Cannabis Compound Database: Showing Protein Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 (CDBP04968)

Identification Biological properties Gene properties Protein properties External links References XML Show 1 compounds

Identification

HMDB Protein ID

CDBP04968

Secondary Accession Numbers

Not Available

Name

Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2

Description

Not Available

Synonyms

Centaurin-beta-2
Cnt-b2

Gene Name

ACAP2

Protein Type

Metal Binding

Biological Properties

General Function

Involved in ARF GTPase activator activity

Specific Function

GTPase-activating protein (GAP) for ADP ribosylation factor 6 (ARF6)

GO Classification

Function
small gtpase regulator activity
ion binding
cation binding
metal ion binding
binding
transition metal ion binding
zinc ion binding
enzyme regulator activity
arf gtpase activator activity
nucleoside-triphosphatase regulator activity
gtpase regulator activity
Process
regulation of metabolic process
regulation of cellular metabolic process
regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
regulation of nucleotide metabolic process
regulation of nucleotide catabolic process
regulation of purine nucleotide catabolic process
regulation of gtp catabolic process
regulation of gtpase activity
regulation of ras gtpase activity
regulation of arf gtpase activity
biological regulation
regulation of biological process

Cellular Location

Not Available

Pathways

Not Available

Gene Properties

Chromosome Location

Chromosome:3

Locus

3q29

SNPs

ACAP2

Gene Sequence

>2337 bp
ATGAAGATGACTGGGGATTTCGAGGAGTGTCTGAAGGACTCGCCCCGCTTCAGGGCAGCT
TTGGAAGAAGTAGAAGGTGATGTGGCAGAATTGGAACTAAAACTTGATAAGCTTGTGAAA
CTTGGGATTGCAATGATTGATACTGGAAAAGCCTTTTGTGTTGCAAATAAACAGTTCATG
AATGGGATTCGAGACCTGGCCCAGTATTCTAGTAATGATGCTGTCGTTGAGACAAGTTTG
ACCAAGTTTTCTGACAGTCTTCAAGAAATGATAAATTTTCACACAATCCTGTTGCCAAAC
TCAGAGATCAATTTAAGGCACAGCTTCAGTAACTTTGTTAAAGAAGATCTTAGAAAATTC
AAAGATGCCAAGAAGCAATTTGAAAAAGTCAGTGAAGAAAAAGAAAATGCGTTAGTAAAA
AATGCCCAAGTACAAAGAAACAAACAACATGAAGTTGAAGAAGCCACCAACATTCTGACA
GCAACAAGAAAATGTTTCCGACACATAGCCCTCGATTATGTGCTTCAGATTAATGTTCTT
CAATCAAAAAGGAGATCAGAAATCCTAAAATCAATGTTGTCATTTATGTATGCCCATTTG
GCCTTCTTTCATCAAGGATATGATCTGTTTAGTGAACTTGGACCCTACATGAAGGATCTT
GGTGCACAGTTGGATCGACTGGTTGGGGATGCAGCAAAGGAGAAAAGAGAAATGGAGCAA
AAACATTCCACCATTCAACAAAAGGATTTCTCCAGGGATGATTCTAAATTAAAATATAAC
GTAGATGCTGCAAATGGCATAGTTATGGAAGGATATCTGTTCAAACGAGCCAGCAATGCC
TTCAAAACTTGGAACAGGCGCTGGTTTTCAATACAAAATAATCAGGTGGTTTACCAGAAA
AAATTTAAGGATAATCCGACTGTGGTAGTTGAAGACCTCAGGCTTTGCACAGTGAAACAT
TGTGAAGACATAGAGCGACGATTCTGCTTTGAGGTGGTCTCGCCAACAAAAAGTTGTATG
CTCCAGGCAGATTCCGAAAAGCTGCGCCAGGCATGGATTAAGGCTGTTCAGACCAGTATT
GCTACTGCTTATAGAGAGAAGGGTGATGAATCAGAGAAGCTGGATAAGAAATCATCTCCA
TCCACAGGAAGCCTAGATTCTGGAAATGAGTCCAAAGAGAAATTATTGAAAGGAGAAAGT
GCGCTTCAGCGGGTCCAGTGTATCCCTGGCAATGCCAGCTGTTGTGACTGTGGCCTGGCA
GATCCACGGTGGGCCAGCATCAACCTGGGCATCACCTTGTGTATCGAGTGCTCCGGAATT
CACCGGAGCCTTGGGGTTCATTTTTCAAAAGTACGATCTTTAACTTTAGACACCTGGGAG
CCAGAACTTTTAAAGCTTATGTGTGAGTTGGGGAATGATGTTATAAATCGAGTTTATGAA
GCTAATGTGGAAAAAATGGGAATAAAGAAACCCCAACCAGGACAAAGACAGGAGAAGGAG
GCATATATCAGAGCAAAATATGTGGAGAGGAAATTTGTGGATAAATATTCTATATCATTA
TCACCTCCTGAGCAGCAAAAAAAGTTTGTCTCTAAAAGTTCTGAAGAAAAGAGGCTGAGC
ATTTCTAAATTTGGGCCAGGGGACCAAGTCAGAGCATCTGCCCAAAGTTCAGTCAGAAGT
AATGACAGTGGAATTCAGCAGAGCTCTGATGATGGAAGAGAATCTTTACCCTCCACGGTG
TCAGCCAATAGTTTATATGAGCCTGAAGGAGAAAGGCAAGATTCTTCTATGTTTCTTGAC
TCGAAACATCTTAATCCAGGACTTCAGCTTTATAGGGCGTCATATGAAAAAAACCTTCCT
AAAATGGCTGAGGCTTTGGCTCATGGTGCAGACGTGAACTGGGCCAATTCAGAGGAAAAC
AAAGCGACACCACTTATTCAGGCTGTATTAGGGGGCTCTTTGGTGACGTGTGAGTTCCTC
CTACAGAATGGTGCTAATGTCAACCAAAGAGATGTCCAAGGGCGGGGACCATTGCACCAT
GCCACCGTCTTAGGGCACACAGGGCAGGTATGTTTATTCCTAAAACGAGGTGCCAATCAA
CATGCCACTGATGAAGAAGGGAAAGACCCTTTGAGCATAGCTGTGGAAGCAGCCAATGCT
GATATAGTCACCTTGTTACGTTTAGCAAGAATGAATGAAGAGATGCGGGAATCAGAAGGA
CTTTATGGACAGCCAGGTGATGAAACTTATCAGGACATATTTCGTGATTTTTCCCAAATG
GCATCCAATAATCCAGAGAAACTAAATCGTTTCCAGCAAGATTCACAGAAATTCTGA

Protein Properties

Number of Residues

778

Molecular Weight

88027.9

Theoretical pI

6.78

Pfam Domain Function

Ank (PF00023 )
PH (PF00169 )
ArfGap (PF01412 )

Signals

["None"]

Transmembrane Regions

["None"]

Protein Sequence

>Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2
MKMTVDFEECLKDSPRFRAALEEVEGDVAELELKLDKLVKLCIAMIDTGKAFCVANKQFM
NGIRDLAQYSSNDAVVETSLTKFSDSLQEMINFHTILFDQTQRSIKAQLQNFVKEDLRKF
KDAKKQFEKVSEEKENALVKNAQVQRNKQHEVEEATNILTATRKCFRHIALDYVLQINVL
QSKRRSEILKSMLSFMYAHLAFFHQGYDLFSELGPYMKDLGAQLDRLVVDAAKEKREMEQ
KHSTIQQKDFSSDDSKLEYNVDAANGIVMEGYLFKRASNAFKTWNRRWFSIQNNQLVYQK
KFKDNPTVVVEDLRLCTVKHCEDIERRFCFEVVSPTKSCMLQADSEKLRQAWIKAVQTSI
ATAYREKGDESEKLDKKSSPSTGSLDSGNESKEKLLKGESALQRVQCIPGNASCCDCGLA
DPRWASINLGITLCIECSGIHRSLGVHFSKVRSLTLDTWEPELLKLMCELGNDVINRVYE
ANVEKMGIKKPQPGQRQEKEAYIRAKYVERKFVDKYSISLSPPEQQKKFVSKSSEEKRLS
ISKFGPGDQVRASAQSSVRSNDSGIQQSSDDGRESLPSTVSANSLYEPEGERQDSSMFLD
SKHLNPGLQLYRASYEKNLPKMAEALAHGADVNWANSEENKATPLIQAVLGGSLVTCEFL
LQNGANVNQRDVQGRGPLHHATVLGHTGQVCLFLKRGANQHATDEEGKDPLSIAVEAANA
DIVTLLRLARMNEEMRESEGLYGQPGDETYQDIFRDFSQMASNNPEKLNRFQQDSQKF

External Links

GenBank ID Protein

4688902

UniProtKB/Swiss-Prot ID

Q15057

UniProtKB/Swiss-Prot Entry Name

ACAP2_HUMAN

PDB IDs

Not Available

GenBank Gene ID

AJ238248

GeneCard ID