| Identification |
|---|
| HMDB Protein ID
| CDBP04771 |
| Secondary Accession Numbers
| Not Available |
| Name
| Kinesin-like protein KIFC1 |
| Description
| Not Available |
| Synonyms
|
- Kinesin-like protein 2
- Kinesin-related protein HSET
|
| Gene Name
| KIFC1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in microtubule motor activity |
| Specific Function
| Minus end-directed microtubule-dependent motor required for bipolar spindle formation. May contribute to movement of early endocytic vesicles |
| GO Classification
|
| Function |
| hydrolase activity, acting on acid anhydrides |
| hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides |
| pyrophosphatase activity |
| binding |
| catalytic activity |
| hydrolase activity |
| motor activity |
| nucleoside binding |
| purine nucleoside binding |
| adenyl nucleotide binding |
| adenyl ribonucleotide binding |
| atp binding |
| microtubule motor activity |
| nucleoside-triphosphatase activity |
| Process |
| cellular process |
| microtubule-based process |
| microtubule-based movement |
|
| Cellular Location
|
- Nucleus
- Cytoplasm
- Cytoplasm
- cytoskeleton
- cytoskeleton
- spindle
- centrosome
- Early endosome
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:6 |
| Locus
| 6p21.3 |
| SNPs
| KIFC1 |
| Gene Sequence
|
>2022 bp
ATGGATCCGCAGAGGTCCCCCCTATTGGAAGTAAAGGGGAACATAGAACTGAAGAGACCT
CTGATTAAGGCCCCTTCCCAGCTGCCTCTCTCAGGAAGCAGACTCAAGAGGAGGCCTGAC
CAGATGGAAGATGGCCTGGAGCCTGAGAAGAAACGGACAAGAGGCCTGGGTGCAACGACC
AAAATTACCACATCCCACCCAAGAGTTCCATCCCTCACTACAGTGCCACAGACACAAGGC
CAGACCACAGCTCAAAAAGTTTCCAAGAAGACAGGACCCCGGTGTTCCACAGCTATTGCC
ACAGGGTTGAAGAACCAGAAGCCAGTTCCTGCTGTTCCTGTCCAGAAGTCTGGCACATCA
GGTGTTCCTCCCATGGCAGGAGGGAAGAAACCCAGCAAACGTCCAGCCTGGGACTTAAAG
GGTCAGTTATGTGACCTAAATGCAGAACTAAAACGGTGCCGTGAGAGGACTCAAACGTTG
GACCAAGAGAACCAGCAGCTTCAGGACCAGCTCAGAGATGCCCAGCAGCAGGTCAAGGCC
CTGGGGACAGAGCGCACAACACTGGAGGGGCATTTAGCCAAGGTACAGGCCCAGGCTGAG
CAGGGCCAACAGGAGCTGAAGAACTTGCGTGCTTGTGTCCTGGAGCTGGAAGAGCGGCTG
AGCACGCAGGAGGGCTTGGTGCAAGAGCTTCAGAAAAAACAGGTGGAATTGCAGGAAGAA
CGGAGGGGACTGATGTCCCAACTAGAGGAGAAGGAGAGGAGGCTGCAGACATCAGAAGCA
GCCCTGTCAAGCAGCCAAGCAGAGGTGGCATCTCTGCGGCAGGAGACTGTGGCCCAGGCA
GCCTTACTGACTGAGCGGGAAGAACGTCTTCATGGGCTAGAAATGGAGCGCCGGCGACTG
CACAACCAGCTGCAGGAACTCAAGGGCAACATCCGTGTATTCTGCCGGGTCCGCCCTGTC
CTGCCGGGGGAGCCCACTCCACCCCCTGGCCTCCTCCTGTTTCCCTCTGGCCCTGGTGGG
CCCTCTGATCCTCCAACCCGCCTTAGCCTCTCCCGGTCTGACGAGCGGCGTGGGACCCTG
AGTGGGGCACCAGCTCCCCCAACTCGCCATGATTTTTCCTTTGACCGGGTATTCCCACCA
GGAAGTGGACAGGATGAAGTGTTTGAAGAGATTGCCATGCTTGTCCAGTCAGCCCTGGAT
GGCTATCCAGTATGCATCTTTGCCTATGGCCAGACAGGCAGTGGCAAGACCTTCACAATG
GAGGGTGGGCCTGGGGGAGACCCCCAGTTGGAGGGGCTGATCCCTCGGGCCCTGCGGCAC
CTCTTCTCTGTGGCTCAGGAGCTGAGTGGTCAGGGCTGGACCTACAGCTTTGTAGCAAGC
TACGTAGAGATCTACAATGAGACTGTCCGGGACCTGCTGGCCACTGGAACCCGGAAGGGT
CAAGGGGGCGAGTGTGAGATTCGCCGTGCAGGGCCAGGGAGTGAGGAGCTCACTGTCACC
AATGCTCGATATGTCCCTGTCTCCTGTGAGAAAGAAGTGGACGCCCTGCTTCATCTGGCC
CGCCAGAATCGGGCTGTGGCCCGCACAGCCCAGAATGAACGGTCATCACGCAGCCACAGT
GTATTCCAGCTACAGATTTCTGGGGAGCACTCCAGCCGAGGCCTGCAGTGTGGGGCCCCC
CTCAGTCTTGTGGACCTGGCCGGGAGTGAGCGACTTGACCCCGGCTTAGCCCTCGGCCCC
GGGGAGCGGGAACGCCTTCGGGAAACACAGGCCATTAACAGCAGCCTGTCCACGCTGGGG
CTGGTTATCATGGCCCTGAGCAACAAGGAGTCCCACGTGCCTTACCGGAACAGCAAACTG
ACCTACCTGCTGCAGAACTCTCTGGGTGGTAGTGCTAAGATGCTCATGTTTGTGAACATT
TCTCCACTGGAAGAGAACGTCTCCGAGTCCCTCAACTCTCTACGCTTTGCCTCCAAGGTG
AACCAGTGTGTTATTGGTACTGCTCAGGCCAACAGGAAGTGA
|
| Protein Properties |
|---|
| Number of Residues
| 673 |
| Molecular Weight
| 73747.1 |
| Theoretical pI
| 9.35 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Kinesin-like protein KIFC1
MDPQRSPLLEVKGNIELKRPLIKAPSQLPLSGSRLKRRPDQMEDGLEPEKKRTRGLGATT
KITTSHPRVPSLTTVPQTQGQTTAQKVSKKTGPRCSTAIATGLKNQKPVPAVPVQKSGTS
GVPPMAGGKKPSKRPAWDLKGQLCDLNAELKRCRERTQTLDQENQQLQDQLRDAQQQVKA
LGTERTTLEGHLAKVQAQAEQGQQELKNLRACVLELEERLSTQEGLVQELQKKQVELQEE
RRGLMSQLEEKERRLQTSEAALSSSQAEVASLRQETVAQAALLTEREERLHGLEMERRRL
HNQLQELKGNIRVFCRVRPVLPGEPTPPPGLLLFPSGPGGPSDPPTRLSLSRSDERRGTL
SGAPAPPTRHDFSFDRVFPPGSGQDEVFEEIAMLVQSALDGYPVCIFAYGQTGSGKTFTM
EGGPGGDPQLEGLIPRALRHLFSVAQELSGQGWTYSFVASYVEIYNETVRDLLATGTRKG
QGGECEIRRAGPGSEELTVTNARYVPVSCEKEVDALLHLARQNRAVARTAQNERSSRSHS
VFQLQISGEHSSRGLQCGAPLSLVDLAGSERLDPGLALGPGERERLRETQAINSSLSTLG
LVIMALSNKESHVPYRNSKLTYLLQNSLGGSAKMLMFVNISPLEENVSESLNSLRFASKV
NQCVIGTAQANRK
|
| External Links |
|---|
| GenBank ID Protein
| 167555110 |
| UniProtKB/Swiss-Prot ID
| Q9BW19 |
| UniProtKB/Swiss-Prot Entry Name
| KIFC1_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_002263.3 |
| GeneCard ID
| KIFC1 |
| GenAtlas ID
| KIFC1 |
| HGNC ID
| HGNC:6389 |
| References |
|---|
| General References
| Not Available |