| Identification |
|---|
| HMDB Protein ID
| CDBP04903 |
| Secondary Accession Numbers
| Not Available |
| Name
| Zinc fingers and homeoboxes protein 1 |
| Description
| Not Available |
| Synonyms
|
Not Available
|
| Gene Name
| ZHX1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in sequence-specific DNA binding transcription factor activity |
| Specific Function
| Acts as a transcriptional repressor |
| GO Classification
|
| Component |
| cell part |
| intracellular |
| Function |
| sequence-specific dna binding |
| sequence-specific dna binding transcription factor activity |
| ion binding |
| cation binding |
| metal ion binding |
| binding |
| transition metal ion binding |
| zinc ion binding |
| nucleic acid binding |
| dna binding |
| Process |
| biological regulation |
| regulation of biological process |
| regulation of metabolic process |
| regulation of macromolecule metabolic process |
| regulation of gene expression |
| regulation of transcription |
| regulation of transcription, dna-dependent |
|
| Cellular Location
|
- Nucleus
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:8 |
| Locus
| 8q24.13 |
| SNPs
| ZHX1 |
| Gene Sequence
|
>2622 bp
ATGGCAAGCAGGCGAAAATCAACAACACCTTGCATGGTCCTTGCCAGTGAACAAGATCCA
GACCTTGAGTTGATATCAGATTTGGATGAAGGTCCTCCTGTGCTTACACCTGTAGAAAAC
ACCAGAGCAGAGAGTATCTCAAGTGATGAAGAGGTTCATGAATCTGTGGATTCAGACAAT
CAGCAAAATAAAAAAGTTGAAGGTGGATATGAATGTAAATATTGTACTTTTCAAACTCCA
GATCTAAATATGTTTACTTTTCATGTGGATTCGGAACATCCCAATGTAGTGCTAAATTCA
TCCTATGTTTGTGTCGAATGCAATTTTCTTACCAAAAGGTATGATGCACTTTCTGAGCAT
AATCTGAAATATCACCCAGGAGAAGAGAATTTTAAGTTGACTATGGTGAAACGTAATAAC
CAGACAATCTTTGAACAAACAATAAATGATCTGACTTTTGATGGTAGTTTTGTTAAAGAG
GAGAATGCAGAGCAAGCAGAATCTACAGAAGTTTCTTCTTCGGGAATATCTATCAGTAAA
ACTCCTATCATGAAAATGATGAAAAATAAAGTGGAAAATAAACGGATTGCAGTTCATCAT
AACTCAGTTGAGGACGTTCCTGAAGAGAAAGAGAATGAAATCAAACCAGACCGTGAAGAA
ATTGTAGAAAATCCAAGTTCTTCAGCTTCTGAATCTAATACAAGTACTTCCATTGTAAAC
AGAATACATCCAAGTACTGCCAGCACGGTAGTGACACCAGCAGCAGTTCTTCCTGGATTG
GCACAGGTGATAACTGCTGTATCTGCTCAGCAGAATTCTAATTTGATTCCCAAAGTCTTA
ATCCCTGTTAATAGCATTCCCACCTACAATGCTGCATTGGATAACAATCCCCTTTTACTT
AACACCTACAACAAGTTCCCTTACCCAACAATGTCAGAAATTACAGTTCTTTCTGCTCAA
GCAAAATATACAGAGGAACAGATCAAGATATGGTTTTCAGCCCAACGTTTAAAACATGGT
GTTAGTTGGACTCCCGAGGAAGTAGAGGAGGCAAGAAGGAAACAATTCAATGGAACAGTG
CATACTGTACCTCAGACCATAACTGTTATTCCTACACACATTTCCACAGGGAGTAATGGT
TTACCATCTATTTTACAGACATGCCAAATAGTTGGTCAGCCTGGTCTGGTCCTTACTCAA
GTGGCTGGAACAAACACCTTGCCAGTTACAGCACCTATAGCCTTGACAGTGGCAGGCGTT
CCAAGTCAAAATAATATACAGAAAAGTCAGGTACCTGCTGCTCAGCCTACTGCAGAAACA
AAGCCAGCAACAGCAGCAGTTCCAACTTCTCAAAGTGTCAAACATGAAACTGCATTGGTA
AACCCTGATTCATTTGGCATTCGGGCAAAAAAGACAAAAGAGCAACTGGCAGAATTAAAA
GTTAGCTACCTTAAAAATCAGTTTCCCCATGATTCAGAAATTATCAGACTTATGAAAATA
ACAGGCCTGACGAAAGGAGAGATTAAAAAATGGTTTAGTGACACAAGGTACAACCAGAGA
AATTCAAAGAGTAATCAGTGCTTACATCTCAACAATGATTCCTCTACCACCATTATTATA
GACTCCAGTGATGAAACCACGGAATCCCCAACTGTTGGTACTGCACAGCCTAAGCAATCC
TGGAATCCTTTTCCTGACTTTACTCCCCAAAAGTTTAAAGAGAAAACTGCAGAGCAGCTT
CGTGTCCTTCAGGCAAGTTTTCTCAACAGCTCTGTACTTACAGATGAAGAATTAAATAGG
TTAAGGGCACAAACCAAACTTACCAGAAGAGAAATCGATGCTTGGTTTACAGAGAAGAAG
AAATCAAAAGCTTTAAAGGAAGAGAAAATGGAAATAGATGAAAGTAATGCAGGTAGTTCC
AAAGAAGAAGCTGGAGAAACTTCTCCTGCAGATGAATCTGGTGCACCTAAGTCAGGGAGT
ACAGGCAAGATATGTAAAAAAACACCTGAGCAGCTGCACATGCTTAAGAGTGCATTTGTC
CGGACACAGTGGCCATCACCAGAAGAGTATGACAAGTTGGCCAAAGAAAGCGGGCTTGCT
AGAACAGACATAGTTAGTTGGTTTGGGGACACCCGTTATGCTTGGAAGAATGGAAACTTG
AAATGGTACTACTACTATCAGAGCGCCAATTCAAGTAGTATGAATGGTCTGTCTTCCCTT
AGGAAAAGAGGGAGAGGGAGACCCAAAGGACGGGGAAGAGGAAGACCGCGTGGGCGGCCT
AGAGGAAGCAAAAGAATTAACAACTGGGACAGGGGACCATCACTCATAAAATTTAAAACT
GGAACTGCAATACTTAAGGATTATTACCTGAAGCACAAGTTTCTTAATGAGCAAGACCTT
GATGAACTTGTTAACAAATCACATATGGGCTATGAGCAGGTCAGAGAGTGGTTTGCAGAA
AGACAGAGAAGATCAGAATTAGGTATAGAATTATTTGAGGAAAATGAGGAGGAAGATGAA
GTTATTGATGACCAGGAAGAGGATGAAGAAGAAACAGATGATAGTGACACTTGGGAACCT
CCACGACATGTGAAACGGAAGCTGTCTAAATCAGATGACTGA
|
| Protein Properties |
|---|
| Number of Residues
| 873 |
| Molecular Weight
| 98096.8 |
| Theoretical pI
| 5.91 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Zinc fingers and homeoboxes protein 1
MASRRKSTTPCMVLASEQDPDLELISDLDEGPPVLTPVENTRAESISSDEEVHESVDSDN
QQNKKVEGGYECKYCTFQTPDLNMFTFHVDSEHPNVVLNSSYVCVECNFLTKRYDALSEH
NLKYHPGEENFKLTMVKRNNQTIFEQTINDLTFDGSFVKEENAEQAESTEVSSSGISISK
TPIMKMMKNKVENKRIAVHHNSVEDVPEEKENEIKPDREEIVENPSSSASESNTSTSIVN
RIHPSTASTVVTPAAVLPGLAQVITAVSAQQNSNLIPKVLIPVNSIPTYNAALDNNPLLL
NTYNKFPYPTMSEITVLSAQAKYTEEQIKIWFSAQRLKHGVSWTPEEVEEARRKQFNGTV
HTVPQTITVIPTHISTGSNGLPSILQTCQIVGQPGLVLTQVAGTNTLPVTAPIALTVAGV
PSQNNIQKSQVPAAQPTAETKPATAAVPTSQSVKHETALVNPDSFGIRAKKTKEQLAELK
VSYLKNQFPHDSEIIRLMKITGLTKGEIKKWFSDTRYNQRNSKSNQCLHLNNDSSTTIII
DSSDETTESPTVGTAQPKQSWNPFPDFTPQKFKEKTAEQLRVLQASFLNSSVLTDEELNR
LRAQTKLTRREIDAWFTEKKKSKALKEEKMEIDESNAGSSKEEAGETSPADESGAPKSGS
TGKICKKTPEQLHMLKSAFVRTQWPSPEEYDKLAKESGLARTDIVSWFGDTRYAWKNGNL
KWYYYYQSANSSSMNGLSSLRKRGRGRPKGRGRGRPRGRPRGSKRINNWDRGPSLIKFKT
GTAILKDYYLKHKFLNEQDLDELVNKSHMGYEQVREWFAERQRRSELGIELFEENEEEDE
VIDDQEEDEEETDDSDTWEPPRHVKRKLSKSDD
|
| External Links |
|---|
| GenBank ID Protein
| 5757884 |
| UniProtKB/Swiss-Prot ID
| Q9UKY1 |
| UniProtKB/Swiss-Prot Entry Name
| ZHX1_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AF106862 |
| GeneCard ID
| ZHX1 |
| GenAtlas ID
| ZHX1 |
| HGNC ID
| HGNC:12871 |
| References |
|---|
| General References
| Not Available |