Identification |
HMDB Protein ID
| CDBP04839 |
Secondary Accession Numbers
| Not Available |
Name
| CDGSH iron-sulfur domain-containing protein 1 |
Description
| Not Available |
Synonyms
|
- MitoNEET
|
Gene Name
| CISD1 |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in 2 iron, 2 sulfur cluster binding |
Specific Function
| Plays a key role in regulating maximal capacity for electron transport and oxidative phosphorylation. May be involved in Fe-S cluster shuttling and/or in redox reactions |
GO Classification
|
Component |
organelle |
membrane-bounded organelle |
intracellular membrane-bounded organelle |
Function |
iron-sulfur cluster binding |
2 iron, 2 sulfur cluster binding |
binding |
metal cluster binding |
|
Cellular Location
|
- Mitochondrion outer membrane
- Single-pass type III membrane protein
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Chromosome:1 |
Locus
| 10q21.1 |
SNPs
| CISD1 |
Gene Sequence
|
>327 bp
ATGAGTCTGACTTCCAGTTCCAGCGTACGAGTTGAATGGATCGCAGCAGTTACCATTGCT
GCTGGGACAGCTGCAATTGGTTATCTAGCTTACAAAAGATTTTATGTTAAAGATCATCGA
AATAAAGCTATGATAAACCTTCACATCCAGAAAGACAACCCCAAGATAGTACATGCTTTT
GACATGGAGGATTTGGGAGATAAAGCTGTGTACTGCCGTTGTTGGAGGTCCAAAAAGTTC
CCATTCTGTGATGGGGCTCACACAAAACATAACGAAGAGACTGGAGACAATGTGGGCCCT
CTGATCATCAAGAAAAAAGAAACTTAA
|
Protein Properties |
Number of Residues
| 108 |
Molecular Weight
| 12199.0 |
Theoretical pI
| 9.5 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
|
Protein Sequence
|
>CDGSH iron-sulfur domain-containing protein 1
MSLTSSSSVRVEWIAAVTIAAGTAAIGYLAYKRFYVKDHRNKAMINLHIQKDNPKIVHAF
DMEDLGDKAVYCRCWRSKKFPFCDGAHTKHNEETGDNVGPLIIKKKET
|
External Links |
GenBank ID Protein
| 7689005 |
UniProtKB/Swiss-Prot ID
| Q9NZ45 |
UniProtKB/Swiss-Prot Entry Name
| CISD1_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| AF220049 |
GeneCard ID
| CISD1 |
GenAtlas ID
| CISD1 |
HGNC ID
| HGNC:30880 |
References |
General References
| Not Available |