Identification
HMDB Protein ID CDBP04744
Secondary Accession Numbers Not Available
Name Fibroblast growth factor 8
Description Not Available
Synonyms
  1. AIGF
  2. Androgen-induced growth factor
  3. FGF-8
  4. HBGF-8
  5. Heparin-binding growth factor 8
Gene Name FGF8
Protein Type Receptor
Biological Properties
General Function Involved in growth factor activity
Specific Function Stimulates growth of the cells in an autocrine manner. Mediates hormonal action on the growth of cancer cells
GO Classification
Function
binding
protein binding
receptor binding
growth factor activity
Cellular Location
  1. Secreted
Pathways
Gene Properties
Chromosome Location Chromosome:1
Locus 10q24
SNPs FGF8
Gene Sequence
>702 bp
ATGGGCAGCCCCCGCTCCGCGCTGAGCTGCCTGCTGTTGCACTTGCTGGTCCTCTGCCTC
CAAGCCCAGGAAGGCCCGGGCAGGGGCCCTGCGCTGGGCAGGGAGCTCGCTTCCCTGTTC
CGGGCTGGCCGGGAGCCCCAGGGTGTCTCCCAACAGCATGTGAGGGAGCAGAGCCTGGTG
ACGGATCAGCTCAGCCGCCGCCTCATCCGGACCTACCAACTCTACAGCCGCACCAGCGGG
AAGCACGTGCAGGTCCTGGCCAACAAGCGCATCAACGCCATGGCAGAGGACGGCGACCCC
TTCGCAAAGCTCATCGTGGAGACGGACACCTTTGGAAGCAGAGTTCGAGTCCGAGGAGCC
GAGACGGGCCTCTACATCTGCATGAACAAGAAGGGGAAGCTGATCGCCAAGAGCAACGGC
AAAGGCAAGGACTGCGTCTTCACGGAGATTGTGCTGGAGAACAACTACACAGCGCTGCAG
AATGCCAAGTACGAGGGCTGGTACATGGCCTTCACCCGCAAGGGCCGGCCCCGCAAGGGC
TCCAAGACGCGGCAGCACCAGCGTGAGGTCCACTTCATGAAGCGGCTGCCCCGGGGCCAC
CACACCACCGAGCAGAGCCTGCGCTTCGAGTTCCTCAACTACCCGCCCTTCACGCGCAGC
CTGCGCGGCAGCCAGAGGACTTGGGCCCCCGAGCCCCGATAG
Protein Properties
Number of Residues 233
Molecular Weight 26525.3
Theoretical pI 11.04
Pfam Domain Function
Signals
  • ["1-22"]
Transmembrane Regions
  • ["None"]
Protein Sequence
>Fibroblast growth factor 8
MGSPRSALSCLLLHLLVLCLQAQEGPGRGPALGRELASLFRAGREPQGVSQQHVREQSLV
TDQLSRRLIRTYQLYSRTSGKHVQVLANKRINAMAEDGDPFAKLIVETDTFGSRVRVRGA
ETGLYICMNKKGKLIAKSNGKGKDCVFTEIVLENNYTALQNAKYEGWYMAFTRKGRPRKG
SKTRQHQREVHFMKRLPRGHHTTEQSLRFEFLNYPPFTRSLRGSQRTWAPEPR
GenBank ID Protein 15147348
UniProtKB/Swiss-Prot ID P55075
UniProtKB/Swiss-Prot Entry Name FGF8_HUMAN
PDB IDs Not Available
GenBank Gene ID NM_033164.3
GeneCard ID FGF8
GenAtlas ID FGF8
HGNC ID HGNC:3686
References
General References Not Available