| Identification |
|---|
| HMDB Protein ID
| CDBP04955 |
| Secondary Accession Numbers
| Not Available |
| Name
| Unc-13 homolog B (C. elegans) |
| Description
| Not Available |
| Synonyms
|
Not Available
|
| Gene Name
| UNC13B |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in intracellular signaling pathway |
| Specific Function
| Not Available |
| GO Classification
|
| Process |
| signaling |
| signaling pathway |
| intracellular signaling pathway |
|
| Cellular Location
|
Not Available
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:9 |
| Locus
| 9p13.3 |
| SNPs
| UNC13B |
| Gene Sequence
|
>4869 bp
ATGTCACTGCTCTGCGTGCGCGTTAAAAGGGCCAAATTCCAGGGTTCACCAGATAAATTT
AACACATATGTGACCCTGAAAGTACAGAATGTGAAGAGCACAACTGTAGCAGTTCGTGGT
GATCAGCCTTCCTGGGAACAGGATTTCATGTTTGAGATTAGTCGCCTGGACCTGGGTCTA
AGTGTGGAGGTATGGAACAAAGGACTGATCTGGGACACCATGGTGGGGACTGTGTGGATT
GCGCTGAAGACTATTCGTCAGTCGGATGAGGAAGGGCCTGGGGAATGGTCCACATTAGAG
GCAGAGACGTTAATGAAAGACGATGAGATCTGTGGAACTAGAAACCCAACTCCTCATAAA
ATTTTGCTTGATACAAGATTTGAGTTGCCTTTTGATATCCCAGAGGAGGAAGCCAGATAT
TGGACCTACAAATGGGAGCAAATCAATGCCTTGGGAGCTGACAATGAGTATTCTAGTCAA
GAAGAAAGCCAGAGGAAGCCATTGCCCACTGCTGCCGCCCAGTGTTGTCACTGGACCTAT
TTGGGCTGGGGAGAACAACAGACTTTTGAAGACCCTGATAGTGCCGTCGATGACCGAGAT
AGTGACTATCGCAGTGAGACCAGCAACAGCTTCCCACCTCCTTACCATACAGCTTCCCAG
CCCAACGCTTCTGTGCACCAGTTCCCTGTGCCGGTGCGATCGCCACAGCAGCTGCTACTT
CAAGGCAGTTCCCGGGACTCTTGTAATGACTCTATGCAAAGTTATGACCTTGATTATCCA
GAGCGGCGGGCTATCAGCCCCACCAGCAGCAGTAGGTATGGCTCCTCCTGTAATGTGAGT
CAAGGAAGCTCTCAGCTAAGTGAACTAGACCAGTATCACGAACAAGATGACGACCATCGG
GAGACGGACTCGATTCATTCTTGCCACAGCTCTCACAGCCTGTCCAGAGATGGCCAAGCA
GGTTTTGGAGAACAAGAGAAACCCTTGGAGGTGACAGGTCAAGCAGAGAAGGAGGCAGCA
TGTGAACCCAAGGAGATGAAAGAAGATGCCACAACCCACCCTCCCCCAGATCTGGTGCTG
CAAAAAGACCACTTCCTAGGTCCCCAGGAGAGTTTTCCTGAGGAGAATGCATCTTCACCA
TTTACCCAAGCCAGAGCACATTGGATCCGAGCAGTTACCAAGGTTCGACTCCAGCTGCAG
GAGATTCCAGATGATGGTGACCCCTCTCTGCCTCAGTGGCTCCCGGAAGGGCCAGCCGGA
GGGCTCTATGGCATTGACAGCATGCCAGATTTACGCAGAAAGAAGCCACTGCCACTTGTC
AGTGATCTGTCACTGGTCCAGTCTCGGAAGGCAGGAATCACTTCTGCAATGGCTACACGC
ACTTCTCTTAAGGACGAAGAGCTGAAATCCCACGTGTATAAGAAAACCCTGCAGGCCTTA
ATCTACCCCATTTCGTGCACCACTCCTCATAACTTTGAGGTCTGGACGGCCACTACCCCA
ACCTACTGCTATGAGTGTGAAGGCCTGCTCTGGGGCATTGCCCGGCAGGGCATGCGCTGC
AGCGAATGTGGAGTCAAGTGCCATGAGAAGTGCCAGGATCTGCTCAATGCTGACTGCCTG
CAGCGGGCTGCAGAAAAGAGCTGTAAACATGGAGCTGAGGACCGGACCCAGAACATTATC
ATGGCCATGAAGGACCGCATGAAGATCCGAGAGCGAAATAAGCCAGAGATCTTTGAAGTT
ATCCGGGACGTCTTCACAGTGAACAAAGCTGCCCATGTGCAGCAGATGAAAACAGTGAAG
CAGAGTGTACTGGATGGCACCTCCAAATGGTCAGCCAAGATCACCATTACTGTGGTGTGT
GCCCAGGGCCTACAAGCCAAGGACAAAACAGGATCCAGTGACCCTTACGTGACTGTGCAA
GTCAGCAAAACTAAGAAGCGTACCAAGACCATTTTTGGAAACTTGAATCCTGTTTGGGAG
GAGAAGTTCCATTTTGAGTGCCACAACTCCTCTGACCGCATTAAGGTGCGTGTATGGGAT
GAGGATGATGACATCAAGTCAAGAGTAAAGCAACGCCTAAAGCGAGAGTCTGATGATTTC
CTTGGCCAAACCATCATTGAGGTTCGGACCCTAAGTGGCGAGATGGACGTCTGGTACAAC
TTGGAGAAGAGGACAGACAAATCAGCCGTCTCAGGGGCTATCCGACTACAAATCAGTGTG
GAGATCAAGGGGGAGGAGAAAGTAGCCCCATACCACGTGCAGTATACATGTCTCCATGAG
AATCTTTTCCATTACCTCACAGACATTCAGGGCAGTGGAGGAGTCCGCATCCCTGAAGCT
CGAGGAGACGATGCCTGGAAGGTGTACTTTGATGAGACAGCCCAAGAAATTGTGGATGAA
TTTGCCATGCGTTATGGCATTGAGTCCATATATCAGGCCATGACGCACTTTGCATGTTTA
TCATCCAAGTACATGTGTCCTGGTGTGCCAGCAGTGATGAGCACCTTACTGGCCAACATC
AACGCCTACTATGCCCACACAACTGCCTCTACCAATGTCTCTGCATCTGATCGCTTTGCA
GCCTCCAACTTTGGGAAAGAGAGATTTGTAAAACTGCTGGACCAGCTACACAACTCACTG
AGGATCGACCTCTCTACATACAGGAATAATTTCCCTGCTGGGAGTCCTGAACGGCTTCAG
GACTTAAAATCCACAGTGGATTTGCTGACCAGCATTACTTTCTTCAGAATGAAGGTACAA
GAACTGCAAAGCCCTCCAAGAGCCAGCCAGGTGGTAAAGGATTGTGTGAAGGCCTGTTTG
AACTCCACATATGAATATATCTTCAACAACTGCCACGACTTATACAGCCGCCAGTACCAG
CTGAAGCAGGAGCTACCTCCAGAGGAACAAGGGCCCAGCATTCGGAACCTGGATTTCTGG
CCCAAGCTCATCACACTCATCGTGTCAATCATAGAGGAAGATAAGAATTCCTACACACCT
GTTCTGAACCAGTTTCCTCAGGAGTTGAATGTGGGAAAAGTCAGCGCAGAAGTGATGTGG
CATTTGTTTGCCCAAGACATGAAATATGCATTGGAGGAGCATGAGAAAGACCACCTGTGT
AAAAGTGCTGACTACATGAACCTGCACTTCAAGGTGAAGTGGCTCCACAATGAATACGTG
CGGGATCTGCCTGTCCTCCAGGGGCAGGTGCCTGAGTACCCAGCGTGGTTTGAGCAGTTC
GTGCTACAATGGCTGGATGAGAATGAGGATGTATCCCTGGAATTCCTGCGTGGGGCCCTG
GAACGAGATAAGAAGGATGGATTCCAGCAGACATCAGAGCATGCACTCTTTTCCTGCTCT
GTGGTGGATGTCTTCACACAACTCAATCAGAGCTTTGAGATCATCCGGAAGCTGGAATGC
CCAGACCCCAGCATCCTTGCCCACTACATGAGGAGGTTTGCTAAGACCATCGGGAAGGTG
CTGATGCAGTATGCAGACATCTTGTCAAAGGACTTCCCAGCCTATTGCACAAAGGAGAAA
CTGCCCTGCATCCTGATGAACAACGTGCAGCAACTGAGGGTCCAGCTGGAGAAAATGTTT
GAGGCCATGGGAGGCAAGGAGCTGGACCTTGAAGCTGCAGACAGTCTGAAGGAGCTGCAG
GTGAAACTGAATACGGTTCTGGATGAGCTCAGCATGGTGTTTGGAAACAGTTTCCAGGTA
CGGATTGATGAGTGTGTTCGACAAATGGCCGACATCCTGGGCCAGGTTCGGGGCACAGGG
AATGCATCTCCAGACGCCAGGGCCTCAGCGGCTCAGGATGCAGATAGCGTACTCCGGCCT
CTCATGGACTTCCTGGATGGCAACCTCACCCTCTTTGCCACTGTGTGTGAGAAGACGGTT
CTGAAGCGTGTACTGAAGGAGCTCTGGCGCGTGGTGATGAACACAATGGAGAGGATGATT
GTTCTGCCCCCACTCACTGACCAGACGGGCACCCAGCTGATCTTCACTGCTGCCAAGGAG
CTGAGCCATCTTTCCAAACTCAAGGATCACATGGTACGAGAGGAAACACGGAATCTCACT
CCAAAGCAGTGTGCAGTCCTTGACCTCGCCCTGGACACCATCAAGCAATACTTCCATGCA
GGAGGCAATGGGCTGAAGAAAACCTTCCTGGAGAAGAGCCCAGATCTGCAGTCTCTACGC
TATGCCCTGTCTCTGTACACACAGACTACTGACACTCTCATCAAGACCTTTGTGCGCTCG
CAGACCACCCAAGTGCATGATGGGAAAGGTATTAGATTTACTGCTAATGAGGACATTCGT
CCGGAAAAGGGGTCTGGTGTGGACGATCCTGTGGGAGAAGTCTCTATTCAGGTGGACTTG
TTTACACACCCTGGTACTGGGGAGCACAAGGTCACAGTGAAAGTGGTGGCTGCCAATGAC
CTCAAGTGGCAGACAGCGGGTATGTTCCGGCCTTTCGTGGAGGTGACTATGGTTGGCCCA
CACCAAAGTGATAAGAAGAGGAAGTTCACAACCAAATCCAAAAGCAACAACTGGGCCCCC
AAGTACAATGAGACATTCCACTTCCTCCTGGGAAATGAGGAGGGGCCCGAGTCCTATGAG
TTGCAGATATGCGTGAAGGATTACTGCTTTGCCCGGGAAGATCGCGTGCTAGGGCTGGCT
GTGATGCCTCTGAGGGATGTCACAGCCAAGGGCAGCTGTGCCTGCTGGTGCCCCTTGGGC
CGGAAGATCCATATGGATGAGACAGGCCTGACCATTCTCCGGATTTTATCTCAGAGGAGC
AATGACGAGGTGGCCCGAGAATTTGTGAAACTCAAATCAGAGTCTCGTTCCACGGAGGAG
GGGAGCTGA
|
| Protein Properties |
|---|
| Number of Residues
| 1622 |
| Molecular Weight
| 184345.3 |
| Theoretical pI
| 5.88 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Unc-13 homolog B (C. elegans)
MSLLCVRVKRAKFQGSPDKFNTYVTLKVQNVKSTTVAVRGDQPSWEQDFMFEISRLDLGL
SVEVWNKGLIWDTMVGTVWIALKTIRQSDEEGPGEWSTLEAETLMKDDEICGTRNPTPHK
ILLDTRFELPFDIPEEEARYWTYKWEQINALGADNEYSSQEESQRKPLPTAAAQCCHWTY
LGWGEQQTFEDPDSAVDDRDSDYRSETSNSFPPPYHTASQPNASVHQFPVPVRSPQQLLL
QGSSRDSCNDSMQSYDLDYPERRAISPTSSSRYGSSCNVSQGSSQLSELDQYHEQDDDHR
ETDSIHSCHSSHSLSRDGQAGFGEQEKPLEVTGQAEKEAACEPKEMKEDATTHPPPDLVL
QKDHFLGPQESFPEENASSPFTQARAHWIRAVTKVRLQLQEIPDDGDPSLPQWLPEGPAG
GLYGIDSMPDLRRKKPLPLVSDLSLVQSRKAGITSAMATRTSLKDEELKSHVYKKTLQAL
IYPISCTTPHNFEVWTATTPTYCYECEGLLWGIARQGMRCSECGVKCHEKCQDLLNADCL
QRAAEKSCKHGAEDRTQNIIMAMKDRMKIRERNKPEIFEVIRDVFTVNKAAHVQQMKTVK
QSVLDGTSKWSAKITITVVCAQGLQAKDKTGSSDPYVTVQVSKTKKRTKTIFGNLNPVWE
EKFHFECHNSSDRIKVRVWDEDDDIKSRVKQRLKRESDDFLGQTIIEVRTLSGEMDVWYN
LEKRTDKSAVSGAIRLQISVEIKGEEKVAPYHVQYTCLHENLFHYLTDIQGSGGVRIPEA
RGDDAWKVYFDETAQEIVDEFAMRYGIESIYQAMTHFACLSSKYMCPGVPAVMSTLLANI
NAYYAHTTASTNVSASDRFAASNFGKERFVKLLDQLHNSLRIDLSTYRNNFPAGSPERLQ
DLKSTVDLLTSITFFRMKVQELQSPPRASQVVKDCVKACLNSTYEYIFNNCHDLYSRQYQ
LKQELPPEEQGPSIRNLDFWPKLITLIVSIIEEDKNSYTPVLNQFPQELNVGKVSAEVMW
HLFAQDMKYALEEHEKDHLCKSADYMNLHFKVKWLHNEYVRDLPVLQGQVPEYPAWFEQF
VLQWLDENEDVSLEFLRGALERDKKDGFQQTSEHALFSCSVVDVFTQLNQSFEIIRKLEC
PDPSILAHYMRRFAKTIGKVLMQYADILSKDFPAYCTKEKLPCILMNNVQQLRVQLEKMF
EAMGGKELDLEAADSLKELQVKLNTVLDELSMVFGNSFQVRIDECVRQMADILGQVRGTG
NASPDARASAAQDADSVLRPLMDFLDGNLTLFATVCEKTVLKRVLKELWRVVMNTMERMI
VLPPLTDQTGTQLIFTAAKELSHLSKLKDHMVREETRNLTPKQCAVLDLALDTIKQYFHA
GGNGLKKTFLEKSPDLQSLRYALSLYTQTTDTLIKTFVRSQTTQVHDGKGIRFTANEDIR
PEKGSGVDDPVGEVSIQVDLFTHPGTGEHKVTVKVVAANDLKWQTAGMFRPFVEVTMVGP
HQSDKKRKFTTKSKSNNWAPKYNETFHFLLGNEEGPESYELQICVKDYCFAREDRVLGLA
VMPLRDVTAKGSCACWCPLGRKIHMDETGLTILRILSQRSNDEVAREFVKLKSESRSTEE
GS
|
| External Links |
|---|
| GenBank ID Protein
| 55661547 |
| UniProtKB/Swiss-Prot ID
| B1AM27 |
| UniProtKB/Swiss-Prot Entry Name
| B1AM27_HUMAN |
| PDB IDs
|
|
| GenBank Gene ID
| AL160274 |
| GeneCard ID
| UNC13B |
| GenAtlas ID
| UNC13B |
| HGNC ID
| HGNC:12566 |
| References |
|---|
| General References
| Not Available |