Cannabis Compound Database: Showing Protein Adenosine 3'-phospho 5'-phosphosulfate transporter 2 (CDBP04802)

Identification Biological properties Gene properties Protein properties External links References XML Show 3 compounds

Identification

HMDB Protein ID

CDBP04802

Secondary Accession Numbers

Not Available

Name

Adenosine 3'-phospho 5'-phosphosulfate transporter 2

Description

Not Available

Synonyms

3'-phosphoadenosine 5'-phosphosulfate transporter
PAPS transporter 2
Solute carrier family 35 member B3

Gene Name

SLC35B3

Protein Type

Enzyme

Biological Properties

General Function

Involved in transmembrane transport

Specific Function

Mediates the transport of adenosine 3'-phospho 5'- phosphosulfate (PAPS), from cytosol into Golgi. PAPS is a universal sulfuryl donor for sulfation events that take place in the Golgi. Compensates for the insufficient expression of SLC35B2/PAPST1 during the synthesis of sulfated glycoconjugates in the colon

GO Classification

Process
establishment of localization
transport
transmembrane transport

Cellular Location

Golgi apparatus membrane
Multi-pass membrane protein

Pathways

Not Available

Gene Properties

Chromosome Location

Chromosome:6

Locus

6p24.3

SNPs

SLC35B3

Gene Sequence

>1206 bp
ATGGACTTGACACAGCAAGCAAAAGACATACAGAACATAACAGTCCAGGAAACCAACAAA
AATAACTCTGAAAGCATTGAATGCAGCAAAATAACAATGGATCTCAAGTTCAACAATTCC
AGGAAATATATTTCTATCACTGTGCCATCCAAAACCCAAACAATGTCACCACACATCAAG
TCAGTTGACGACGTTGTGGTACTTGGCATGAATCTCAGCAAGTTTAACAAACTTACTCAG
TTTTTCATATGTGTTGCTGGAGTTTTTGTATTTTACCTAATTTATGGGTATTTACAGGAA
TTAATATTTTCAGTGGAGGGTTTTAAGTCCTGTGGCTGGTACCTTACCTTAGTGCAGTTT
GCCTTTTACTCCATATTTGGCCTAATAGAACTTCAGCTTATTCAGGACAAAAGGAGGAGA
ATACCAGGAAAAACCTACATGATAATAGCTTTTCTAACTGTGGGTACTATGGGGTTATCA
AACACTTCCTTGGGCTACCTGAATTACCCTACCCAAGTCATCTTCAAGTGCTGCAAATTG
ATTCCTGTTATGCTAGGAGGAGTTTTTATTCAAGGAAAGCGTTATAATGTTGCAGATGTG
TCTGCTGCCATATGTATGAGCCTTGGCCTGATATGGTTTACCCTCGCTGACAGCACAACT
GCACCAAATTTCAACCTGACGGGTGTGGTGCTTATTTCCCTGGCACTATGTGCAGATGCC
GTCATTGGAAATGTTCAAGAGAAAGCTATGAAACTTCATAATGCTTCTAATTCTGAAATG
GTATTGTATTCGTATTCAATTGGTTTTGTATACATTTTACTGGGATTGACATGCACTAGT
GGATTAGGCCCTGCAGTAACATTTTGTGCAAAGAATCCAGTTCGGACCTATGGTTATGCG
TTCCTTTTTTCCCTCACTGGATATTTTGGAATCTCCTTTGTTCTGGCTTTGATTAAAATT
TTTGGTGCACTTATTGCTGTAACAGTGACAACAGGAAGAAAAGCAATGACCATTGTACTT
TCGTTTATATTCTTTGCTAAACCATTCACGTTTCAGTATGTATGGTCTGGTTTGTTAGTT
GTCCTTGGTATATTTCTTAATGTTTACAGCAAAAATATGGATAAAATAAGACTACCATCA
CTGTATGATTTGATAAACAAATCAGTGGAAGCAAGAAAGTCAAGGACGCTGGCACAGACT
GTATAG

Protein Properties

Number of Residues

401

Molecular Weight

44592.3

Theoretical pI

9.58

Pfam Domain Function

UAA (PF08449 )

Signals

["None"]

Transmembrane Regions

["78-98", "114-134", "147-167", "170-190", "196-216", "223-243", "267-287", "298-317", "324-346", "349-369"]

Protein Sequence

>Adenosine 3'-phospho 5'-phosphosulfate transporter 2
MDLTQQAKDIQNITVQETNKNNSESIECSKITMDLKFNNSRKYISITVPSKTQTMSPHIK
SVDDVVVLGMNLSKFNKLTQFFICVAGVFVFYLIYGYLQELIFSVEGFKSCGWYLTLVQF
AFYSIFGLIELQLIQDKRRRIPGKTYMIIAFLTVGTMGLSNTSLGYLNYPTQVIFKCCKL
IPVMLGGVFIQGKRYNVADVSAAICMSLGLIWFTLADSTTAPNFNLTGVVLISLALCADA
VIGNVQEKAMKLHNASNSEMVLYSYSIGFVYILLGLTCTSGLGPAVTFCAKNPVRTYGYA
FLFSLTGYFGISFVLALIKIFGALIAVTVTTGRKAMTIVLSFIFFAKPFTFQYVWSGLLV
VLGIFLNVYSKNMDKIRLPSLYDLINKSVEARKSRTLAQTV

External Links

GenBank ID Protein

90991129

UniProtKB/Swiss-Prot ID

Q9H1N7

UniProtKB/Swiss-Prot Entry Name

S35B3_HUMAN

PDB IDs

Not Available

GenBank Gene ID

AB231931

GeneCard ID