| Identification |
|---|
| HMDB Protein ID
| CDBP04975 |
| Secondary Accession Numbers
| Not Available |
| Name
| Apolipoprotein C-II |
| Description
| Not Available |
| Synonyms
|
- Apo-CII
- ApoC-II
- Apolipoprotein C2
|
| Gene Name
| APOC2 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in enzyme activator activity |
| Specific Function
| Component of the very low density lipoprotein (VLDL) fraction in plasma, and is an activator of several triacylglycerol lipases. The association of APOC2 with plasma chylomicrons, VLDL, and HDL is reversible, a function of the secretion and catabolism of triglyceride-rich lipoproteins, and changes rapidly |
| GO Classification
|
| Component |
| macromolecular complex |
| chylomicron |
| protein-lipid complex |
| plasma lipoprotein particle |
| Function |
| enzyme activator activity |
| enzyme regulator activity |
| Process |
| metabolic process |
| primary metabolic process |
| establishment of localization |
| transport |
| lipid metabolic process |
| lipid transport |
|
| Cellular Location
|
- Secreted
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 19q13.2 |
| SNPs
| APOC2 |
| Gene Sequence
|
>306 bp
ATGGGCACACGACTCCTCCCAGCTCTGTTTCTTGTCCTCCTGGTATTGGGATTTGAGGTC
CAGGGGACCCAACAGCCCCAGCAAGATGAGATGCCTAGCCCGACCTTCCTCACCCAGGTG
AAGGAATCTCTCTCCAGTTACTGGGAGTCAGCAAAGACAGCCGCCCAGAACCTGTACGAG
AAGACATACCTGCCCGCTGTAGATGAGAAACTCAGGGACTTGTACAGCAAAAGCACAGCA
GCCATGAGCACTTACACAGGCATTTTTACTGACCAAGTTCTTTCTGTGCTGAAGGGAGAG
GAGTAA
|
| Protein Properties |
|---|
| Number of Residues
| 101 |
| Molecular Weight
| 11283.8 |
| Theoretical pI
| 4.36 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Apolipoprotein C-II
MGTRLLPALFLVLLVLGFEVQGTQQPQQDEMPSPTFLTQVKESLSSYWESAKTAAQNLYE
KTYLPAVDEKLRDLYSKSTAAMSTYTGIFTDQVLSVLKGEE
|
| External Links |
|---|
| GenBank ID Protein
| 32130518 |
| UniProtKB/Swiss-Prot ID
| P02655 |
| UniProtKB/Swiss-Prot Entry Name
| APOC2_HUMAN |
| PDB IDs
|
|
| GenBank Gene ID
| NM_000483.3 |
| GeneCard ID
| APOC2 |
| GenAtlas ID
| APOC2 |
| HGNC ID
| HGNC:609 |
| References |
|---|
| General References
| Not Available |