Identification |
HMDB Protein ID
| CDBP04768 |
Secondary Accession Numbers
| Not Available |
Name
| ATP-binding cassette sub-family F member 1 |
Description
| Not Available |
Synonyms
|
- ATP-binding cassette 50
- TNF-alpha-stimulated ABC protein
|
Gene Name
| ABCF1 |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in ATP binding |
Specific Function
| May function in mRNA translation |
GO Classification
|
Function |
binding |
nucleotide binding |
catalytic activity |
hydrolase activity |
nucleoside binding |
purine nucleoside binding |
adenyl nucleotide binding |
adenyl ribonucleotide binding |
atp binding |
atpase activity |
nucleoside-triphosphatase activity |
hydrolase activity, acting on acid anhydrides |
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides |
pyrophosphatase activity |
|
Cellular Location
|
- Cytoplasmic
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Chromosome:6 |
Locus
| 6p21.33 |
SNPs
| ABCF1 |
Gene Sequence
|
>2538 bp
ATGCCGAAGGCGCCCAAGCAGCAGCCGCCGGAGCCCGAGTGGATCGGGGACGGAGAGAGC
ACGAGCCCATCAGACAAAGTGGTGAAGAAAGGGAAGAAGGACAAGAAGATCAAAAAAACG
TTCTTTGAAGAGCTGGCAGTAGAAGATAAACAGGCTGGGGAAGAAGAGAAAGTGCTCAAG
GAGAAGGAGCAGCAGCAGCAGCAACAGCAACAGCAGCAAAAAAAAAAGCGAGATACCCGA
AAAGGCAGGCGGAAGAAGGATGTGGATGATGATGGAGAAGAGAAAGAGCTCATGGAGCGT
CTTAAGAAGCTCTCAGTGCCAACCAGTGATGAGGAGGATGAAGTACCCGCCCCAAAACCC
CGCGGAGGGAAGAAAACCAAGGGTGGTAATGTTTTTGCAGCCCTGATTCAGGATCAGAGT
GAGGAAGAGGAGGAGGAAGAAAAACATCCTCCTAAGCCTGCCAAGCCGGAGAAGAATCGG
ATCAATAAGGCCGTATCTGAGGAACAGCAGCCTGCACTCAAGGGCAAAAAGGGAAAGGAA
GAGAAGTCAAAAGGGAAGGCTAAGCCTCAAAATAAATTCGCTGCTCTGGACAATGAAGAG
GAGGATAAAGAAGAAGAAATTATAAAGGAAAAGGAGCCTCCCAAACAAGGGAAGGAGAAG
GCCAAGAAGGCAGAGCAGGGTTCAGAGGAAGAAGGAGAAGGGGAAGAAGAGGAGGAGGAA
GGAGGAGAGTCTAAGGCAGATGATCCCTATGCTCATCTTAGCAAAAAGGAGAAGAAAAAG
CTGAAAAAACAGATGGAGTATGAGCGCCAAGTGGCTTCATTAAAAGCAGCCAATGCAGCT
GAAAATGACTTCTCCGTGTCCCAGGCGGAGATGTCCTCCCGCCAAGCCATGTTAGAAAAT
GCATCTGACATCAAGCTGGAGAAGTTCAGCATCTCCGCTCATGGCAAGGAGCTGTTCGTC
AATGCAGACCTGTACATTGTAGCCGGCCGCCGCTACGGGCTGGTAGGACCCAATGGCAAG
GGCAAGACCACACTCCTCAAGCACATTGCCAACCGAGCCCTGAGCATCCCTCCCAACATT
GATGTGTTGCTGTGTGAGCAGGAGGTGGTAGCAGATGAGACACCAGCAGTCCAGGCTGTT
CTTCGAGCTGACACCAAGCGATTGAAGCTGCTGGAAGAGGAGCGGCGGCTTCAGGGACAG
CTGGAACAAGGGGATGACACAGCTGCTGAGAGGCTAGAGAAGGTGTATGAGGAATTGCGG
GCCACTGGGGCGGCAGCTGCAGAGGCCAAAGCACGGCGGATCCTGGCTGGCCTGGGCTTT
GACCCTGAAATGCAGAATCGACCCACACAGAAGTTCTCAGGGGGCTGGCGCATGCGTGTC
TCCCTGGCCAGGGCACTGTTCATGGAGCCCACACTGCTGATGCTGGATGAGCCCACCAAC
CACCTGGACCTCAACGCTGTCATCTGGCTTAATAACTACCTCCAGGGCTGGCGGAAGACC
TTGCTGATCGTCTCCCATGACCAGGGCTTCTTGGATGATGTCTGCACTGATATCATCCAC
CTCGATGCCCAGCGGCTCCACTACTATAGGGGCAATTACATGACCTTCAAAAAGATGTAC
CAGCAGAAGCAGAAAGAACTGCTGAAACAGTATGAGAAGCAAGAGAAAAAGCTGAAGGAG
CTGAAGGCAGGCGGGAAGTCCACCAAGCAGGCGGAAAAACAAACGAAGGAAGCCCTGACT
CGGAAGCAGCAGAAATGCCGACGGAAAAACCAAGATGAGGAATCCCAGGAGGCCCCTGAG
CTCCTGAAGCGCCCTAAGGAGTACACTGTGCGCTTCACTTTTCCAGACCCCCCACCACTC
AGCCCTCCAGTGCTGGGTCTGCATGGTGTGACATTCGGCTACCAGGGACAGAAACCACTC
TTTAAGAACTTGGATTTTGGCATCGACATGGATTCAAGGATTTGCATTGTGGGCCCTAAT
GGTGTGGGGAAGAGTACGCTACTCCTGCTGCTGACTGGCAAGCTGACACCGACCCATGGG
GAAATGAGAAAGAACCACCGGCTGAAAATTGGCTTCTTCAACCAGCAGTATGCAGAGCAG
CTGCGCATGGAGGAGACGCCCACTGAGTACCTGCAGCGGGGCTTCAACCTGCCCTACCAG
GATGCCCGCAAGTGCCTGGGCCGCTTCGGCCTGGAGAGTCACGCCCACACCATCCAGATC
TGCAAACTCTCTGGTGGTCAGAAGGCGCGAGTTGTGTTTGCTGAGCTGGCCTGTCGGGAA
CCTGATGTCCTCATCTTGGACGAGCCAACCAATAACCTGGACATAGAGTCTATTGATGCT
CTAGGGGAGGCCATCAATGAATACAAGGGTGCTGTGATCGTTGTCAGCCATGATGCCCGA
CTCATCACAGAAACCAATTGCCAGCTGTGGGTGGTGGAGGAGCAGAGTGTTAGCCAAATC
GATGGTGACTTTGAAGACTACAAGCGGGAGGTGTTGGAGGCCCTGGGTGAAGTCATGGTC
AGCCGGCCCCGAGAGTGA
|
Protein Properties |
Number of Residues
| 845 |
Molecular Weight
| 95925.2 |
Theoretical pI
| 6.77 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
|
Protein Sequence
|
>ATP-binding cassette sub-family F member 1
MPKAPKQQPPEPEWIGDGESTSPSDKVVKKGKKDKKIKKTFFEELAVEDKQAGEEEKVLK
EKEQQQQQQQQQQKKKRDTRKGRRKKDVDDDGEEKELMERLKKLSVPTSDEEDEVPAPKP
RGGKKTKGGNVFAALIQDQSEEEEEEEKHPPKPAKPEKNRINKAVSEEQQPALKGKKGKE
EKSKGKAKPQNKFAALDNEEEDKEEEIIKEKEPPKQGKEKAKKAEQGSEEEGEGEEEEEE
GGESKADDPYAHLSKKEKKKLKKQMEYERQVASLKAANAAENDFSVSQAEMSSRQAMLEN
ASDIKLEKFSISAHGKELFVNADLYIVAGRRYGLVGPNGKGKTTLLKHIANRALSIPPNI
DVLLCEQEVVADETPAVQAVLRADTKRLKLLEEERRLQGQLEQGDDTAAERLEKVYEELR
ATGAAAAEAKARRILAGLGFDPEMQNRPTQKFSGGWRMRVSLARALFMEPTLLMLDEPTN
HLDLNAVIWLNNYLQGWRKTLLIVSHDQGFLDDVCTDIIHLDAQRLHYYRGNYMTFKKMY
QQKQKELLKQYEKQEKKLKELKAGGKSTKQAEKQTKEALTRKQQKCRRKNQDEESQEAPE
LLKRPKEYTVRFTFPDPPPLSPPVLGLHGVTFGYQGQKPLFKNLDFGIDMDSRICIVGPN
GVGKSTLLLLLTGKLTPTHGEMRKNHRLKIGFFNQQYAEQLRMEETPTEYLQRGFNLPYQ
DARKCLGRFGLESHAHTIQICKLSGGQKARVVFAELACREPDVLILDEPTNNLDIESIDA
LGEAINEYKGAVIVVSHDARLITETNCQLWVVEEQSVSQIDGDFEDYKREVLEALGEVMV
SRPRE
|
External Links |
GenBank ID Protein
| 69354671 |
UniProtKB/Swiss-Prot ID
| Q8NE71 |
UniProtKB/Swiss-Prot Entry Name
| ABCF1_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| NM_001025091.1 |
GeneCard ID
| ABCF1 |
GenAtlas ID
| ABCF1 |
HGNC ID
| HGNC:70 |
References |
General References
| Not Available |