| Identification |
|---|
| HMDB Protein ID
| CDBP04783 |
| Secondary Accession Numbers
| Not Available |
| Name
| Voltage-gated potassium channel subunit beta-2 |
| Description
| Not Available |
| Synonyms
|
- K(+) channel subunit beta-2
- Kv-beta-2
- hKvbeta2
|
| Gene Name
| KCNAB2 |
| Protein Type
| Transporter |
| Biological Properties |
|---|
| General Function
| Involved in oxidoreductase activity |
| Specific Function
| Accessory potassium channel protein which modulates the activity of the pore-forming alpha subunit. Alters functional properties of Kv1.4 |
| GO Classification
|
| Component |
| cell part |
| intracellular part |
| cytoplasm |
| membrane part |
| intrinsic to membrane |
| integral to membrane |
| Function |
| transporter activity |
| ion channel activity |
| cation channel activity |
| potassium channel activity |
| voltage-gated potassium channel activity |
| catalytic activity |
| transmembrane transporter activity |
| substrate-specific transmembrane transporter activity |
| ion transmembrane transporter activity |
| oxidoreductase activity |
| Process |
| metabolic process |
| establishment of localization |
| transport |
| oxidation reduction |
| transmembrane transport |
| monovalent inorganic cation transport |
| potassium ion transport |
| ion transport |
| cation transport |
|
| Cellular Location
|
- Cytoplasm (Potential)
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 1p36.3 |
| SNPs
| KCNAB2 |
| Gene Sequence
|
>1104 bp
ATGTATCCAGAATCAACGACGGGCTCCCCGGCTCGGCTCTCGCTGCGGCAGACGGGCTCC
CCCGGGATGATCTACAGTACTCGGTATGGGAGTCCCAAAAGACAGCTCCAGTTTTACAGG
AACCTGGGCAAGTCTGGCCTGCGGGTCTCCTGCCTGGGACTTGGAACATGGGTGACCTTC
GGAGGCCAGATCACCGATGAGATGGCAGAGCAGCTCATGACCTTGGCCTATGATAATGGC
ATCAACCTCTTCGATACAGCAGAAGTCTACGCAGCCGGCAAGGCTGAAGTGGTACTGGGA
AACATCATTAAGAAGAAAGGATGGAGGCGGTCCAGCCTCGTCATCACCACCAAGATCTTC
TGGGGCGGAAAGGCGGAGACGGAGCGGGGCCTGTCCAGGAAGCACATAATCGAAGGTCTG
AAAGCTTCCCTGGAGCGACTGCAGCTGGAGTACGTGGATGTGGTGTTTGCCAACCGCCCG
GACCCCAACACCCCGATGGAAGAGACCGTCCGCGCCATGACCCACGTCATCAACCAGGGG
ATGGCCATGTACTGGGGCACGTCACGCTGGAGCTCCATGGAGATCATGGAGGCCTACTCC
GTGGCCCGGCAGTTCAACCTGACCCCGCCCATCTGCGAGCAGGCTGAGTACCACATGTTC
CAGCGTGAGAAAGTGGAGGTGCAGCTGCCGGAGCTGTTCCACAAGATAGGAGTGGGCGCC
ATGACCTGGTCCCCTCTGGCCTGTGGCATTGTTTCTGGCAAGTACGACAGTGGCATCCCA
CCCTACTCAAGAGCCTCCTTGAAGGGCTACCAGTGGCTGAAGGACAAGATCCTCAGTGAG
GAGGGCCGGCGCCAGCAAGCCAAGCTGAAGGAGCTGCAGGCCATCGCCGAGCGCCTGGGC
TGCACCCTGCCCCAGCTGGCCATAGCCTGGTGCCTGAGGAATGAGGGAGTCAGCTCCGTG
CTCCTGGGGGCCTCCAATGCGGACCAGCTCATGGAGAACATTGGGGCAATACAGGTCCTT
CCGAAACTGTCGTCTTCCATTATCCACGAGATTGATAGTATTTTGGGCAATAAACCCTAC
AGCAAAAAGGACTACAGATCCTAA
|
| Protein Properties |
|---|
| Number of Residues
| 367 |
| Molecular Weight
| 40999.9 |
| Theoretical pI
| 9.32 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Voltage-gated potassium channel subunit beta-2
MYPESTTGSPARLSLRQTGSPGMIYSTRYGSPKRQLQFYRNLGKSGLRVSCLGLGTWVTF
GGQITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVLGNIIKKKGWRRSSLVITTKIF
WGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFANRPDPNTPMEETVRAMTHVINQG
MAMYWGTSRWSSMEIMEAYSVARQFNLTPPICEQAEYHMFQREKVEVQLPELFHKIGVGA
MTWSPLACGIVSGKYDSGIPPYSRASLKGYQWLKDKILSEEGRRQQAKLKELQAIAERLG
CTLPQLAIAWCLRNEGVSSVLLGASNADQLMENIGAIQVLPKLSSSIIHEIDSILGNKPY
SKKDYRS
|
| External Links |
|---|
| GenBank ID Protein
| 2599568 |
| UniProtKB/Swiss-Prot ID
| Q13303 |
| UniProtKB/Swiss-Prot Entry Name
| KCAB2_HUMAN |
| PDB IDs
|
|
| GenBank Gene ID
| AF029749 |
| GeneCard ID
| KCNAB2 |
| GenAtlas ID
| KCNAB2 |
| HGNC ID
| HGNC:6229 |
| References |
|---|
| General References
| Not Available |