Identification
HMDB Protein ID CDBP04746
Secondary Accession Numbers Not Available
Name Epididymal sperm-binding protein 1
Description Not Available
Synonyms
  1. Epididymal secretory protein 12
  2. hE12
Gene Name ELSPBP1
Protein Type Enzyme
Biological Properties
General Function Involved in single fertilization
Specific Function Binds to spermatozoa upon ejaculation and may play a role in sperm capacitation. Has phosphorylcholine-binding activity
GO Classification Not Available
Cellular Location
  1. Secreted
Pathways
Gene Properties
Chromosome Location Chromosome:1
Locus 19q13.33
SNPs ELSPBP1
Gene Sequence
>672 bp
ATGACCCGATGGTCCAGTTACCTGTTGGGATGGACAACCTTCCTTCTCTATTCCTATGAG
TCAAGTGGAGGGATGCATGAGGAATGTGTCTTTCCTTTCACCTACAAGGGATCTGTTTAC
TTCACTTGCACCCATATTCATAGCTTATCCCCTTGGTGTGCCACCAGAGCCGTGTACAAC
GGCCAGTGGAAGTACTGCCAGAGTGAAGATTACCCACGCTGTATCTTCCCTTTCATCTAT
CGAGGAAAGGCTTATAACAGCTGCATCTCCCAGGGCAGCTTCTTAGGCAGTCTGTGGTGC
TCAGTCACCTCTGTCTTCGATGAGAAACAGCAGTGGAAATTCTGTGAAACGAATGAGTAT
GGGGGAAATTCTCTCAGGAAGCCCTGCATCTTCCCCTCCATCTACAGAAATAATGTGGTC
TCTGATTGCATGGAGGATGAAAGCAACAAGCTCTGGTGCCCAACCACAGAGAACATGGAT
AAGGATGGAAAGTGGAGTTTCTGTGCCGACACCAGAATTTCCGCGTTGGTCCCTGGCTTT
CCTTGTCACTTTCCGTTCAACTATAAAAACAAGAATTATTTTAACTGCACTAACGAAGGA
TCAAAGGAGAACCTTGTGTGGTGTGCAACTTCTTACAACTACGACCAAGACCACACCTGG
GTGTATTGCTGA
Protein Properties
Number of Residues 223
Molecular Weight 26106.1
Theoretical pI 6.62
Pfam Domain Function
Signals
  • ["1-24"]
Transmembrane Regions
  • ["None"]
Protein Sequence
>Epididymal sperm-binding protein 1
MTRWSSYLLGWTTFLLYSYESSGGMHEECVFPFTYKGSVYFTCTHIHSLSPWCATRAVYN
GQWKYCQSEDYPRCIFPFIYRGKAYNSCISQGSFLGSLWCSVTSVFDEKQQWKFCETNEY
GGNSLRKPCIFPSIYRNNVVSDCMEDESNKLWCPTTENMDKDGKWSFCADTRISALVPGF
PCHFPFNYKNKNYFNCTNEGSKENLVWCATSYNYDQDHTWVYC
GenBank ID Protein 301601648
UniProtKB/Swiss-Prot ID Q96BH3
UniProtKB/Swiss-Prot Entry Name ESPB1_HUMAN
PDB IDs Not Available
GenBank Gene ID NM_022142.4
GeneCard ID ELSPBP1
GenAtlas ID ELSPBP1
HGNC ID HGNC:14417
References
General References Not Available