Identification
HMDB Protein ID CDBP04892
Secondary Accession Numbers Not Available
Name Hyaluronan and proteoglycan link protein 1
Description Not Available
Synonyms
  1. Cartilage-link protein
  2. Cartilage-linking protein 1
  3. Proteoglycan link protein
Gene Name HAPLN1
Protein Type Enzyme
Biological Properties
General Function Involved in binding
Specific Function Stabilizes the aggregates of proteoglycan monomers with hyaluronic acid in the extracellular cartilage matrix
GO Classification
Function
binding
pattern binding
polysaccharide binding
glycosaminoglycan binding
hyaluronic acid binding
Process
cell adhesion
cellular process
Cellular Location
  1. Secreted
  2. extracellular space
  3. extracellular matrix
Pathways
Gene Properties
Chromosome Location Chromosome:5
Locus 5q14.3
SNPs HAPLN1
Gene Sequence
>1065 bp
ATGAAGAGTCTACTTCTTCTGGTGCTGATTTCAATCTGCTGGGCTGATCATCTTTCAGAC
AACTATACTCTGGATCATGACAGAGCTATTCACATCCAAGCAGAAAATGGCCCCCATCTA
CTTGTGGAAGCAGAGCAAGCCAAGGTGTTTTCACACAGAGGTGGCAATGTTACACTGCCA
TGTAAATTTTATCGAGACCCTACAGCATTTGGCTCAGGAATCCATAAAATCCGAATTAAG
TGGACCAAGCTAACTTCGGATTACCTCAAGGAAGTGGATGTTTTTGTTTCCATGGGATAC
CACAAAAAAACCTATGGAGGCTACCAGGGTAGAGTGTTTCTGAAGGGAGGCAGTGATAGT
GATGCTTCTCTGGTCATCACAGACCTCACTCTGGAAGATTATGGGAGATATAAGTGTGAG
GTGATTGAAGGATTAGAAGATGATACTGTTGTGGTAGCACTGGACTTACAAGGTGTGGTA
TTCCCTTACTTTCCACGACTGGGGCGCTACAATCTCAATTTTCACGAGGCGCAGCAGGCG
TGTCTGGACCAGGATGCTGTGATCGCCTCCTTCGACCAGCTGTACGACGCCTGGCGGGGC
GGGCTGGACTGGTGCAATGCCGGCTGGCTCAGTGATGGCTCTGTGCAATATCCCATCACA
AAGCCCAGAGAGCCCTGTGGGGGCCAGAACACAGTGCCCGGAGTCAGGAACTACGGATTT
TGGGATAAAGATAAAAGCAGATATGATGTTTTCTGTTTTACATCCAATTTCAATGGCCGT
TTTTACTATCTGATCCACCCCACCAAACTGACCTATGATGAAGCGGTGCAAGCTTGTCTC
AATGATGGTGCTCAGATTGCAAAAGTGGGCCAGATATTTGCTGCCTGGAAAATTCTCGGA
TATGACCGCTGTGATGCGGGCTGGTTGGCGGATGGCAGCGTCCGCTACCCCATCTCTAGG
CCAAGAAGGCGCTGCAGTCCTACTGAGGCTGCAGTGCGCTTCGTGGGTTTCCCAGATAAA
AAGCATAAGCTGTATGGTGTCTACTGCTTCAGAGCATACAACTGA
Protein Properties
Number of Residues 354
Molecular Weight 40165.2
Theoretical pI 7.45
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["None"]
Protein Sequence
>Hyaluronan and proteoglycan link protein 1
MKSLLLLVLISICWADHLSDNYTLDHDRAIHIQAENGPHLLVEAEQAKVFSHRGGNVTLP
CKFYRDPTAFGSGIHKIRIKWTKLTSDYLKEVDVFVSMGYHKKTYGGYQGRVFLKGGSDS
DASLVITDLTLEDYGRYKCEVIEGLEDDTVVVALDLQGVVFPYFPRLGRYNLNFHEAQQA
CLDQDAVIASFDQLYDAWRGGLDWCNAGWLSDGSVQYPITKPREPCGGQNTVPGVRNYGF
WDKDKSRYDVFCFTSNFNGRFYYLIHPTKLTYDEAVQACLNDGAQIAKVGQIFAAWKILG
YDRCDAGWLADGSVRYPISRPRRRCSPTEAAVRFVGFPDKKHKLYGVYCFRAYN
GenBank ID Protein 189053949
UniProtKB/Swiss-Prot ID P10915
UniProtKB/Swiss-Prot Entry Name HPLN1_HUMAN
PDB IDs Not Available
GenBank Gene ID AK313713
GeneCard ID HAPLN1
GenAtlas ID HAPLN1
HGNC ID HGNC:2380
References
General References Not Available