Identification |
HMDB Protein ID
| CDBP04960 |
Secondary Accession Numbers
| Not Available |
Name
| PDZ domain-containing protein 8 |
Description
| Not Available |
Synonyms
|
- Sarcoma antigen NY-SAR-84/NY-SAR-104
|
Gene Name
| PDZD8 |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in protein binding |
Specific Function
| Not Available |
GO Classification
|
Function |
binding |
protein binding |
Process |
intracellular signaling pathway |
signaling |
signaling pathway |
|
Cellular Location
|
Not Available
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Chromosome:1 |
Locus
| 10q26.12 |
SNPs
| PDZD8 |
Gene Sequence
|
>3465 bp
ATGGGGCTGCTGCTCATGATCCTGGCGTCGGCCGTGCTGGGTTCCTTCCTCACGCTCCTC
GCCCAGTTCTTCCTGCTGTACCGCAGACAGCCCGAGCCGCCGGCGGACGAGGCCGCCCGC
GCGGGCGAGGGCTTCCGCTACATCAAGCCAGTGCCGGGCCTGCTCCTAAGGGAGTACCTT
TATGGCGGCGGCCGGGATGAGGAGCCCTCCGGAGCGGCCCCTGAGGGCGGCGCGACCCCC
ACCGCGGCCCCCGAGACCCCCGCCCCGCCGACGCGGGAGACTTGCTACTTCCTCAACGCC
ACCATCCTATTCCTGTTCCGGGAGTTGCGGGACACCGCGCTGACCCGCCGCTGGGTCACC
AAGAAGATCAAGGTGGAGTTCGAGGAGCTGCTGCAGACCAAGACGGCCGGGCGCCTGCTG
GAGGGGCTGAGCCTGCGGGACGTGTTCCTGGGCGAGACGGTGCCCTTCATCAAGACCATC
CGGCTCGTGCGGCCAGTCGTGCCCTCGGCCACCGGGGAGCCCGATGGCCCTGAAGGGGAG
GCGCTGCCCGCCGCCTGCCCCGAGGAGCTGGCCTTCGAGGCGGAGGTGGAGTACAACGGG
GGCTTCCACCTGGCCATCGACGTGGACCTGGTCTTCGGCAAGTCCGCCTACTTGTTTGTC
AAGCTGTCCCGCGTGGTGGGAAGGCTGCGCTTGGTCTTTACGCGCGTGCCCTTCACCCAC
TGGTTCTTCTCCTTCGTGGAAGACCCGCTGATCGACTTCGAGGTGCGCTCCCAGTTTGAA
GGGCGGCCCATGCCCCAGCTCACCTCCATCATCGTCAACCAGCTCAAGAAGATCATCAAG
CGCAAGCACACCCTACCGAATTACAAGATCAGGTTTAAGCCGTTTTTTCCATACCAGACC
TTGCAAGGATTTGAAGAAGATGAAGAGCATATCCATATACAACAATGGGCACTTACTGAA
GGCCGTCTTAAAGTTACGTTGTTAGAATGTAGCAGGTTACTCATTTTTGGATCCTATGAC
AGAGAGGCAAATGTTCATTGTACACTTGAGTTAAGCAGTAGTGTTTGGGAAGAAAAACAG
AGGAGTTCTATTAAGACGGTTGAATTAATAAAAGGAAATTTACAAAGTGTTGGACTTACA
CTTCGTCTTGTCCAGTCAACTGATGGGTATGCTGGGCACGTCATCATTGAAACTGTGGCT
CCAAACTCGCCTGCTGCAATTGCAGATCTTCAGCGGGGAGATCGACTTATCGCCATTGGA
GGTGTGAAAATCACATCAACACTGCAAGTGTTGAAGCTTATCAAGCAGGCTGGTGACCGA
GTCCTGGTGTACTATGAAAGGCCTGTTGGCCAGAGTAATCAAGGTGCAGTGCTGCAAGAT
AACTTTGGCCAGTTGGAAGAAAACTTTTTGTCAAGCTCATGCCAATCGGGTTATGAAGAG
GAAGCTGCCGGGTTGACAGTAGATACTGAAAGTAGAGAGCTGGATTCTGAATTTGAAGAC
TTGGCAAGTGATGTCAGAGCACAAAATGAGTTCAAAGATGAGGCACAATCATTAAGTCAT
AGTCCCAAACGTGTTCCAACAACACTTTCTATTAAACCCCTTGGAGCTATATCACCAGTT
TTAAACCGTAAATTAGCTGTAGGAAGTCACCCACTACCACCGAAAATTCAGTCCAAAGAT
GGAAATAAACCTCCACCCCTAAAAACTTCTGAGATAACAGACCCAGCACAAGTGTCAAAA
CCAACCCAAGGATCTGCTTTCAAACCACCTGTGCCACCACGACCACAAGCGAAAGTTCCT
TTGCCTTCCGCCGATGCTCCAAATCAGGCAGAACCAGATGTTCTCGTTGAAAAGCCAGAG
AAGGTGGTGCCACCTCCTCTTGTAGATAAATCTGCTGAAAAGCAAGCAAAAAATGTGGAT
GCCATAGACGATGCAGCTGCACCTAAGCAATTTTTAGCAAAGCAAGAAGTGGCCAAAGAT
GTCACTTCAGAAACTTCCTGCCCTACTAAGGACAGTTCGGACGACCGTCAAACATGGGAA
TCATCAGAAATTCTTTATCGTAATAAGCTAGGAAAATGGACAAGAACCAGAGCATCCTGT
TTGTTTGACATAGAAGCCTGTCACAGGTACTTAAACATTGCATTGTGGTGCAGGGATCCT
TTCAAGTTGGGAGGTCTCATCTGTTTGGGGCATGTTAGTTTAAAACTTGAAGATGTGGCT
TTAGGATGCCTAGCTACATCAAACACGGAATACCTTTCCAAATTGAGACTGGAAGCCCCC
TCACCTAAGGCTATAGTCACTAGAACCGCACTACGCAATCTGAGTATGCAAAAGGGATTC
AATGACAAATTTTGCTATGGTGACATTACTATTCACTTCAAATATTTGAAAGAAGGAGAA
TCAGACCACCATGTAGTTACTAACGTAGAAAAAGAAAAAGAACCCCATTTGGTTGAAGAA
GTTTCTGTTCTCCCTAAAGAGGAGCAATTTGTTGGACAGATGGGTTTAACAGAAAACAAA
CACAGTTTTCAGGATACTCAGTTCCAGAACCCAACATGGTGTGACTACTGTAAGAAAAAA
GTTTGGACTAAAGCAGCTTCCCAGTGTATGTTTTGTGCTTATGTTTGCCATAAAAAATGT
CAAGAAAAGTGTCTAGCTGAGACTTCTGTTTGTGGAGCAACTGATAGGCGAATAGACAGG
ACACTGAAAAACCTTAGGCTGGAAGGACAGGAAACCCTCTTAGGCCTGCCTCCTCGTGTT
GATGCTGAAGCTAGCAAGTCAGTCAATAAAACAACAGGTTTGACAAGGCATATTATCAAT
ACTAGTTCTCGTTTATTAAATTTGCGTCAAGTCTCTAAAACTCGCCTTTCTGAACCAGGA
ACCGATCTCGTAGAACCTTCACCAAAACACACACCCAACACGTCAGACAACGAAGGCAGT
GACACGGAGGTCTGTGGTCCAAACAGTCCTTCTAAACGGGGAAACAGCACAGGAATAAAG
TTAGTGAGAAAAGAGGGTGGTCTGGATGACAGTGTTTTCATTGCAGTTAAAGAAATTGGT
CGTGATCTGTACAGGGGCTTGCCTACAGAGGAAAGGATCCAGAAACTAGAGTTCATGTTG
GATAAGCTACAGAATGAAATTGATCAGGAGTTGGAACACAATAATTCCCTTGTTAGAGAA
GAAAAAGAGACAACTGATACAAGGAAAAAATCACTTCTTTCTGCTGCCTTAGCTAAATCA
GGTGAAAGGCTACAAGCTCTAACACTTCTTATGATTCACTACAGAGCAGGCATTGAAGAT
ATAGAAACTTTAGAAAGTCTGTCTTTAGACCAGCACTCCAAAAAAATAAGCAAGTACACA
GATGATACAGAAGAAGACCTTGATAATGAAATAAGCCAACTAATAGACTCTCAGCCATTC
AGCAGCATATCAGATGACTTATTTGGCCCATCCGAGTCTGTGTAG
|
Protein Properties |
Number of Residues
| 1154 |
Molecular Weight
| 128562.1 |
Theoretical pI
| 5.95 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
|
Protein Sequence
|
>PDZ domain-containing protein 8
MGLLLMILASAVLGSFLTLLAQFFLLYRRQPEPPADEAARAGEGFRYIKPVPGLLLREYL
YGGGRDEEPSGAAPEGGATPTAAPETPAPPTRETCYFLNATILFLFRELRDTALTRRWVT
KKIKVEFEELLQTKTAGRLLEGLSLRDVFLGETVPFIKTIRLVRPVVPSATGEPDGPEGE
ALPAACPEELAFEAEVEYNGGFHLAIDVDLVFGKSAYLFVKLSRVVGRLRLVFTRVPFTH
WFFSFVEDPLIDFEVRSQFEGRPMPQLTSIIVNQLKKIIKRKHTLPNYKIRFKPFFPYQT
LQGFEEDEEHIHIQQWALTEGRLKVTLLECSRLLIFGSYDREANVHCTLELSSSVWEEKQ
RSSIKTVELIKGNLQSVGLTLRLVQSTDGYAGHVIIETVAPNSPAAIADLQRGDRLIAIG
GVKITSTLQVLKLIKQAGDRVLVYYERPVGQSNQGAVLQDNFGQLEENFLSSSCQSGYEE
EAAGLTVDTESRELDSEFEDLASDVRAQNEFKDEAQSLSHSPKRVPTTLSIKPLGAISPV
LNRKLAVGSHPLPPKIQSKDGNKPPPLKTSEITDPAQVSKPTQGSAFKPPVPPRPQAKVP
LPSADAPNQAEPDVLVEKPEKVVPPPLVDKSAEKQAKNVDAIDDAAAPKQFLAKQEVAKD
VTSETSCPTKDSSDDRQTWESSEILYRNKLGKWTRTRASCLFDIEACHRYLNIALWCRDP
FKLGGLICLGHVSLKLEDVALGCLATSNTEYLSKLRLEAPSPKAIVTRTALRNLSMQKGF
NDKFCYGDITIHFKYLKEGESDHHVVTNVEKEKEPHLVEEVSVLPKEEQFVGQMGLTENK
HSFQDTQFQNPTWCDYCKKKVWTKAASQCMFCAYVCHKKCQEKCLAETSVCGATDRRIDR
TLKNLRLEGQETLLGLPPRVDAEASKSVNKTTGLTRHIINTSSRLLNLRQVSKTRLSEPG
TDLVEPSPKHTPNTSDNEGSDTEVCGPNSPSKRGNSTGIKLVRKEGGLDDSVFIAVKEIG
RDLYRGLPTEERIQKLEFMLDKLQNEIDQELEHNNSLVREEKETTDTRKKSLLSAALAKS
GERLQALTLLMIHYRAGIEDIETLESLSLDQHSKKISKYTDDTEEDLDNEISQLIDSQPF
SSISDDLFGPSESV
|
External Links |
GenBank ID Protein
| 29789403 |
UniProtKB/Swiss-Prot ID
| Q8NEN9 |
UniProtKB/Swiss-Prot Entry Name
| PDZD8_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| NM_173791.3 |
GeneCard ID
| PDZD8 |
GenAtlas ID
| PDZD8 |
HGNC ID
| HGNC:26974 |
References |
General References
| Not Available |