Identification |
HMDB Protein ID
| CDBP04902 |
Secondary Accession Numbers
| Not Available |
Name
| Zinc finger and BTB domain-containing protein 17 |
Description
| Not Available |
Synonyms
|
- Miz-1
- Myc-interacting zinc finger protein 1
- Zinc finger protein 151
- Zinc finger protein 60
|
Gene Name
| ZBTB17 |
Protein Type
| Metal Binding |
Biological Properties |
General Function
| Involved in protein binding |
Specific Function
| May function as a housekeeping DNA-binding protein that regulates the expression of specific genes. Has been shown to bind to the promoters of adenovirus major late protein and cyclin D1 and activate transcription. Also has potent growth arrest activity, probably through inhibition of cell cycle progression. Required for early embryonic development during gastrulation |
GO Classification
|
Component |
cell part |
intracellular |
Function |
ion binding |
cation binding |
metal ion binding |
binding |
transition metal ion binding |
zinc ion binding |
protein binding |
nucleic acid binding |
|
Cellular Location
|
- Nucleus
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Chromosome:1 |
Locus
| 1p36.13 |
SNPs
| ZBTB17 |
Gene Sequence
|
>2412 bp
ATGGACTTTCCCCAGCACAGCCAGCATGTCTTGGAACAGCTGAACCAGCAGCGGCAGCTG
GGGCTTCTCTGTGACTGCACCTTTGTGGTGGACGGTGTTCACTTTAAGGCTCATAAAGCA
GTGCTGGCGGCCTGCAGCGAGTACTTCAAGATGCTCTTCGTGGACCAGAAGGACGTGGTG
CACCTGGACATCAGTAACGCGGCAGGCCTGGGGCAGGTGCTGGAGTTTATGTACACGGCC
AAGCTGAGCCTGAGCCCTGAGAACGTGGATGATGTGCTGGCCGTGGCCACTTTCCTCCAA
ATGCAGGACATCATCACGGCCTGCCATGCCCTCAAGTCACTTGCTGAGCCGGCTACCAGC
CCTGGGGGAAATGCGGAGGCCTTGGCCACAGAAGGAGGGGACAAGAGAGCCAAAGAGGAG
AAGGTGGCCACCAGCACGCTGAGCAGGCTGGAGCAGGCAGGACGCAGCACACCCATAGGC
CCCAGCAGGGACCTCAAGGAGGAGCGCGGCGGTCAGGCCCAGAGTGCGGCCAGCGGTGCA
GAGCAGACAGAGAAAGCCGATGCGCCCCGGGAGCCGCCGCCTGTGGAGCTCAAGCCAGAC
CCCACGAGTGGCATGGCTGCTGCAGAAGCTGAGGCCGCTTTGTCCGAGAGCTCGGAGCAA
GAAATGGAGGTGGAGCCCGCCCGGAAAGGGGAAGAGGAGCAAAAGGAGCAAGAGGAGCAA
GAGGAGGAGGGCGCAGGGCCAGCTGAGGTCAAGGAGGAGGGTTCCCAGCTGGAGAACGGA
GAGGCCCCCGAGGAGAACGAGAATGAGGAGTCAGCGGGCACAGACTCGGGGCAGGAGCTC
GGCTCCGAGGCCCGGGGCCTGCGCTCAGGCACCTACGGCGACCGCACGGAGTCCAAGGCC
TACGGCTCCGTCATCCACAAGTGCGAGGACTGTGGGAAGGAGTTCACGCACACGGGGAAC
TTCAAGCGGCACATCCGCATCCACACGGGGGAGAAGCCCTTCTCGTGCCGGGAGTGCAGC
AAGGCCTTTTCCGACCCGGCCGCGTGCAAGGCCCATGAGAAGACGCACAGCCCTCTGAAG
CCCTACGGCTGCGAGGAGTGCGGGAAGAGCTACCGCCTCATCAGCCTGCTGAACCTGCAC
AAGAAGCGGCACTCGGGCGAGGCGCGCTACCGCTGCGAGGACTGCGGCAAGCTCTTCACC
ACCTCGGGCAACCTCAAGCGCCACCAGCTGGTGCACAGCGGCGAGAAGCCCTACCAGTGC
GACTACTGCGGCCGCTCCTTCTCCGACCCCACTTCCAAGATGCGCCACCTGGAGACCCAC
GACACGGACAAGGAGCACAAGTGCCCACACTGCGACAAGAAGTTCAACCAGGTAGGGAAC
CTGAAGGCCCACCTGAAGATCCACATCGCTGACGGGCCCCTCAAGTGCCGAGAGTGTGGG
AAGCAGTTCACCACCTCAGGGAACCTGAAGCGGCACCTTCGGATCCACAGCGGGGAGAAG
CCCTACGTGTGCATCCACTGCCAGCGACAGTTTGCAGACCCCGGCGCTCTGCAGCGGCAC
GTCCGCATTCACACAGGTGAGAAGCCATGCCAGTGTGTGATGTGCGGTAAGGCCTTCACC
CAGGCCAGCTCCCTCATCGCCCACGTGCGCCAGCACACCGGGGAGAAGCCCTACGTCTGC
GAGCGCTGCGGCAAGAGATTCGTCCAGTCCAGCCAGTTGGCCAATCATATTCGCCACCAC
GACAACATCCGCCCACACAAGTGCAGCGTGTGCAGCAAGGCCTTCGTGAACGTGGGGGAC
CTGTCCAAGCACATCATCATTCACACTGGAGAGAAGCCTTACCTGTGTGATAAGTGTGGG
CGTGGCTTCAACCGGGTAGACAACCTGCGCTCCCACGTGAAGACCGTGCACCAGGGCAAG
GCAGGCATCAAGATCCTGGAGCCCGAGGAGGGCAGTGAGGTCAGCGTGGTCACTGTGGAT
GACATGGTCACGCTGGCTACCGAGGCACTGGCAGCGACAGCCGTCACTCAGCTCACAGTG
GTGCCGGTGGGAGCTGCAGTGACAGCCGATGAGACGGAAGTCCTGAAGGCCGAGATCAGC
AAAGCTGTGAAGCAAGTGCAGGAAGAAGACCCCAACACTCACATCCTCTACGCCTGTGAC
TCCTGTGGGGACAAGTTTCTGGATGCCAACAGCCTGGCTCAGCATGTGCGAATCCACACA
GCCCAGGCACTGGTCATGTTCCAGACAGACGCGGACTTCTATCAGCAGTATGGGCCAGGT
GGCACGTGGCCTGCCGGGCAGGTGCTGCAGGCTGGGGAGCTGGTCTTCCGCCCTCGCGAC
GGGGCTGAGGGCCAGCCCGCACTGGCAGAGACCTCCCCTACAGCTCCTGAATGTCCCCCG
CCTGCCGAGTGA
|
Protein Properties |
Number of Residues
| 803 |
Molecular Weight
| 87927.0 |
Theoretical pI
| 6.42 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
|
Protein Sequence
|
>Zinc finger and BTB domain-containing protein 17
MDFPQHSQHVLEQLNQQRQLGLLCDCTFVVDGVHFKAHKAVLAACSEYFKMLFVDQKDVV
HLDISNAAGLGQVLEFMYTAKLSLSPENVDDVLAVATFLQMQDIITACHALKSLAEPATS
PGGNAEALATEGGDKRAKEEKVATSTLSRLEQAGRSTPIGPSRDLKEERGGQAQSAASGA
EQTEKADAPREPPPVELKPDPTSGMAAAEAEAALSESSEQEMEVEPARKGEEEQKEQEEQ
EEEGAGPAEVKEEGSQLENGEAPEENENEESAGTDSGQELGSEARGLRSGTYGDRTESKA
YGSVIHKCEDCGKEFTHTGNFKRHIRIHTGEKPFSCRECSKAFSDPAACKAHEKTHSPLK
PYGCEECGKSYRLISLLNLHKKRHSGEARYRCEDCGKLFTTSGNLKRHQLVHSGEKPYQC
DYCGRSFSDPTSKMRHLETHDTDKEHKCPHCDKKFNQVGNLKAHLKIHIADGPLKCRECG
KQFTTSGNLKRHLRIHSGEKPYVCIHCQRQFADPGALQRHVRIHTGEKPCQCVMCGKAFT
QASSLIAHVRQHTGEKPYVCERCGKRFVQSSQLANHIRHHDNIRPHKCSVCSKAFVNVGD
LSKHIIIHTGEKPYLCDKCGRGFNRVDNLRSHVKTVHQGKAGIKILEPEEGSEVSVVTVD
DMVTLATEALAATAVTQLTVVPVGAAVTADETEVLKAEISKAVKQVQEEDPNTHILYACD
SCGDKFLDANSLAQHVRIHTAQALVMFQTDADFYQQYGPGGTWPAGQVLQAGELVFRPRD
GAEGQPALAETSPTAPECPPPAE
|
External Links |
GenBank ID Protein
| 7378713 |
UniProtKB/Swiss-Prot ID
| Q13105 |
UniProtKB/Swiss-Prot Entry Name
| ZBT17_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| AL034555 |
GeneCard ID
| ZBTB17 |
GenAtlas ID
| ZBTB17 |
HGNC ID
| HGNC:12936 |
References |
General References
| Not Available |