| Identification |
|---|
| HMDB Protein ID
| CDBP04753 |
| Secondary Accession Numbers
| Not Available |
| Name
| CD97 antigen |
| Description
| Not Available |
| Synonyms
|
- CD97 antigen
- CD97 antigen subunit alpha
- CD97 antigen subunit beta
- Leukocyte antigen CD97
|
| Gene Name
| CD97 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in calcium ion binding |
| Specific Function
| Receptor potentially involved in both adhesion and signaling processes early after leukocyte activation. Plays an essential role in leukocyte migration |
| GO Classification
|
| Component |
| membrane |
| cell part |
| Function |
| calcium ion binding |
| ion binding |
| cation binding |
| metal ion binding |
| binding |
| receptor activity |
| transmembrane receptor activity |
| molecular transducer activity |
| signal transducer activity |
| g-protein coupled receptor activity |
| Process |
| neuropeptide signaling pathway |
| signaling |
| signaling pathway |
| cell surface receptor linked signaling pathway |
| g-protein coupled receptor protein signaling pathway |
|
| Cellular Location
|
- extracellular space
- CD97 antigen subunit alpha:Secreted
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 19p13 |
| SNPs
| CD97 |
| Gene Sequence
|
>2508 bp
ATGGGAGGCCGCGTCTTTCTCGCATTCTGTGTCTGGCTGACTCTGCCGGGAGCTGAAACC
CAGGACTCCAGGGGCTGTGCCCGGTGGTGCCCTCAGAACTCCTCGTGTGTCAATGCCACC
GCCTGTCGCTGCAATCCAGGGTTCAGCTCTTTTTCTGAGATCATCACCACCCCGACGGAG
ACTTGTGACGACATCAACGAGTGTGCAACACCGTCGAAAGTGTCATGCGGAAAATTCTCG
GACTGCTGGAACACAGAGGGGAGCTACGACTGCGTGTGCAGCCCGGGATATGAGCCTGTT
TCTGGGGCAAAAACATTCAAGAATGAGAGCGAGAACACCTGTCAAGATGTGGACGAATGT
CAGCAGAACCCAAGGCTCTGTAAAAGCTACGGCACCTGCGTCAACACCCTTGGCAGCTAT
ACCTGCCAGTGCCTGCCTGGCTTCAAGTTCATACCTGAGGATCCGAAGGTCTGCACAGAT
GTGAATGAATGCACCTCCGGACAAAACCCGTGCCACAGCTCCACCCACTGCCTCAACAAC
GTGGGCAGCTATCAGTGCCGCTGCCGCCCGGGCTGGCAACCGATTCCGGGGTCCCCCAAT
GGCCCAAACAATACCGTCTGTGAAGATGTGGACGAGTGCAGCTCCGGGCAGCATCAGTGT
GACAGCTCCACCGTCTGCTTCAACACCGTGGGTTCATACAGCTGCCGCTGCCGCCCAGGC
TGGAAGCCCAGACACGGAATCCCGAATAACCAAAAGGACACTGTCTGTGAAGATATGACT
TTCTCCACCTGGACCCCGCCCCCTGGAGTCCACAGCCAGACGCTTTCCCGATTCTTCGAC
AAAGTCCAGGACCTGGGCAGAGACTCCAAGACAAGCTCAGCCGAGGTCACCATCCAGAAT
GTCATCAAATTGGTGGATGAACTGATGGAAGCTCCTGGAGACGTAGAGGCCCTGGCGCCA
CCTGTCCGGCACCTCATAGCCACCCAGCTGCTCTCAAACCTTGAAGATATCATGAGGATC
CTGGCCAAGAGCCTGCCTAAAGGCCCCTTCACCTACATTTCCCCTTCGAACACAGAGCTG
ACCCTGATGATCCAGGAGCGGGGGGACAAGAACGTCACTATGGGTCAGAGCAGCGCACGC
ATGAAGCTGAATTGGGCTGTGGCAGCTGGAGCCGAGGATCCAGGCCCCGCCGTGGCGGGC
ATCCTCTCCATCCAGAACATGACGACATTGCTGGCCAATGCCTCCTTGAACCTGCATTCC
AAGAAGCAAGCCGAACTGGAGGAGATATATGAAAGCAGCATCCGTGGTGTCCAACTCAGA
CGCCTCTCTGCCGTCAACTCCATCTTTCTGAGCCACAACAACACCAAGGAACTCAACTCC
CCCATCCTTTTCGCCTTCTCCCACCTTGAGTCCTCCGATGGGGAGGCGGGAAGAGACCCT
CCTGCCAAGGACGTGATGCCTGGGCCACGGCAGGAGCTGCTCTGTGCCTTCTGGAAGAGT
GACAGCGACAGGGGAGGGCACTGGGCCACCGAGGGCTGCCAGGTGCTGGGCAGCAAGAAC
GGCAGCACCACCTGCCAATGCAGCCACCTGAGCAGCTTTGCGATCCTTATGGCTCATTAT
GACGTGGAGGACTGGAAGCTGACCCTGATCACCAGGGTGGGACTGGCGCTGTCACTCTTC
TGCCTGCTGCTGTGCATCCTCACTTTCCTGCTGGTGCGGCCCATCCAGGGCTCGCGCACC
ACCATACACCTGCACCTCTGCATCTGCCTCTTCGTGGGCTCCACCATCTTCCTGGCCGGC
ATCGAGAACGAAGGCGGCCAGGTGGGGCTGCGCTGCCGCCTGGTGGCCGGGCTGCTGCAC
TACTGTTTCCTGGCCGCCTTCTGCTGGATGAGCCTCGAAGGCCTGGAGCTCTACTTTCTT
GTGGTGCGCGTGTTCCAAGGCCAGGGCCTGAGTACGCGCTGGCTCTGCCTGATCGGCTAT
GGCGTGCCCCTGCTCATCGTGGGCGTCTCGGCTGCCATCTACAGCAAGGGCTACGGCCGC
CCCAGATACTGCTGGTTGGACTTTGAGCAGGGCTTCCTCTGGAGCTTCTTGGGACCTGTG
ACCTTCATCATTTTGTGCAATGCTGTCATTTTCGTGACTACCGTCTGGAAGCTCACTCAG
AAGTTTTCTGAAATCAATCCAGACATGAAGAAATTAAAGAAGGCGAGGGCGCTGACCATC
ACGGCCATCGCGCAGCTCTTCCTGTTGGGCTGCACCTGGGTCTTTGGCCTGTTCATCTTC
GACGATCGGAGCTTGGTGCTGACCTATGTGTTTACCATCCTCAACTGCCTGCAGGGCGCC
TTCCTCTACCTGCTGCACTGCCTGCTCAACAAGAAGGTTCGGGAAGAATACCGGAAGTGG
GCCTGCCTAGTTGCTGGGGGGAGCAAGTACTCAGAATTCACCTCCACCACGTCTGGCACT
GGCCACAATCAGACCCGGGCCCTCAGGGCATCAGAGTCCGGCATATGA
|
| Protein Properties |
|---|
| Number of Residues
| 835 |
| Molecular Weight
| 91868.4 |
| Theoretical pI
| 6.87 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
- ["553-572", "582-601", "621-642", "654-674", "692-712", "740-760", "767-789"]
|
| Protein Sequence
|
>CD97 antigen
MGGRVFLAFCVWLTLPGAETQDSRGCARWCPQNSSCVNATACRCNPGFSSFSEIITTPTE
TCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDEC
QQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNN
VGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPG
WKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLGRDSKTSSAEVTIQN
VIKLVDELMEAPGDVEALAPPVRHLIATQLLSNLEDIMRILAKSLPKGPFTYISPSNTEL
TLMIQERGDKNVTMGQSSARMKLNWAVAAGAEDPGPAVAGILSIQNMTTLLANASLNLHS
KKQAELEEIYESSIRGVQLRRLSAVNSIFLSHNNTKELNSPILFAFSHLESSDGEAGRDP
PAKDVMPGPRQELLCAFWKSDSDRGGHWATEGCQVLGSKNGSTTCQCSHLSSFAILMAHY
DVEDWKLTLITRVGLALSLFCLLLCILTFLLVRPIQGSRTTIHLHLCICLFVGSTIFLAG
IENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQGQGLSTRWLCLIGY
GVPLLIVGVSAAIYSKGYGRPRYCWLDFEQGFLWSFLGPVTFIILCNAVIFVTTVWKLTQ
KFSEINPDMKKLKKARALTITAIAQLFLLGCTWVFGLFIFDDRSLVLTYVFTILNCLQGA
FLYLLHCLLNKKVREEYRKWACLVAGGSKYSEFTSTTSGTGHNQTRALRASESGI
|
| External Links |
|---|
| GenBank ID Protein
| 17978491 |
| UniProtKB/Swiss-Prot ID
| P48960 |
| UniProtKB/Swiss-Prot Entry Name
| CD97_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_078481.2 |
| GeneCard ID
| CD97 |
| GenAtlas ID
| CD97 |
| HGNC ID
| HGNC:1711 |
| References |
|---|
| General References
| Not Available |