Identification |
HMDB Protein ID
| CDBP04744 |
Secondary Accession Numbers
| Not Available |
Name
| Fibroblast growth factor 8 |
Description
| Not Available |
Synonyms
|
- AIGF
- Androgen-induced growth factor
- FGF-8
- HBGF-8
- Heparin-binding growth factor 8
|
Gene Name
| FGF8 |
Protein Type
| Receptor |
Biological Properties |
General Function
| Involved in growth factor activity |
Specific Function
| Stimulates growth of the cells in an autocrine manner. Mediates hormonal action on the growth of cancer cells |
GO Classification
|
Function |
binding |
protein binding |
receptor binding |
growth factor activity |
|
Cellular Location
|
- Secreted
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Chromosome:1 |
Locus
| 10q24 |
SNPs
| FGF8 |
Gene Sequence
|
>702 bp
ATGGGCAGCCCCCGCTCCGCGCTGAGCTGCCTGCTGTTGCACTTGCTGGTCCTCTGCCTC
CAAGCCCAGGAAGGCCCGGGCAGGGGCCCTGCGCTGGGCAGGGAGCTCGCTTCCCTGTTC
CGGGCTGGCCGGGAGCCCCAGGGTGTCTCCCAACAGCATGTGAGGGAGCAGAGCCTGGTG
ACGGATCAGCTCAGCCGCCGCCTCATCCGGACCTACCAACTCTACAGCCGCACCAGCGGG
AAGCACGTGCAGGTCCTGGCCAACAAGCGCATCAACGCCATGGCAGAGGACGGCGACCCC
TTCGCAAAGCTCATCGTGGAGACGGACACCTTTGGAAGCAGAGTTCGAGTCCGAGGAGCC
GAGACGGGCCTCTACATCTGCATGAACAAGAAGGGGAAGCTGATCGCCAAGAGCAACGGC
AAAGGCAAGGACTGCGTCTTCACGGAGATTGTGCTGGAGAACAACTACACAGCGCTGCAG
AATGCCAAGTACGAGGGCTGGTACATGGCCTTCACCCGCAAGGGCCGGCCCCGCAAGGGC
TCCAAGACGCGGCAGCACCAGCGTGAGGTCCACTTCATGAAGCGGCTGCCCCGGGGCCAC
CACACCACCGAGCAGAGCCTGCGCTTCGAGTTCCTCAACTACCCGCCCTTCACGCGCAGC
CTGCGCGGCAGCCAGAGGACTTGGGCCCCCGAGCCCCGATAG
|
Protein Properties |
Number of Residues
| 233 |
Molecular Weight
| 26525.3 |
Theoretical pI
| 11.04 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
|
Protein Sequence
|
>Fibroblast growth factor 8
MGSPRSALSCLLLHLLVLCLQAQEGPGRGPALGRELASLFRAGREPQGVSQQHVREQSLV
TDQLSRRLIRTYQLYSRTSGKHVQVLANKRINAMAEDGDPFAKLIVETDTFGSRVRVRGA
ETGLYICMNKKGKLIAKSNGKGKDCVFTEIVLENNYTALQNAKYEGWYMAFTRKGRPRKG
SKTRQHQREVHFMKRLPRGHHTTEQSLRFEFLNYPPFTRSLRGSQRTWAPEPR
|
External Links |
GenBank ID Protein
| 15147348 |
UniProtKB/Swiss-Prot ID
| P55075 |
UniProtKB/Swiss-Prot Entry Name
| FGF8_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| NM_033164.3 |
GeneCard ID
| FGF8 |
GenAtlas ID
| FGF8 |
HGNC ID
| HGNC:3686 |
References |
General References
| Not Available |