCCAGGTGAAACTCTATGACATTGAGCAACAG
CAGATAAGGAACGCCCTGGAAAACATCAGAAAGGAGATGAAGTTGCTGGAGCAGGCAGGT
TCTCTGAAAGGCTCCCTGAGTGTGGAAGAGCAGCTGTCACTCATCAGTGGTTGTCCCAAT
ATCCAAGAAGCAGTAGAGGGTGCCATGCACATTCAGGAATGTGTTCCAGAAGATCTAGAA
CTGAAGAAGAAGATTTTTGCTCAGTTAGATTCCATCATTGATGATCGAGTGATCTTAAGC
AGTTCCACTTCTTGTCTCATGCCTTCCAAGTTGTTTGCTGGCTTGGTCCATGTGAAGCAA
TGCATCGTGGCTCATCCTGTGAATCCGCCATACTACATCCCGCTGGTTGAGCTGGTCCCC
CACCCGGAGACGGCCCCTACGACAGTGGACAGAACCCACGCCCTGATGAAGAAGATTGGA
CAGTGCCCCATGCGAGTCCAGAAGGAGGTGGCCGGCTTCGTTCTGAACCGCCTGCAATAT
GCAATCATCAGCGAGGCCTGGCGGCTAGTGGAGGAAGGAATCGTGTCTCCTAGTGACCTG
GACCTTGTCATGTCAGAAGGGTTGGGCATGCGGTATGCATTCATTGGACCCCTGGAAACC
ATGCATCTCAATGCAGAAGGTATGTTAAGCTACTGCGACAGATACAGCGAAGGCATAAAA
CATGTCCTACAGACTTTTGGACCCATTCCAGAGTTTTCCAGGGCCACTGCTGAGAAGGTT
AACCAGGACATGTGCATGAAGGTCCCTGATGACCCGGAGCACTTAGCTGCCAGGAGGCAG
TGGAGGGACGAGTGCCTCATGAGACTCGCCAAGTTGAAGAGTCAAGTGCAGCCCCAGTGA
|
Protein Properties |
Number of Residues
| 319 |
Molecular Weight
| 35418.91 |
Theoretical pI
| 6.175 |
Pfam Domain Function
|
|
Signals
|
Not Available
|
Transmembrane Regions
|
Not Available
|
Protein Sequence
|
>Lambda-crystallin homolog
MASSAAGCVVIVGSGVIGRSWAMLFASGGFQVKLYDIEQQQIRNALENIRKEMKLLEQAG
SLKGSLSVEEQLSLISGCPNIQEAVEGAMHIQECVPEDLELKKKIFAQLDSIIDDRVILS
SSTSCLMPSKLFAGLVHVKQCIVAHPVNPPYYIPLVELVPHPETAPTTVDRTHALMKKIG
QCPMRVQKEVAGFVLNRLQYAIISEAWRLVEEGIVSPSDLDLVMSEGLGMRYAFIGPLET
MHLNAEGMLSYCDRYSEGIKHVLQTFGPIPEFSRATAEKVNQDMCMKVPDDPEHLAARRQ
WRDECLMRLAKLKSQVQPQ
|
External Links |
GenBank ID Protein
| 115430219 |
UniProtKB/Swiss-Prot ID
| Q9Y2S2 |
UniProtKB/Swiss-Prot Entry Name
| CRYL1_HUMAN |
PDB IDs
|
|
GenBank Gene ID
| NM_015974.2 |
GeneCard ID
| CRYL1 |
GenAtlas ID
| CRYL1 |
HGNC ID
| HGNC:18246 |
References |
General References
| Not Available |