| Identification |
|---|
| HMDB Protein ID
| CDBP04953 |
| Secondary Accession Numbers
| Not Available |
| Name
| Gamma-1-syntrophin |
| Description
| Not Available |
| Synonyms
|
- G1SYN
- SYN4
- Syntrophin-4
|
| Gene Name
| SNTG1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in protein binding |
| Specific Function
| Adapter protein that binds to and probably organizes the subcellular localization of a variety of proteins. May link various receptors to the actin cytoskeleton and the dystrophin glycoprotein complex. May participate in regulating the subcellular location of diacylglycerol kinase-zeta to ensure that diacylglycerol is rapidly inactivated following receptor activation |
| GO Classification
|
| Function |
| binding |
| protein binding |
|
| Cellular Location
|
- Nucleus
- Cytoplasm
- cytoskeleton
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:8 |
| Locus
| 8q11-q12 |
| SNPs
| SNTG1 |
| Gene Sequence
|
>1554 bp
ATGGATTTCAGAACCGCCTGTGAGGAGACAAAGACAGGAATTTGTTTGCTGCAGGATGGT
AACCAGGAGCCTTTCAAAGTGCGGCTGCACCTAGCCAAAGACATTTTGATGATCCAGGAA
CAGGATGTGATATGTGTGTCTGGTGAGCCTTTCTATTCTGGTGAAAGAACGGTGACCATC
AGAAGACAAACAGTAGGAGGATTTGGATTAAGCATAAAGGGAGGAGCAGAACATAACATT
CCAGTTGTCGTTTCAAAAATCTCCAAGGAACAAAGAGCGGAACTTTCAGGACTACTTTTT
ATTGGAGATGCAATTCTACAGATAAATGGCATTAATGTGAGAAAATGTAGACATGAAGAA
GTGGTTCAGGTTCTTCGGAATGCTGGAGAAGAAGTGACTCTAACAGTGTCATTTTTAAAA
AGAGCACCTGCTTTCCTCAAACTCCCATTGAATGAAGATTGTGCATGTGCTCCAAGTGAC
CAGAGCAGTGGCACCTCCTCTCCTCTCTGTGACAGTGGCTTACATCTCAACTACCATCCC
AACAATACAGACACATTATCATGCTCGTCGTGGCCGACGTCTCCAGGCTTGAGGTGGGAG
AAGCGATGGTGCGACCTCAGACTGATCCCTCTACTTCATTCGCGCTTCTCTCAGTATGTG
CCCGGCACAGATTTGAGTCGGCAGAATGCCTTTCAAGTCATTGCTGTGGATGGGGTCTGC
ACTGGGATTATTCAGTGCCTCTCTGCTGAAGACTGCGTTGACTGGCTACAAGCAATAGCA
ACTAACATTTCAAATCTCACAAAGCACAATATTAAAAAAATCAACAGAAACTTTCCTGTA
AACCAGCAGATTGTCTACATGGGCTGGTGTGAAGCCCGGGAGCAAGACCCCCTCCAGGAC
AGAGTGTACTCCCCGACCTTCCTGGCCCTGAGGGGCTCATGTCTCTACAAGTTTCTGGCA
CCTCCAGTGACCACCTGGGACTGGACGAGAGCAGAGAAAACATTCTCAGTTTATGAGATT
ATGTGCAAGATCCTCAAGGACAGTGACCTGCTGGACCGACGGAAACAGTGCTTCACCGTG
CAGTCTGAGTCTGGGGAGGACCTGTACTTCTCAGTGGAGCTGGAAAGTGACCTCGCCCAG
TGGGAAAGAGCCTTCCAGACAGCAACCTTTCTAGAAGTAGAACGGATACAGTGCAAGACC
TATGCATGTGTGCTAGAAAGTCATCTAATGGGACTCACAATTGATTTCAGCACAGGATTT
ATCTGCTTTGATGCTGCAACAAAGGCTGTCCTTTGGAGGTATAAATTCTCTCAGCTTAAA
GGTTCTTCAGATGATGGCAAGAGCAAAATCAAATTTTTGTTTCAGAATCCAGATACTAAA
CAGATTGAAGCAAAGGAGTTGGAATTTTCTAATTTATTTGCTGTTCTTCACTGCATTCAT
TCCTTCTTTGCTGCCAAGGTAGCTTGTTTGGACCCTCTATTTTTAGGCAATCAAGCTACT
GCTTCTACTGCTGCCAGCTCTGCTACCACGAGCAAAGCAAAGTATACAACTTGA
|
| Protein Properties |
|---|
| Number of Residues
| 517 |
| Molecular Weight
| 57968.7 |
| Theoretical pI
| 6.65 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Gamma-1-syntrophin
MDFRTACEETKTGICLLQDGNQEPFKVRLHLAKDILMIQEQDVICVSGEPFYSGERTVTI
RRQTVGGFGLSIKGGAEHNIPVVVSKISKEQRAELSGLLFIGDAILQINGINVRKCRHEE
VVQVLRNAGEEVTLTVSFLKRAPAFLKLPLNEDCACAPSDQSSGTSSPLCDSGLHLNYHP
NNTDTLSCSSWPTSPGLRWEKRWCDLRLIPLLHSRFSQYVPGTDLSRQNAFQVIAVDGVC
TGIIQCLSAEDCVDWLQAIATNISNLTKHNIKKINRNFPVNQQIVYMGWCEAREQDPLQD
RVYSPTFLALRGSCLYKFLAPPVTTWDWTRAEKTFSVYEIMCKILKDSDLLDRRKQCFTV
QSESGEDLYFSVELESDLAQWERAFQTATFLEVERIQCKTYACVLESHLMGLTIDFSTGF
ICFDAATKAVLWRYKFSQLKGSSDDGKSKIKFLFQNPDTKQIEAKELEFSNLFAVLHCIH
SFFAAKVACLDPLFLGNQATASTAASSATTSKAKYTT
|
| External Links |
|---|
| GenBank ID Protein
| 9507163 |
| UniProtKB/Swiss-Prot ID
| Q9NSN8 |
| UniProtKB/Swiss-Prot Entry Name
| SNTG1_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_018967.2 |
| GeneCard ID
| SNTG1 |
| GenAtlas ID
| SNTG1 |
| HGNC ID
| HGNC:13740 |
| References |
|---|
| General References
| Not Available |