Identification |
HMDB Protein ID
| CDBP04892 |
Secondary Accession Numbers
| Not Available |
Name
| Hyaluronan and proteoglycan link protein 1 |
Description
| Not Available |
Synonyms
|
- Cartilage-link protein
- Cartilage-linking protein 1
- Proteoglycan link protein
|
Gene Name
| HAPLN1 |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in binding |
Specific Function
| Stabilizes the aggregates of proteoglycan monomers with hyaluronic acid in the extracellular cartilage matrix |
GO Classification
|
Function |
binding |
pattern binding |
polysaccharide binding |
glycosaminoglycan binding |
hyaluronic acid binding |
Process |
cell adhesion |
cellular process |
|
Cellular Location
|
- Secreted
- extracellular space
- extracellular matrix
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Chromosome:5 |
Locus
| 5q14.3 |
SNPs
| HAPLN1 |
Gene Sequence
|
>1065 bp
ATGAAGAGTCTACTTCTTCTGGTGCTGATTTCAATCTGCTGGGCTGATCATCTTTCAGAC
AACTATACTCTGGATCATGACAGAGCTATTCACATCCAAGCAGAAAATGGCCCCCATCTA
CTTGTGGAAGCAGAGCAAGCCAAGGTGTTTTCACACAGAGGTGGCAATGTTACACTGCCA
TGTAAATTTTATCGAGACCCTACAGCATTTGGCTCAGGAATCCATAAAATCCGAATTAAG
TGGACCAAGCTAACTTCGGATTACCTCAAGGAAGTGGATGTTTTTGTTTCCATGGGATAC
CACAAAAAAACCTATGGAGGCTACCAGGGTAGAGTGTTTCTGAAGGGAGGCAGTGATAGT
GATGCTTCTCTGGTCATCACAGACCTCACTCTGGAAGATTATGGGAGATATAAGTGTGAG
GTGATTGAAGGATTAGAAGATGATACTGTTGTGGTAGCACTGGACTTACAAGGTGTGGTA
TTCCCTTACTTTCCACGACTGGGGCGCTACAATCTCAATTTTCACGAGGCGCAGCAGGCG
TGTCTGGACCAGGATGCTGTGATCGCCTCCTTCGACCAGCTGTACGACGCCTGGCGGGGC
GGGCTGGACTGGTGCAATGCCGGCTGGCTCAGTGATGGCTCTGTGCAATATCCCATCACA
AAGCCCAGAGAGCCCTGTGGGGGCCAGAACACAGTGCCCGGAGTCAGGAACTACGGATTT
TGGGATAAAGATAAAAGCAGATATGATGTTTTCTGTTTTACATCCAATTTCAATGGCCGT
TTTTACTATCTGATCCACCCCACCAAACTGACCTATGATGAAGCGGTGCAAGCTTGTCTC
AATGATGGTGCTCAGATTGCAAAAGTGGGCCAGATATTTGCTGCCTGGAAAATTCTCGGA
TATGACCGCTGTGATGCGGGCTGGTTGGCGGATGGCAGCGTCCGCTACCCCATCTCTAGG
CCAAGAAGGCGCTGCAGTCCTACTGAGGCTGCAGTGCGCTTCGTGGGTTTCCCAGATAAA
AAGCATAAGCTGTATGGTGTCTACTGCTTCAGAGCATACAACTGA
|
Protein Properties |
Number of Residues
| 354 |
Molecular Weight
| 40165.2 |
Theoretical pI
| 7.45 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
|
Protein Sequence
|
>Hyaluronan and proteoglycan link protein 1
MKSLLLLVLISICWADHLSDNYTLDHDRAIHIQAENGPHLLVEAEQAKVFSHRGGNVTLP
CKFYRDPTAFGSGIHKIRIKWTKLTSDYLKEVDVFVSMGYHKKTYGGYQGRVFLKGGSDS
DASLVITDLTLEDYGRYKCEVIEGLEDDTVVVALDLQGVVFPYFPRLGRYNLNFHEAQQA
CLDQDAVIASFDQLYDAWRGGLDWCNAGWLSDGSVQYPITKPREPCGGQNTVPGVRNYGF
WDKDKSRYDVFCFTSNFNGRFYYLIHPTKLTYDEAVQACLNDGAQIAKVGQIFAAWKILG
YDRCDAGWLADGSVRYPISRPRRRCSPTEAAVRFVGFPDKKHKLYGVYCFRAYN
|
External Links |
GenBank ID Protein
| 189053949 |
UniProtKB/Swiss-Prot ID
| P10915 |
UniProtKB/Swiss-Prot Entry Name
| HPLN1_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| AK313713 |
GeneCard ID
| HAPLN1 |
GenAtlas ID
| HAPLN1 |
HGNC ID
| HGNC:2380 |
References |
General References
| Not Available |