Identification |
HMDB Protein ID
| CDBP04786 |
Secondary Accession Numbers
| Not Available |
Name
| Solute carrier family 19 (Thiamine transporter), member 2 |
Description
| Not Available |
Synonyms
|
Not Available
|
Gene Name
| SLC19A2 |
Protein Type
| Transporter |
Biological Properties |
General Function
| Involved in folic acid binding |
Specific Function
| Not Available |
GO Classification
|
Component |
cell part |
membrane |
Function |
active transmembrane transporter activity |
binding |
transmembrane transporter activity |
folic acid binding |
carboxylic acid binding |
amino acid binding |
transporter activity |
secondary active transmembrane transporter activity |
reduced folate carrier activity |
Process |
establishment of localization |
transport |
|
Cellular Location
|
Not Available
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Chromosome:1 |
Locus
| 1q23.3 |
SNPs
| SLC19A2 |
Gene Sequence
|
>1380 bp
ATGGATGTGCCCGGCCCGGTGTCTCGGCGGGCGGCGGCGGCGGCGGCCACTGTGCTCCTG
CGGACCGCTCGGGTCCGTCGCGAATGCTGGTTCTTGCCGACCGCGCTGCTCTGCGCCTAC
GGCTTCTTCGCCAGCCTCAGGCCGTCCGAGCCCTTCCTGACCCCGTACCTGCTGGGGCCG
GACAAGAACCTGACCGAGAGGGAGGTCTTCAATGAAATTTATCCAGTATGGACTTACTCT
TACCTGGTGCTACTGTTTCCTGTGTTCCTTGCCACAGACTACCTCCGTTATAAACCTGTT
GTTCTACTGCAGGGGCTCAGCCTTATTGTTACATGGTTTATGCTGCTCTATGCCCAGGGA
CTGCTGGCCATTCAATTTCTAGAATTTTTTTATGGCATCGCCACAGCCACTGAAATTGCC
TATTACTCTTATATCTACAGTGTGGTGGACCTGGGCATGTACCAGAAAGTCACAAGTTAC
TGTCGAAGTGCCACTTTGGTGGGCTTTACAGTGGGCTCTGTCCTAGGGCAAATCCTTGTC
TCAGTGGCAGGCTGGTCGCTGTTCAGCCTGAATGTCATCTCTCTTACCTGTGTTTCAGTG
GCTTTTGCTGTGGCCTGGTTTTTACCTATGCCACAGAAGAGCCTCTTCTTTCACCACATT
CCTTCTACCTGCCAGAGAGTGAATGGCATCAAGGAACCCAAGCCAGACCGTCTCCTTGTA
TTGAAAGTACTATGGAATGATTTCCTGATGTGCTACTCCTCTCGCCCTCTTCTCTGCTGG
TCTGTGTGGTGGGCCCTCTCTACCTGTGGCTATTTTCAAGTTGTGAACTACACACAGGGC
CTGTGGGAGAAAGTGATGCCTTCTCGCTATGCTGCTATCTATAATGGTGGCGTGGAGGCC
GTTTCAACCTTACTGGGTGCTGTTGCTGTGTTTGCAGTTGGTTATATAAAAATATCCTGG
TCAACTTGGGGAGAAATGACATTATCTCTCTTTTCTCTCCTGATTGCTGCTGCAGTGTAT
ATCATGGACACTGTGGGTAACATTTGGGTGTGCTATGCATCCTATGTTGTCTTCAGAATC
ATCTACATGTTACTCATCACGATAGCAACTTTTCAAATTGCTGCAAACCTCAGCATGGAA
CGCTATGCCCTAGTATTTGGTGTAAATACCTTCATTGCCCTGGCACTGCAGACGCTGCTC
ACTCTAATTGTGGTAGATGCCAGTGGCCTTGGATTAGAAATTACCACTCAGTTTTTGATC
TATGCCAGTTATTTTGCACTCATCGCTGTGGTTTTCCTGGCCAGTGGTGCAGTCAGTGTT
ATGAAGAAATGTAGAAAGCTGGAAGATCCACAATCAAGTTCTCAAGTAACCACTTCATAA
|
Protein Properties |
Number of Residues
| 459 |
Molecular Weight
| 51277.0 |
Theoretical pI
| 8.48 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
|
Protein Sequence
|
>Solute carrier family 19 (Thiamine transporter), member 2
MDVPGPVSRRAAAAAATVLLRTARVRRECWFLPTALLCAYGFFASLRPSEPFLTPYLLGP
DKNLTEREVFNEIYPVWTYSYLVLLFPVFLATDYLRYKPVVLLQGLSLIVTWFMLLYAQG
LLAIQFLEFFYGIATATEIAYYSYIYSVVDLGMYQKVTSYCRSATLVGFTVGSVLGQILV
SVAGWSLFSLNVISLTCVSVAFAVAWFLPMPQKSLFFHHIPSTCQRVNGIKEPKPDRLLV
LKVLWNDFLMCYSSRPLLCWSVWWALSTCGYFQVVNYTQGLWEKVMPSRYAAIYNGGVEA
VSTLLGAVAVFAVGYIKISWSTWGEMTLSLFSLLIAAAVYIMDTVGNIWVCYASYVVFRI
IYMLLITIATFQIAANLSMERYALVFGVNTFIALALQTLLTLIVVDASGLGLEITTQFLI
YASYFALIAVVFLASGAVSVMKKCRKLEDPQSSSQVTTS
|
External Links |
GenBank ID Protein
| 56417731 |
UniProtKB/Swiss-Prot ID
| Q5TIE1 |
UniProtKB/Swiss-Prot Entry Name
| Q5TIE1_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| AL021068 |
GeneCard ID
| SLC19A2 |
GenAtlas ID
| SLC19A2 |
HGNC ID
| HGNC:10938 |
References |
General References
| Not Available |