| Identification |
|---|
| HMDB Protein ID
| CDBP04982 |
| Secondary Accession Numbers
| Not Available |
| Name
| Serine incorporator 4 |
| Description
| Not Available |
| Synonyms
|
Not Available
|
| Gene Name
| SERINC4 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in phospholipid biosynthetic process |
| Specific Function
| Incorporates a polar amino acid serine into membranes and facilitates the synthesis of two serine-derived lipids, phosphatidylserine and sphingolipids |
| GO Classification
|
| Component |
| membrane |
| cell part |
|
| Cellular Location
|
- Membrane
- Multi-pass membrane protein (Potential)
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 15q15.3 |
| SNPs
| SERINC4 |
| Gene Sequence
|
Not Available
|
| Protein Properties |
|---|
| Number of Residues
| 518 |
| Molecular Weight
| 56869.4 |
| Theoretical pI
| 8.39 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
- ["59-79", "122-142", "153-173", "184-204", "222-242", "259-279", "286-306", "338-357", "427-447", "470-490"]
|
| Protein Sequence
|
>Serine incorporator 4
MVGAKAGPSPGTSLGLAQQHSGGSSVLVKSPFCQVCCCGPAPCASCCHSRWPSLTASTCS
RLFYILLHVGASAICCLLLSRTVVERVWGKTHRIQMPSGLCAHLFGLSDCPVLSGSGAVY
RVCAGTATFHLLQAVLLVHLHSPTSPRAQLHNSFWLLKLLFLLGLCAIAFCIPDEHLFPA
WHYIGICGGFAFILLQLVLITAFAHSWNKNWQTGAAQDCSWFLAVLLATLGFYSMAGVGA
VLLFHYYTHPAGCLLNKMLLSLHLCFCGLISFLSIAPCIRLKQPRSGLLQASVISCYIMY
LTFSALSSRPPERVILQGQNHTLCLPGLSKMEPQTPDISLAMLSASIMYACVLFACNEAS
YLAEVFGPLWIVKVYSYEFQKPSLCFCCPETVEADKGQRGGAARPADQETPPAPPVQVQH
LSYNYSAFHFVFFLASLYVMVTLTNWFSYEGAELEKTFIKGSWATFWVKVASCWACVLLY
LGLLLAPLCWPPTQKPQPLILRRRRHRIISPDNKYPPV
|
| External Links |
|---|
| GenBank ID Protein
| 75677608 |
| UniProtKB/Swiss-Prot ID
| A6NH21 |
| UniProtKB/Swiss-Prot Entry Name
| SERC4_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| Not Available |
| GeneCard ID
| SERINC4 |
| GenAtlas ID
| SERINC4 |
| HGNC ID
| HGNC:32237 |
| References |
|---|
| General References
| Not Available |