Identification |
HMDB Protein ID
| CDBP04837 |
Secondary Accession Numbers
| Not Available |
Name
| Ammonium transporter Rh type C |
Description
| Not Available |
Synonyms
|
- Rh family type C glycoprotein
- Rh glycoprotein kidney
- Rh type C glycoprotein
- Rhesus blood group family type C glycoprotein
- Tumor-related protein DRC2
|
Gene Name
| RHCG |
Protein Type
| Transporter |
Biological Properties |
General Function
| Involved in ammonium transmembrane transporter activity |
Specific Function
| Functions as an electroneutral and bidirectional ammonium transporter. May regulate transepithelial ammonia secretion.
|
GO Classification
|
Biological Process |
cellular ion homeostasis |
transepithelial ammonium transport |
amine transport |
epithelial cell differentiation |
regulation of pH |
Cellular Component |
basolateral plasma membrane |
apical plasma membrane |
cytoplasmic vesicle |
integral to plasma membrane |
Component |
membrane |
cell part |
Function |
transmembrane transporter activity |
substrate-specific transmembrane transporter activity |
ion transmembrane transporter activity |
cation transmembrane transporter activity |
transporter activity |
organic cation transmembrane transporter activity |
ammonium transmembrane transporter activity |
Molecular Function |
ammonia transmembrane transporter activity |
ammonium transmembrane transporter activity |
ankyrin binding |
Process |
establishment of localization |
transport |
transmembrane transport |
|
Cellular Location
|
- Multi-pass membrane protein
- Apical cell membrane
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| 15 |
Locus
| 15q25 |
SNPs
| RHCG |
Gene Sequence
|
>1440 bp
ATGGCCTGGAACACCAACCTCCGCTGGCGGCTGCCGCTCACCTGCCTGCTCCTGCAGGTG
ATTATGGTGATTCTCTTCGGGGTGTTCGTGCGCTACGACTTCGAGGCCGACGCCCACTGG
TGGTCAGAGAGGACGCACAAGAACTTGAGCGACATGGAGAACGAATTCTACTATCGCTAC
CCAAGCTTCCAGGACGTGCACGTGATGGTCTTCGTGGGCTTCGGCTTCCTCATGACTTTC
CTGCAGCGCTACGGCTTCAGCGCCGTGGGCTTCAACTTCCTGTTGGCAGCCTTCGGCATC
CAGTGGGCGCTGCTCATGCAGGGCTGGTTCCACTTCTTACAAGACCGCTACATCGTCGTG
GGCGTGGAGAACCTCATCAACGCTGACTTCTGCGTGGCCTCTGTCTGCGTGGCCTTTGGG
GCAGTTCTGGGTAAAGTCAGCCCCATTCAGCTGCTCATCATGACTTTCTTCCAAGTGACC
CTCTTCGCTGTGAATGAGTTCATTCTCCTTAACCTGCTAAAGGTGAAGGATGCAGGAGGC
TCCATGACCATCCACACATTTGGCGCCTACTTTGGGCTCACAGTGACCCGGATCCTCTAC
CGACGCAACCTAGAGCAGAGCAAGGAGAGACAGAATTCTGTGTACCAGTCGGACCTCTTT
GCCATGATTGGCACCCTCTTCCTGTGGATGTACTGGCCCAGCTTCAACTCAGCCATATCC
TACCATGGGGACAGCCAGCACCGAGCCGCCATCAACACCTACTGCTCCTTGGCAGCCTGC
GTGCTTACCTCGGTGGCAATATCCAGTGCCCTGCACAAGAAGGGCAAGCTGGACATGGTG
CACATCCAGAATGCCACGCTCGCAGGAGGGGTGGCCGTGGGTACCGCTGCTGAGATGATG
CTCATGCCTTACGGTGCCCTCATCATCGGCTTCGTCTGCGGCATCATCTCCACCCTGGGT
TTTGTATACCTGACCCCATTCCTGGAGTCCCGGCTGCACATCCAGGACACATGTGGCATT
AACAATCTGCATGGCATTCCTGGCATCATAGGCGGCATCGTGGGTGCTGTGACAGCGGCC
TCCGCCAGCCTTGAAGTCTATGGAAAAGAAGGGCTTGTCCATTCCTTTGACTTTCAAGGT
TTCAACGGGGACTGGACCGCAAGAACACAGGGAAAGTTCCAGATTTATGGTCTCTTGGTG
ACCCTGGCCATGGCCCTGATGGGTGGCATCATTGTGGGGCTCATTTTGAGATTACCATTC
TGGGGACAACCTTCAGATGAGAACTGCTTTGAGGATGCGGTCTACTGGGAGATGCCTGAA
GGGAACAGCACTGTCTACATCCCTGAGGACCCCACCTTCAAGCCCTCAGGACCCTCAGTA
CCCTCAGTACCCATGGTGTCCCCACTACCCATGGCTTCCTCGGTACCCTTGGTACCCTAG
|
Protein Properties |
Number of Residues
| 479 |
Molecular Weight
| 53178.56 |
Theoretical pI
| 6.39 |
Pfam Domain Function
|
|
Signals
|
Not Available
|
Transmembrane Regions
|
Not Available
|
Protein Sequence
|
>Ammonium transporter Rh type C
MAWNTNLRWRLPLTCLLLQVIMVILFGVFVRYDFEADAHWWSERTHKNLSDMENEFYYRY
PSFQDVHVMVFVGFGFLMTFLQRYGFSAVGFNFLLAAFGIQWALLMQGWFHFLQDRYIVV
GVENLINADFCVASVCVAFGAVLGKVSPIQLLIMTFFQVTLFAVNEFILLNLLKVKDAGG
SMTIHTFGAYFGLTVTRILYRRNLEQSKERQNSVYQSDLFAMIGTLFLWMYWPSFNSAIS
YHGDSQHRAAINTYCSLAACVLTSVAISSALHKKGKLDMVHIQNATLAGGVAVGTAAEMM
LMPYGALIIGFVCGIISTLGFVYLTPFLESRLHIQDTCGINNLHGIPGIIGGIVGAVTAA
SASLEVYGKEGLVHSFDFQGFNGDWTARTQGKFQIYGLLVTLAMALMGGIIVGLILRLPF
WGQPSDENCFEDAVYWEMPEGNSTVYIPEDPTFKPSGPSVPSVPMVSPLPMASSVPLVP
|
External Links |
GenBank ID Protein
| 6625732 |
UniProtKB/Swiss-Prot ID
| Q9UBD6 |
UniProtKB/Swiss-Prot Entry Name
| RHCG_HUMAN |
PDB IDs
|
|
GenBank Gene ID
| AF193809 |
GeneCard ID
| RHCG |
GenAtlas ID
| RHCG |
HGNC ID
| HGNC:18140 |
References |
General References
| Not Available |