Identification
HMDB Protein ID CDBP04839
Secondary Accession Numbers Not Available
Name CDGSH iron-sulfur domain-containing protein 1
Description Not Available
Synonyms
  1. MitoNEET
Gene Name CISD1
Protein Type Enzyme
Biological Properties
General Function Involved in 2 iron, 2 sulfur cluster binding
Specific Function Plays a key role in regulating maximal capacity for electron transport and oxidative phosphorylation. May be involved in Fe-S cluster shuttling and/or in redox reactions
GO Classification
Component
organelle
membrane-bounded organelle
intracellular membrane-bounded organelle
Function
iron-sulfur cluster binding
2 iron, 2 sulfur cluster binding
binding
metal cluster binding
Cellular Location
  1. Mitochondrion outer membrane
  2. Single-pass type III membrane protein
Pathways
Gene Properties
Chromosome Location Chromosome:1
Locus 10q21.1
SNPs CISD1
Gene Sequence
>327 bp
ATGAGTCTGACTTCCAGTTCCAGCGTACGAGTTGAATGGATCGCAGCAGTTACCATTGCT
GCTGGGACAGCTGCAATTGGTTATCTAGCTTACAAAAGATTTTATGTTAAAGATCATCGA
AATAAAGCTATGATAAACCTTCACATCCAGAAAGACAACCCCAAGATAGTACATGCTTTT
GACATGGAGGATTTGGGAGATAAAGCTGTGTACTGCCGTTGTTGGAGGTCCAAAAAGTTC
CCATTCTGTGATGGGGCTCACACAAAACATAACGAAGAGACTGGAGACAATGTGGGCCCT
CTGATCATCAAGAAAAAAGAAACTTAA
Protein Properties
Number of Residues 108
Molecular Weight 12199.0
Theoretical pI 9.5
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["14-31"]
Protein Sequence
>CDGSH iron-sulfur domain-containing protein 1
MSLTSSSSVRVEWIAAVTIAAGTAAIGYLAYKRFYVKDHRNKAMINLHIQKDNPKIVHAF
DMEDLGDKAVYCRCWRSKKFPFCDGAHTKHNEETGDNVGPLIIKKKET
GenBank ID Protein 7689005
UniProtKB/Swiss-Prot ID Q9NZ45
UniProtKB/Swiss-Prot Entry Name CISD1_HUMAN
PDB IDs Not Available
GenBank Gene ID AF220049
GeneCard ID CISD1
GenAtlas ID CISD1
HGNC ID HGNC:30880
References
General References Not Available