Identification
HMDB Protein ID CDBP04856
Secondary Accession Numbers Not Available
Name Mitochondrial folate transporter/carrier
Description Not Available
Synonyms
  1. Solute carrier family 25 member 32
Gene Name SLC25A32
Protein Type Transporter
Biological Properties
General Function Involved in transporter activity
Specific Function Transports folate across the inner membranes of mitochondria.
GO Classification
Biological Process
folic acid metabolic process
mitochondrial transport
Cellular Component
integral to membrane
mitochondrial inner membrane
Component
membrane
cell part
organelle membrane
organelle inner membrane
mitochondrial inner membrane
Function
transporter activity
binding
Molecular Function
folic acid transporter activity
Process
establishment of localization
transport
transmembrane transport
Cellular Location
  1. Mitochondrion inner membrane
  2. Multi-pass membrane protein
Pathways
Gene Properties
Chromosome Location 8
Locus 8q22.3
SNPs SLC25A32
Gene Sequence
>948 bp
ATGACGGGCCAGGGCCAGTCGGCGTCCGGGTCGTCGGCGTGGAGCACGGTATTCCGCCAC
GTCCGGTATGAGAACCTGATAGCGGGCGTGAGCGGCGGCGTCTTATCCAACCTTGCGCTG
CATCCGCTCGACCTCGTGAAGATCCGCTTCGCCGTGAGTGATGGATTGGAACTGAGACCG
AAATATAATGGAATTTTACATTGCTTGACTACCATTTGGAAACTTGATGGACTACGGGGA
CTTTATCAAGGAGTAACCCCAAATATATGGGGTGCAGGTTTATCCTGGGGACTCTACTTT
TTCTTTTACAATGCCATCAAGTCATATAAAACAGAAGGAAGAGCTGAACATTTAGAGGCA
ACAGAATACCTTGTCTCAGCTGCTGAAGCTGGAGCCATGACCCTCTGCATTACAAACCCA
TTATGGGTAACAAAAACTCGCCTTATGTTACAGTATGATGCTGTTGTTAACTCCCCACAC
CGACAATATAAAGGAATGTTTGATACACTTGTGAAAATATATAAGTATGAAGGTGTGCGT
GGATTATATAAGGGATTTGTTCCTGGGCTGTTTGGAACATCGCATGGTGCCCTTCAGTTT
ATGGCATATGAATTGCTGAAGTTGAAGTACAACCAGCATATCAATAGATTACCAGAAGCC
CAGTTGAGCACAGTAGAATATATATCTGTTGCAGCACTATCCAAAATATTTGCTGTCGCA
GCAACATACCCATATCAAGTCGTAAGAGCTCGTCTTCAGGATCAACACATGTTTTACAGT
GGTGTAATAGATGTAATCACAAAGACATGGAGGAAAGAAGGCGTCGGTGGATTTTACAAG
GGAATTGCTCCTAATTTGATTAGAGTGACTCCAGCCTGCTGTATTACCTTTGTGGTATAT
GAAAACGTCTCACATTTTTTACTTGACCTTAGAGAAAAGAGAAAGTAA
Protein Properties
Number of Residues 315
Molecular Weight 35406.83
Theoretical pI 9.453
Pfam Domain Function
Signals Not Available
Transmembrane Regions Not Available
Protein Sequence
>Mitochondrial folate transporter/carrier
MTGQGQSASGSSAWSTVFRHVRYENLIAGVSGGVLSNLALHPLDLVKIRFAVSDGLELRP
KYNGILHCLTTIWKLDGLRGLYQGVTPNIWGAGLSWGLYFFFYNAIKSYKTEGRAERLEA
TEYLVSAAEAGAMTLCITNPLWVTKTRLMLQYDAVVNSPHRQYKGMFDTLVKIYKYEGVR
GLYKGFVPGLFGTSHGALQFMAYELLKLKYNQHINRLPEAQLSTVEYISVAALSKIFAVA
ATYPYQVVRARLQDQHMFYSGVIDVITKTWRKEGVGGFYKGIAPNLIRVTPACCITFVVY
ENVSHFLLDLREKRK
GenBank ID Protein 11545417
UniProtKB/Swiss-Prot ID Q9H2D1
UniProtKB/Swiss-Prot Entry Name MFTC_HUMAN
PDB IDs Not Available
GenBank Gene ID AF283645
GeneCard ID SLC25A32
GenAtlas ID SLC25A32
HGNC ID HGNC:29683
References
General References Not Available