| Identification |
|---|
| HMDB Protein ID
| CDBP04748 |
| Secondary Accession Numbers
| Not Available |
| Name
| N-arachidonyl glycine receptor |
| Description
| Not Available |
| Synonyms
|
- G-protein coupled receptor 18
- NAGly receptor
|
| Gene Name
| GPR18 |
| Protein Type
| Receptor |
| Biological Properties |
|---|
| General Function
| Involved in G-protein coupled receptor protein signaling pathway |
| Specific Function
| Receptor for N-arachidonyl glycine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. May contribute to regulation of the immune system |
| GO Classification
|
| Component |
| intrinsic to membrane |
| integral to membrane |
| cell part |
| membrane part |
| Function |
| nucleotide receptor activity, g-protein coupled |
| purinergic nucleotide receptor activity, g-protein coupled |
| receptor activity |
| transmembrane receptor activity |
| molecular transducer activity |
| signal transducer activity |
| g-protein coupled receptor activity |
| Process |
| signaling |
| signaling pathway |
| cell surface receptor linked signaling pathway |
| g-protein coupled receptor protein signaling pathway |
|
| Cellular Location
|
- Cell membrane
- Multi-pass membrane protein
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 13q32 |
| SNPs
| GPR18 |
| Gene Sequence
|
>996 bp
ATGATCACCCTGAACAATCAAGATCAACCTGTCCCTTTTAACAGCTCACATCCAGATGAA
TACAAAATTGCAGCCCTTGTCTTCTATAGCTGTATCTTCATAATTGGATTATTTGTTAAC
ATCACTGCATTATGGGTTTTCAGTTGTACCACCAAGAAGAGAACCACGGTAACCATCTAT
ATGATGAATGTGGCATTAGTGGACTTGATATTTATAATGACTTTACCCTTTCGAATGTTT
TATTATGCAAAAGATGAATGGCCATTTGGAGAGTACTTCTGCCAGATTCTTGGAGCTCTC
ACAGTGTTTTACCCAAGCATTGCTTTATGGCTTCTTGCCTTTATTAGTGCTGACAGATAC
ATGGCCATTGTACAGCCGAAGTACGCCAAAGAACTTAAAAACACGTGCAAAGCCGTGCTG
GCGTGTGTGGGAGTCTGGATAATGACCCTGACCACGACCACCCCTCTGCTACTGCTCTAT
AAAGACCCAGATAAAGACTCCACTCCCGCCACCTGCCTCAAGATTTCTGACATCATCTAT
CTAAAAGCTGTGAACGTGCTGAACCTCACTCGACTGACATTTTTTTTCTTGATTCCTTTG
TTCATCATGATTGGGTGCTACTTGGTCATTATTCATAATCTCCTTCACGGCAGGACGTCT
AAGCTGAAACCCAAAGTCAAGGAGAAGTCCATAAGGATCATCATCACGCTGCTGGTGCAG
GTGCTCGTCTGCTTTATGCCCTTCCACATCTGTTTCGCTTTCCTGATGCTGGGAACGGGG
GAGAACAGTTACAATCCCTGGGGAGCCTTTACCACCTTCCTCATGAACCTCAGCACGTGT
CTGGATGTGATTCTCTACTACATCGTTTCAAAACAATTTCAGGCTCGAGTCATTAGTGTC
ATGCTATACCGTAATTACCTTCGAAGCATGCGCAGAAAAAGTTTCCGATCTGGTAGTCTA
CGGTCACTAAGCAATATAAACAGTGAAATGTTATGA
|
| Protein Properties |
|---|
| Number of Residues
| 331 |
| Molecular Weight
| 38133.3 |
| Theoretical pI
| 9.56 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
- ["27-47", "57-77", "96-116", "139-159", "192-212", "233-253", "269-289"]
|
| Protein Sequence
|
>N-arachidonyl glycine receptor
MITLNNQDQPVPFNSSHPDEYKIAALVFYSCIFIIGLFVNITALWVFSCTTKKRTTVTIY
MMNVALVDLIFIMTLPFRMFYYAKDEWPFGEYFCQILGALTVFYPSIALWLLAFISADRY
MAIVQPKYAKELKNTCKAVLACVGVWIMTLTTTTPLLLLYKDPDKDSTPATCLKISDIIY
LKAVNVLNLTRLTFFFLIPLFIMIGCYLVIIHNLLHGRTSKLKPKVKEKSIRIIITLLVQ
VLVCFMPFHICFAFLMLGTGENSYNPWGAFTTFLMNLSTCLDVILYYIVSKQFQARVISV
MLYRNYLRSMRRKSFRSGSLRSLSNINSEML
|
| External Links |
|---|
| GenBank ID Protein
| 148235349 |
| UniProtKB/Swiss-Prot ID
| Q14330 |
| UniProtKB/Swiss-Prot Entry Name
| GPR18_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_001098200.1 |
| GeneCard ID
| GPR18 |
| GenAtlas ID
| GPR18 |
| HGNC ID
| HGNC:4472 |
| References |
|---|
| General References
| Not Available |